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In cryo-electron microscopy (EM), molecular structures are determined from large numbers of projection images of individual particles. To harness the full power of this single-molecule information, we use the Bayesian inference of EM…

Biomolecules · Quantitative Biology 2018-01-17 Pilar Cossio , David Rohr , Fabio Baruffa , Markus Rampp , Volker Lindenstruth , Gerhard Hummer

Model merging aims to combine multiple task-specific expert models into a single model while preserving generalization across diverse tasks. However, interference among experts, especially when they are trained on different objectives,…

Computation and Language · Computer Science 2026-04-09 Bo Xu , Haotian Wu , Hehai Lin , Weiquan Huang , Beier Zhu , Yao Shu , Chengwei Qin

General Matrix Multiplication (GEMM) is a critical operation underpinning a wide range of applications in high-performance computing (HPC) and artificial intelligence (AI). The emergence of hardware optimized for low-precision arithmetic…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-21 Qiao Zhang , Rabab Alomairy , Dali Wang , Zhuowei Gu , Qinglei Cao

This paper proposes a multi-step probabilistic forecasting framework using a single neural-network based model to generate simultaneous point and interval forecasts. Our approach ensures non-crossing prediction intervals (PIs) through a…

Machine Learning · Computer Science 2026-04-21 Worachit Amnuaypongsa , Yotsapat Suparanonrat , Pana Wanitchollakit , Jitkomut Songsiri

Machine learning interatomic potentials have revolutionized complex materials design by enabling rapid exploration of material configurational spaces via crystal structure prediction with ab initio accuracy. However, critical challenges…

Autonomous Experimentation Platforms (AEPs) are advanced manufacturing platforms that, under intelligent control, can sequentially search the material design space (MDS) and identify parameters with the desired properties. At the heart of…

Machine Learning · Computer Science 2023-02-28 Ahmed Shoyeb Raihan , Imtiaz Ahmed

By locally encoding raw data into intermediate features, collaborative inference enables end users to leverage powerful deep learning models without exposure of sensitive raw data to cloud servers. However, recent studies have revealed that…

Machine Learning · Computer Science 2025-04-04 Song Xia , Yi Yu , Wenhan Yang , Meiwen Ding , Zhuo Chen , Ling-Yu Duan , Alex C. Kot , Xudong Jiang

Physics-informed neural networks (PINNs), owing to their mesh-free nature, offer a powerful approach for solving high-dimensional partial differential equations (PDEs) in complex geometries, including irregular domains. This capability…

Numerical Analysis · Mathematics 2025-06-06 Hanfei Zhou , Lei Shi

Denoising Diffusion Probabilistic Models (DDPMs) have significantly advanced generative AI, achieving impressive results in high-quality image and data generation. However, enhancing fidelity without compromising semantic content remains a…

The so-called matrix-element method (MEM) has long been used successfully as a classification tool in particle physics searches. In the presence of invisible final state particles, the traditional MEM typically assigns probabilities to an…

High Energy Physics - Phenomenology · Physics 2019-08-26 Stefan von Buddenbrock , Olivier Mattelaer , Michael Spannowsky

The phenomena of Spectral Bias, where the higher frequency components of a function being learnt in a feedforward Artificial Neural Network (ANN) are seen to converge more slowly than the lower frequencies, is observed ubiquitously across…

Machine Learning · Computer Science 2023-07-20 Kaumudi Joshi , Vukka Snigdha , Arya Kumar Bhattacharya

Neutron and X-ray reflectometry are powerful techniques facilitating the study of the structure of interfacial materials. The analysis of these techniques is ill-posed in nature requiring the application of a model-dependent methods. This…

Soft Condensed Matter · Physics 2022-07-22 Andrew R. McCluskey , Thomas Arnold , Joshaniel F. K. Cooper , Tim Snow

The ability to image materials at the microscale from long-wavelength wave data is a major challenge to the geophysical, engineering and medical fields. Here, we present a framework to constrain microstructure geometry and properties from…

Geophysics · Physics 2021-04-19 Wouter Klessens , Ivan Vasconcelos , Yang Jiao

We present a methodology for designing metagratings for perfect anomalous refraction, based on multilayered loaded wire arrays. In recent work, it has been shown that such structures can implement perfect anomalous deflection and beam…

Applied Physics · Physics 2018-04-09 Ariel Epstein , Oshri Rabinovich

The expectation-maximization (EM) algorithm is a well-known iterative method for computing maximum likelihood estimates from incomplete data. Despite its numerous advantages, a main drawback of the EM algorithm is its frequently observed…

Computation · Statistics 2018-08-14 Nicholas C. Henderson , Ravi Varadhan

In this paper, we analyze the convergence %semi-convergence properties of projected non-stationary block iterative methods (P-BIM) aiming to find a constrained solution to large linear, usually both noisy and ill-conditioned, systems of…

Numerical Analysis · Mathematics 2022-02-11 Mahdi Mirzapour , Andrzej Cegielski , Tommy Elfving

Efficient feature selection from high-dimensional datasets is a very important challenge in many data-driven fields of science and engineering. We introduce a statistical mechanics inspired strategy that addresses the problem of sparse…

Machine Learning · Statistics 2021-04-07 Alfredo Braunstein , Thomas Gueudré , Andrea Pagnani , Mirko Pieropan

Finite mixture models are powerful tools for modelling and analyzing heterogeneous data. Parameter estimation is typically carried out using maximum likelihood estimation via the Expectation-Maximization (EM) algorithm. Recently, the…

Computation · Statistics 2020-05-15 Sharon X. Lee , Geoffrey J. McLachlan , Kaleb L. Leemaqz

Understanding elementary mechanisms behind solid-state phase transformations and reactions is the key to optimizing desired functional properties of many technologically relevant materials. Recent advances in scanning transmission electron…

Physical properties and functionalities of materials are dictated by global crystal structures as well as local defects. To establish a structure-property relationship, not only the crystallographic symmetry but also quantitative knowledge…