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Knowledge Graph-based Question Answering (KGQA) plays a pivotal role in complex reasoning tasks but remains constrained by two persistent challenges: the structural heterogeneity of Knowledge Graphs(KGs) often leads to semantic mismatch…

Computation and Language · Computer Science 2026-05-19 Peng Yu , En Xu , Bin Chen , Haibiao Chen , Yinfei Xu

Attributed Graph Clustering (AGC) is a fundamental unsupervised task that partitions nodes into cohesive groups by jointly modeling structural topology and node attributes. While the advent of graph neural networks and self-supervised…

Machine Learning · Computer Science 2026-03-24 Yunhui Liu , Yue Liu , Yongchao Liu , Tao Zheng , Stan Z. Li , Xinwang Liu , Tieke He

We propose SLIM (Stochastic Learning and Inference in overidentified Models), a scalable stochastic approximation framework for nonlinear GMM. SLIM forms iterative updates from independent mini-batches of moments and their derivatives,…

Econometrics · Economics 2025-11-03 Xiaohong Chen , Min Seong Kim , Sokbae Lee , Myung Hwan Seo , Myunghyun Song

Searching for similar genomic sequences is an essential and fundamental step in biomedical research and an overwhelming majority of genomic analyses. State-of-the-art computational methods performing such comparisons fail to cope with the…

Data Structures and Algorithms · Computer Science 2024-07-11 Mohammed Alser , Julien Eudine , Onur Mutlu

When studying the association between treatment and a clinical outcome, a parametric multivariable model of the conditional outcome expectation is often used to adjust for covariates. The treatment coefficient of the outcome model targets a…

Methodology · Statistics 2026-05-07 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

Image matching is a fundamental computer vision problem. While learning-based methods achieve state-of-the-art performance on existing benchmarks, they generalize poorly to in-the-wild images. Such methods typically need to train separate…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Xuelun Shen , Zhipeng Cai , Wei Yin , Matthias Müller , Zijun Li , Kaixuan Wang , Xiaozhi Chen , Cheng Wang

Item indexing, which maps a large corpus of items into compact discrete representations, is critical for both discriminative and generative recommender systems, yet existing Vector Quantization (VQ)-based approaches struggle with the highly…

Information Retrieval · Computer Science 2026-01-29 Jing Yan , Yimeng Bai , Zongyu Liu , Yahui Liu , Junwei Wang , Jingze Huang , Haoda Li , Sihao Ding , Shaohui Ruan , Yang Zhang

High-throughput pheno-, geno-, and envirotyping allows characterization of plant genotypes and the trials they are evaluated in, producing different types of data. These different data modalities can be integrated into statistical or…

Grokking occurs when a model achieves high training accuracy but generalization to unseen test points happens long after that. This phenomenon was initially observed on a class of algebraic problems, such as learning modular arithmetic…

Machine Learning · Statistics 2026-04-02 Marcel Tomàs Bernal , Neil Rohit Mallinar , Mikhail Belkin

The Generalized Additive Model (GAM) is a powerful tool and has been well studied. This model class helps to identify additive regression structure. Via available test procedures one may identify the regression structure even sharper if…

Methodology · Statistics 2020-09-11 Rong Liu , Wolfgang Karl Härdle

Single-Cell RNA sequencing (scRNA-seq) measurements have facilitated genome-scale transcriptomic profiling of individual cells, with the hope of deconvolving cellular dynamic changes in corresponding cell sub-populations to better…

Genomics · Quantitative Biology 2021-04-06 Seyednami Niyakan , Ehsan Hajiramezanali , Shahin Boluki , Siamak Zamani Dadaneh , Xiaoning Qian

Structural assessment of biomolecular complexes is vital for translating molecular models into functional insights, shaping our understanding of biology and aiding drug discovery. However, current structure-based scoring functions often…

Attribute-missing graph clustering has emerged as a significant unsupervised task, where only attribute vectors of partial nodes are available and the graph structure is intact. The related models generally follow the two-step paradigm of…

Machine Learning · Computer Science 2025-10-30 Mulin Chen , Bocheng Wang , Jiaxin Zhong , Zongcheng Miao , Xuelong Li

It is appealing but challenging to achieve real-time deep neural network (DNN) inference on mobile devices because even the powerful modern mobile devices are considered as ``resource-constrained'' when executing large-scale DNNs. It…

Machine Learning · Computer Science 2021-08-26 Wei Niu , Zhengang Li , Xiaolong Ma , Peiyan Dong , Gang Zhou , Xuehai Qian , Xue Lin , Yanzhi Wang , Bin Ren

In multi-vector retrieval, both queries and data are represented as sets of high-dimensional vectors, enabling finer-grained semantic matching and improving retrieval quality over single-vector approaches. However, its practical adoption is…

Information Retrieval · Computer Science 2026-03-24 Yao Tian , Zhoujin Tian , Xi Zhao , Ruiyuan Zhang , Xiaofang Zhou

An open question in deep clustering is how to understand what in the image is creating the cluster assignments. This visual understanding is essential to be able to trust the results of an inherently complex algorithm like deep learning,…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Sarah Ryan , Nichole Carlson , Harris Butler , Tasha Fingerlin , Lisa Maier , Fuyong Xing

Structural biology relies on accurate three-dimensional biomolecular structures to advance our understanding of biological functions, disease mechanisms, and therapeutics. While recent advances in deep learning have enabled the development…

Biomolecules · Quantitative Biology 2025-04-02 Yizhen Luo , Jiashuo Wang , Siqi Fan , Zaiqing Nie

Predicting transcriptional responses to genetic perturbations is a central problem in functional genomics. In practice, perturbation responses are rarely gene-independent but instead manifest as coordinated, program-level transcriptional…

Genomics · Quantitative Biology 2026-02-06 Jiafa Ruan , Ruijie Quan , Zongxin Yang , Liyang Xu , Yi Yang

Current genomic foundation models (GFMs) rely on extensive neural computation to implicitly approximate conserved biological motifs from single-nucleotide inputs. We propose Gengram, a conditional memory module that introduces an explicit…

Inference from tabular data, collections of continuous and categorical variables organized into matrices, is a foundation for modern technology and science. Yet, in contrast to the explosive changes in the rest of AI, the best practice for…

Machine Learning · Computer Science 2026-04-07 Daniel Beaglehole , David Holzmüller , Adityanarayanan Radhakrishnan , Mikhail Belkin