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Local quantum annealing (LQA), an iterative algorithm, is designed to solve combinatorial optimization problems. It draws inspiration from QA, which utilizes adiabatic time evolution to determine the global minimum of a given objective…

Quantum Physics · Physics 2025-01-07 Shunta Arai , Satoshi Takabe

Quantum annealing is a heuristic algorithm for searching the ground state of an Ising model. Heuristic algorithms aim to obtain near-optimal solutions with a reasonable computation time. Accordingly, many algorithms have so far been…

Quantum Physics · Physics 2022-11-09 Shuntaro Okada , Masayuki Ohzeki

Hybrid classical quantum learning is often bottlenecked by communication overhead and approximation error from generic variational ansatzes. In this study, we introduce Neural Native Quantum Arithmetic (NNQA), which compiles classically…

Quantum Physics · Physics 2026-03-31 Ziqing Guo , Jie Li , Yong Chen , Ziwen Pan

Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

The development of novel transparent conducting materials (TCMs) is essential for enhancing the performance and reducing the cost of next-generation devices such as solar cells and displays. In this research, we focus on the…

Materials Science · Physics 2025-08-01 Daisuke Makino , Tatsuya Goto , Yoshinori Suga

Quantum algorithms are emerging tools in the design of functional materials due to their powerful solution space search capability. How to balance the high price of quantum computing resources and the growing computing needs has become an…

Quantum Physics · Physics 2024-05-13 Zhihao Xu , Wenjie Shang , Seongmin Kim , Alexandria Bobbitt , Eungkyu Lee , Tengfei Luo

Building on previous research on frequency allocation optimization for superconducting circuit quantum processors, this work incorporates several new techniques to improve overall solution quality. New features include tightening…

Quantum Physics · Physics 2025-01-27 Zewen Zhang , Pranav Gokhale , Jeffrey M. Larson

Retrieval-Augmented Generation enhances language models by retrieving relevant information from external knowledge bases, relying on high-dimensional vector embeddings typically stored in float32 precision. However, storing these embeddings…

The steady progress of quantum hardware is motivating the search for novel quantum algorithm optimization strategies for near-term, real-world applications. In this study, we propose a novel feature map optimization strategy for Quantum…

Quantum Physics · Physics 2025-03-31 Roberto Moretti , Andrea Giachero , Voica Radescu , Michele Grossi

Variational quantum algorithms (VQAs) for combinatorial optimization routinely employ entangling gates as a default design choice, yet the role of entanglement, in its amount and structure, remains poorly understood. This gap is…

Hydrogen integration into microgrids facilitates the absorption of intermittencies from renewable energy resources. However, significant challenges remain due to complex optimization problems, particularly in large-scale applications…

Systems and Control · Electrical Eng. & Systems 2026-03-10 Arash Khalatbarisoltani , Amin Mahmoudi , Jie Han , Muhammad Saeed , Wenxue Liu , Jinwen Li , Solmaz Kahourzade , Amirmehdi Yazdani , Xiaosong Hu

Quantum computing has gained a lot of attention recently, and scientists have seen potential applications in this field using quantum computing for Cryptography and Communication to Machine Learning and Healthcare. Protein folding has been…

Quantum Physics · Physics 2022-11-16 Hasan Mustafa , Sai Nandan Morapakula , Prateek Jain , Srinjoy Ganguly

In variational quantum algorithms, parameterization is typically applied to single-qubit gates.In this study, we instead parameterize a generalized controlled gate and propose an algorithm to locally minimize the cost function by maximally…

Quantum annealing (QA) provides us with a way to solve combinatorial optimization problems. In the previous demonstration of the QA, a superconducting flux qubit (FQ) was used. However, the flux qubits in these demonstrations have a short…

Quantum Physics · Physics 2020-02-19 Yuichiro Matsuzaki , Hideaki Hakoshima , Yuya Seki , Shiro Kawabata

Motivation: RNA design aims to find RNA sequences that fold into a given target secondary structure, a problem also known as RNA inverse folding. However, not all target structures are designable. Recent advances in RNA designability have…

Data Structures and Algorithms · Computer Science 2026-04-28 Tianshuo Zhou , David H. Mathews , Liang Huang

The RNA Inverse Folding problem comes from computational biology. The goal is to find a molecule that has a given folding. It is important for scientific fields such as bioengineering, pharmaceutical research, biochemistry, synthetic…

Artificial Intelligence · Computer Science 2020-05-21 Tristan Cazenave , Thomas Fournier

We propose a hybrid classical-quantum digitized-counterdiabatic algorithm to tackle the protein folding problem on a tetrahedral lattice. Digitized-counterdiabatic quantum computing is a paradigm developed to compress quantum algorithms via…

Quantum Physics · Physics 2023-07-13 Pranav Chandarana , Narendra N. Hegade , Iraitz Montalban , Enrique Solano , Xi Chen

The RNA inverse folding problem, a key challenge in RNA design, involves identifying nucleotide sequences that can fold into desired secondary structures, which are critical for ensuring molecular stability and function. The inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Guang Yang , Lei Fan

To increase efficiency in automotive manufacturing, newly produced vehicles can move autonomously from the production line to the distribution area. This requires an optimal placement of sensors to ensure full coverage while minimizing the…

Emerging Technologies · Computer Science 2025-07-23 Nico Kraus , Marvin Erdmann , Alexander Kuzmany , Daniel Porawski , Jonas Stein

It is NP-complete to find non-negative factors $W$ and $H$ with fixed rank $r$ from a non-negative matrix $X$ by minimizing $\|X-WH^\top\|_F^2$. Although the separability assumption (all data points are in the conical hull of the extreme…

Quantum Physics · Physics 2018-02-23 Yuxuan Du , Tongliang Liu , Yinan Li , Runyao Duan , Dacheng Tao