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Visual Question Answering systems face reliability issues due to hallucinations, where models generate answers misaligned with visual input or factual knowledge. While Retrieval Augmented Generation frameworks mitigate this issue by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ruoshuang Du , Xin Sun , Qiang Liu , Bowen Song , Zhongqi Chen , Weiqiang Wang , Liang Wang

In this study, we explore the fine-tuning of Large Language Models (LLMs) to better support policymakers in their crucial work of understanding, analyzing, and crafting legal regulations. To equip the model with a deep understanding of…

Computation and Language · Computer Science 2025-11-06 One Octadion , Bondan Sapta Prakoso , Nanang Yudi Setiawan , Novanto Yudistira

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its…

Automated radiology report generation has gained increasing attention with the rise of deep learning and large language models. However, fully generative approaches often suffer from hallucinations and lack clinical grounding, limiting…

Quantitative Methods · Quantitative Biology 2026-05-01 Himadri S Samanta

Large Language Models (LLMs) have shown remarkable capabilities across diverse tasks, yet they face inherent limitations such as constrained parametric knowledge and high retraining costs. Retrieval-Augmented Generation (RAG) augments the…

Information Retrieval · Computer Science 2025-08-26 Leqian Li , Dianxi Shi , Jialu Zhou , Xinyu Wei , Mingyue Yang , Songchang Jin , Shaowu Yang

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Generating new molecules with specified chemical and biological properties via generative models has emerged as a promising direction for drug discovery. However, existing methods require extensive training/fine-tuning with a large dataset,…

Quantitative Methods · Quantitative Biology 2023-04-25 Zichao Wang , Weili Nie , Zhuoran Qiao , Chaowei Xiao , Richard Baraniuk , Anima Anandkumar

Large language models (LLMs) have achieved strong empirical performance in various fields, benefiting from their huge amount of parameters that store knowledge. However, LLMs still suffer from several key issues, such as hallucination…

Computation and Language · Computer Science 2026-05-20 Shangyu Wu , Ying Xiong , Yufei Cui , Haolun Wu , Can Chen , Ye Yuan , Lianming Huang , Xue Liu , Tei-Wei Kuo , Nan Guan , Chun Jason Xue

Molecular property prediction and generative design via deep learning models has been the subject of intense research given its potential to accelerate development of new, high-performance materials. More recently, these workflows have been…

Artificial Intelligence · Computer Science 2024-12-16 Nathaniel H. Park , Tiffany J. Callahan , James L. Hedrick , Tim Erdmann , Sara Capponi

Fragment-Based Drug Discovery (FBDD) is a popular approach in early drug development, but designing effective linkers to combine disconnected molecular fragments into chemically and pharmacologically viable candidates remains challenging.…

Machine Learning · Computer Science 2025-09-24 Xuefeng Liu , Songhao Jiang , Qinan Huang , Tinson Xu , Ian Foster , Mengdi Wang , Hening Lin , Rick Stevens

The evolution of digital manufacturing requires intelligent Question Answering (QA) systems that can seamlessly integrate and analyze complex multi-modal data, such as text, images, formulas, and tables. Conventional Retrieval Augmented…

Computational Engineering, Finance, and Science · Computer Science 2026-01-27 Yunqing Li , Zihan Dong , Farhad Ameri , Jianbang Zhang

Accurate multi-modal document retrieval is crucial for Retrieval-Augmented Generation (RAG), yet existing benchmarks do not fully capture real-world challenges with their current design. We introduce REAL-MM-RAG, an automatically generated…

Information Retrieval · Computer Science 2025-02-19 Navve Wasserman , Roi Pony , Oshri Naparstek , Adi Raz Goldfarb , Eli Schwartz , Udi Barzelay , Leonid Karlinsky

We study question answering in the domain of radio regulations, a legally sensitive and high-stakes area. We propose a telecom-specific Retrieval-Augmented Generation (RAG) pipeline and introduce, to our knowledge, the first multiple-choice…

Information Retrieval · Computer Science 2025-11-14 Zakaria El Kassimi , Fares Fourati , Mohamed-Slim Alouini

We present a systematic investigation of Multi-modal Retrieval Augmented Multi-modal Generation (M$^2$RAG), a novel task that enables foundation models to process multi-modal web content and generate multi-modal responses, which exhibits…

Computation and Language · Computer Science 2025-05-26 Zi-Ao Ma , Tian Lan , Rong-Cheng Tu , Yong Hu , Yu-Shi Zhu , Tong Zhang , Heyan Huang , Zhijing Wu , Xian-Ling Mao

Large language models (LLMs) struggle to effectively utilize a growing number of external tools, such as those defined by the Model Context Protocol (MCP)\cite{IntroducingMCP}, due to prompt bloat and selection complexity. We introduce…

Artificial Intelligence · Computer Science 2025-05-07 Tiantian Gan , Qiyao Sun

Fragment-based drug discovery, in which molecular fragments are assembled into new molecules with desirable biochemical properties, has achieved great success. However, many fragment-based molecule generation methods show limited…

Machine Learning · Computer Science 2024-11-20 Seul Lee , Karsten Kreis , Srimukh Prasad Veccham , Meng Liu , Danny Reidenbach , Saee Paliwal , Arash Vahdat , Weili Nie

The versatility of large language models (LLMs) has been explored across various sectors, but their application in healthcare poses challenges, particularly in the domain of pharmaceutical contraindications where accurate and reliable…

Artificial Intelligence · Computer Science 2025-08-11 Byeonghun Bang , Jongsuk Yoon , Dong-Jin Chang , Seho Park , Yong Oh Lee