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The synaptic connectivity of cortex is plastic, with experience shaping the ongoing interactions between neurons. Theoretical studies of spike timing-dependent plasticity (STDP) have focused on either just pairs of neurons or large-scale…

Neurons and Cognition · Quantitative Biology 2016-08-02 Gabriel Koch Ocker , Brent Doiron

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Spiking Neural Networks (SNNs) emulate the integrated-fire-leak mechanism found in biological neurons, offering a compelling combination of biological realism and energy efficiency. In recent years, they have gained considerable research…

Neural and Evolutionary Computing · Computer Science 2024-06-06 Lihao Wang , Zhaofei Yu

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Adaptive behavior requires the brain to transition between distinct contexts while maintaining representations of prior experience. The ability to reconfigure neural representations without erasing previously acquired knowledge is central…

Neurons and Cognition · Quantitative Biology 2026-05-12 Qianqian Shi , Yue Che , Faqiang Liu , Hongyi Li , Mingkun Xu , Sandra Reinert , Pieter M. Goltstein , Rong Zhao , Luping Shi

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

Neurons and Cognition · Quantitative Biology 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

Spiking Neural Networks (SNNs) are promising candidates for low-power edge computing in domains such as wearable sensing and time-series analysis. A key neuronal parameter, the leaky time constant (LTC), governs temporal integration of…

Neural and Evolutionary Computing · Computer Science 2025-08-29 Chiu-Chang Cheng , Kapil Bhardwaj , Ya-Ning Chang , Sayani Majumdar , Chao-Hung Wang

Previous research has found that functional connectivity (FC) can accurately predict the identity of a subject performing a task and the type of task being performed. We replicate these results using a large dataset collected at the OSU…

Neurons and Cognition · Quantitative Biology 2018-07-13 Garren Gaut , Xiangrui Li , Brandon Turner , William A. Cunningham , Zhong-Lin Lu , Mark Steyvers

Dynamic functional connectivity (FC) has in recent years become a topic of interest in the neuroimaging community. Several models and methods exist for both functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), and…

Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

Edge time series are increasingly used in brain functional imaging to study the node functional connectivity (nFC) dynamics at the finest temporal resolution while avoiding sliding windows. Here, we lay the mathematical foundations for the…

Neurons and Cognition · Quantitative Biology 2022-07-15 Leonardo Novelli , Adeel Razi

The relation between spontaneous and stimulated global brain activity is a fundamental problem in the understanding of brain functions. This question is investigated both theoretically and experimentally within the context of nonequilibrium…

Neurons and Cognition · Quantitative Biology 2020-09-07 A. Sarracino , O. Arviv , O. Shriki , L. de Arcangelis

Temporal-network models have provided key insights into how time-varying connectivity shapes dynamical processes such as spreading. Among them, the activity-driven model is a widely used, analytically tractable benchmark. Yet many temporal…

Physics and Society · Physics 2025-11-20 Zsófia Simon , Jari Saramäki

Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition. While many methods have been proposed, reliably establishing the…

Methodology · Statistics 2019-10-30 Lingge Li , Dustin Pluta , Babak Shahbaba , Norbert Fortin , Hernando Ombao , Pierre Baldi

Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed…

Neurons and Cognition · Quantitative Biology 2022-07-19 Yan-Liang Shi , Roxana Zeraati , Anna Levina , Tatiana A. Engel

Dynamic functional connectivity analysis provides valuable information for understanding brain functional activity underlying different cognitive processes. Besides sliding window based approaches, a variety of methods have been developed…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Yong Fan

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Humans learn multiple tasks in succession with minimal mutual interference, through the context gating mechanism in the prefrontal cortex (PFC). The brain-inspired models of spiking neural networks (SNN) have drawn massive attention for…

Neural and Evolutionary Computing · Computer Science 2024-06-05 Jiangrong Shen , Wenyao Ni , Qi Xu , Gang Pan , Huajin Tang

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

To understand the biological characteristics of neurological disorders with functional connectivity (FC), recent studies have widely utilized deep learning-based models to identify the disease and conducted post-hoc analyses via explainable…

Machine Learning · Computer Science 2023-10-09 Eunsong Kang , Da-woon Heo , Jiwon Lee , Heung-Il Suk
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