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The robustness of large language models (LLMs) becomes increasingly important as their use rapidly grows in a wide range of domains. Retrieval-Augmented Generation (RAG) is considered as a means to improve the trustworthiness of text…

Computation and Language · Computer Science 2025-05-22 Zhibo Hu , Chen Wang , Yanfeng Shu , Helen , Paik , Liming Zhu

In the age of mobile internet, user data, often referred to as memories, is continuously generated on personal devices. Effectively managing and utilizing this data to deliver services to users is a compelling research topic. In this paper,…

Computation and Language · Computer Science 2024-10-01 Zheng Wang , Zhongyang Li , Zeren Jiang , Dandan Tu , Wei Shi

Retrieval-Augmented Generation (RAG), which integrates external knowledge into Large Language Models (LLMs), has proven effective in enabling LLMs to produce more accurate and reliable responses. However, it remains a significant challenge…

Computation and Language · Computer Science 2025-02-11 Yan Weng , Fengbin Zhu , Tong Ye , Haoyan Liu , Fuli Feng , Tat-Seng Chua

Multimodal Retrieval-Augmented Generation (MRAG) enhances large language models (LLMs) by integrating multimodal data (text, images, videos) into retrieval and generation processes, overcoming the limitations of text-only…

Information Retrieval · Computer Science 2025-04-15 Lang Mei , Siyu Mo , Zhihan Yang , Chong Chen

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

The Machine Assisted Generation, Comparison, and Calibration (MAGCC) framework provides machine assistance and automation of recurrent crucial steps and processes in the development, implementation, testing, and use of scientific simulation…

Artificial Intelligence · Computer Science 2022-04-25 Chase Cockrell , Scott Christley , Gary An

Retrieving molecular structures from tandem mass spectra is a crucial step in rapid compound identification. Existing retrieval methods, such as traditional mass spectral library matching, suffer from limited spectral library coverage,…

Machine Learning · Computer Science 2025-11-11 Yiwen Zhang , Keyan Ding , Yihang Wu , Xiang Zhuang , Yi Yang , Qiang Zhang , Huajun Chen

The current technology landscape lacks a foundational AI model for solving process engineering calculations. In this work, we introduce a novel autonomous agent framework leveraging Retrieval-Augmented Instruction-Tuning (RAIT) to enhance…

Software Engineering · Computer Science 2024-08-29 Sagar Srinivas Sakhinana , Geethan Sannidhi , Venkataramana Runkana

Magnetic Resonance Fingerprinting (MRF) is an emerging technology with the potential to revolutionize radiology and medical diagnostics. In comparison to traditional magnetic resonance imaging (MRI), MRF enables the rapid, simultaneous,…

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

RNA function is tied to secondary structure, operating through dynamic and heterogeneous structural ensembles. While current analysis tools typically output single static structures or averaged contact maps, chemical probing methods like…

Biomolecules · Quantitative Biology 2026-05-20 Giuseppe Sacco , Jianhui Li , Redmond P. Smyth , Guido Sanguinetti , Giovanni Bussi

Retrieval-augmented large language models (LLMs) have been remarkably competent in various NLP tasks. However, it was observed by previous works that retrieval is not always helpful, especially when the LLM is already knowledgeable on the…

Computation and Language · Computer Science 2024-12-16 Chengkai Huang , Yu Xia , Rui Wang , Kaige Xie , Tong Yu , Julian McAuley , Lina Yao

Retrieval-Augmented Generation (RAG) is increasingly employed in generative AI-driven scientific workflows to integrate rapidly evolving scientific knowledge bases, yet its reliability is frequently compromised by non-determinism in their…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-24 Baiqiang Wang , Dongfang Zhao , Nathan R Tallent , Luanzheng Guo

Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Song , William Han , Tony Chen , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Retrieval Augmented Generation (RAG) systems often struggle with domain-specific knowledge due to performance deterioration of pre-trained embeddings and prohibitive computational costs of large language model (LLM)-based retrievers. While…

Information Retrieval · Computer Science 2025-09-15 Yao Zhao , Yantian Ding , Zhiyue Zhang , Dapeng Yao , Yanxun Xu

Large Language Models (LLMs) are becoming essential tools for various natural language processing tasks but often suffer from generating outdated or incorrect information. Retrieval-Augmented Generation (RAG) addresses this issue by…

Recently, Graph Transformer (GT) models have been widely used in the task of Molecular Property Prediction (MPP) due to their high reliability in characterizing the latent relationship among graph nodes (i.e., the atoms in a molecule).…

Machine Learning · Computer Science 2023-10-12 Wentao Yu , Shuo Chen , Chen Gong , Gang Niu , Masashi Sugiyama

Advanced Multimodal Large Language Models (MLLMs) struggle with recent Knowledge-based VQA tasks, such as INFOSEEK and Encyclopedic-VQA, due to their limited and frozen knowledge scope, often leading to ambiguous and inaccurate responses.…

Artificial Intelligence · Computer Science 2024-11-25 Tao Zhang , Ziqi Zhang , Zongyang Ma , Yuxin Chen , Zhongang Qi , Chunfeng Yuan , Bing Li , Junfu Pu , Yuxuan Zhao , Zehua Xie , Jin Ma , Ying Shan , Weiming Hu

Retrieval-augmented generation (RAG) has emerged as a pivotal method for expanding the knowledge of large language models. To handle complex queries more effectively, researchers developed Adaptive-RAG (A-RAG) to enhance the generated…

Artificial Intelligence · Computer Science 2025-05-27 Jie Ou , Jinyu Guo , Shuaihong Jiang , Zhaokun Wang , Libo Qin , Shunyu Yao , Wenhong Tian

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu
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