Related papers: Evolutionary Advantage of Diversity-Generating Ret…
Deep generative models (DGMs) are data-eager because learning a complex model on limited data suffers from a large variance and easily overfits. Inspired by the classical perspective of the bias-variance tradeoff, we propose regularized…
Evolving systems, be it an antibody repertoire in the face of mutating pathogens or a microbial population exposed to varied antibiotics, constantly search for adaptive solutions in time-varying fitness landscapes. Generalists correspond to…
Over the past twenty years, artificial Gene Regulatory Networks (GRNs) have shown their capacity to solve real-world problems in various domains such as agent control, signal processing and artificial life experiments. They have also…
Radiology Report Generation (RRG) automates the creation of radiology reports from medical imaging, enhancing the efficiency of the reporting process. Longitudinal Radiology Report Generation (LRRG) extends RRG by incorporating the ability…
Neural architectures inspired by our own human cognitive system, such as the recently introduced world models, have been shown to outperform traditional deep reinforcement learning (RL) methods in a variety of different domains. Instead of…
The evolutionary fitness landscape of biological molecules is extremely sparse and heterogeneous, with functional sequences forming isolated dense ``islands'' within a vast combinatorial space of largely non-functional variants. Protein…
Renewable energy resources (RERs) have been increasingly integrated into distribution networks (DNs) for decarbonization. However, the variable nature of RERs introduces uncertainties to DNs, frequently resulting in voltage fluctuations…
Retrieval-augmented generation (RAG) enhances large language models (LLMs) by incorporating external knowledge, but existing approaches indiscriminately trigger retrieval and rely on single-path evidence construction, often introducing…
Heterogeneous Face Recognition (HFR) is a challenging issue because of the large domain discrepancy and a lack of heterogeneous data. This paper considers HFR as a dual generation problem, and proposes a novel Dual Variational Generation…
Electron ptychography enables dose-efficient atomic-resolution imaging, but conventional reconstruction algorithms suffer from noise sensitivity, slow convergence, and extensive manual hyperparameter tuning for regularization, especially in…
When solving inverse problems in geophysical imaging, deep generative models (DGMs) may be used to enforce the solution to display highly structured spatial patterns which are supported by independent information (e.g. the geological…
Reinforcement Learning (RL) has achieved impressive performance in many complex environments due to the integration with Deep Neural Networks (DNNs). At the same time, Genetic Algorithms (GAs), often seen as a competing approach to RL, had…
Received waveforms contain rich information for both range information and environment semantics. However, its full potential is hard to exploit under multipath and non-line-of-sight conditions. This paper proposes a deep generative model…
We present Brownian dynamics simulations of the facilitated diffusion of a protein, modelled as a sphere with a binding site on its surface, along DNA, modelled as a semi-flexible polymer. We consider both the effect of DNA organisation in…
Efficient low-variance gradient estimation enabled by the reparameterization trick (RT) has been essential to the success of variational autoencoders. Doubly-reparameterized gradients (DReGs) improve on the RT for multi-sample variational…
Horizontal gene transfer is an important factor in bacterial evolution that can act across species boundaries. Yet, we know little about rate and genomic targets of cross-lineage gene transfer, and about its effects on the recipient…
Predicting how cells respond to genetic perturbations is fundamental to understanding gene function, disease mechanisms, and therapeutic development. While recent deep learning approaches have shown promise in modeling single-cell…
Viruses can amplify their genomes following different replication modes (RMs) ranging from the stamping machine replication (SMR) model to the geometric replication (GR) model. Different RMs are expected to produce different evolutionary…
Sex chromosomes have evolved repeatedly across the Tree of Life, yet their evolutionary fates differ strikingly. In sharp contrast to mammals and birds with degenerated, stable Y/W chromosomes, in most amphibians, teleosts, non avian…
Deep learning-based physical-layer secret key generation (PKG) has been used to overcome the imperfect uplink/downlink channel reciprocity in frequency division duplexing (FDD) orthogonal frequency division multiplexing (OFDM) systems.…