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Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nils Hampe , Sanne G. M. van Velzen , Jean-Paul Aben , Carlos Collet , Ivana Išgum

Coronary Artery Disease (CAD) is one of the most common forms of heart disease, which is caused by a buildup of atherosclerotic plaque (known as stenosis) in the coronary arteries, leading to insufficient supplement of blood, oxygen, and…

Computational Engineering, Finance, and Science · Computer Science 2024-09-06 Haizhou Yang , C. Alberto Figueroa , Krishna Garikipati

Coronary angiography is the main tool for assessing coronary artery disease, but visual grading of stenosis is variable and only moderately related to ischaemia. Wire based fractional flow reserve (FFR) improves lesion selection but is not…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Georgy Kopanitsa , Oleg Metsker , Alexey Yakovlev

This paper explores the recent advancements in enhancing Computational Fluid Dynamics (CFD) tasks through Machine Learning (ML) techniques. We begin by introducing fundamental concepts, traditional methods, and benchmark datasets, then…

Blood flow is sensitive to disease and provides insight into cardiac function, making flow field analysis valuable for diagnosis. However, while safer than radiation-based imaging and more suitable for patients with medical implants,…

Machine Learning · Computer Science 2025-11-04 Viraj Patel , Lisa Kreusser , Katharine Fraser

Purpose of Review Recently, machine learning has developed rapidly in the field of medicine, playing an important role in disease diagnosis. Our aim of this paper is to provide an overview of the advancements in machine learning techniques…

Medical Physics · Physics 2024-05-15 Pukar Baral , Chen Zhao , Michele Esposito , Weihua Zhou

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

Coronary artery disease (CAD) is one of the most common causes of death in the European Union and the USA. The crucial biomarker in its diagnosis is called Fractional Flow Reserve (FFR) and its in-vivo measurement is obtained via an…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Patryk Rygiel

Establishing patient-specific finite element analysis (FEA) models for computational fluid dynamics (CFD) of double stenosed artery models involves time and effort, restricting physicians' ability to respond quickly in time-critical medical…

Medical Physics · Physics 2022-02-18 Ishat Raihan Jamil , Mayeesha Humaira

Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

Medical Physics · Physics 2025-07-01 Oeshee Roy , Priyanshu Ghosh , Sayan Karmakar , Supratim Saha

The transformative impact of machine learning, particularly Deep Learning (DL), on scientific and engineering domains is evident. In the context of computational fluid dynamics (CFD), Physics-Informed Neural Networks (PINNs) represent a…

Fluid Dynamics · Physics 2024-04-05 Siddharth Raghu , Rajdip Nayek , Vamsi Chalamalla

Computational fluid dynamics (CFD) can be used to simulate vascular haemodynamics and analyse potential treatment options. CFD has shown to be beneficial in improving patient outcomes. However, the implementation of CFD for routine clinical…

Background: Non-invasive imaging-based assessment of blood flow plays a critical role in evaluating heart function and structure. Computed Tomography (CT) is a widely-used imaging modality that can robustly evaluate cardiovascular anatomy…

Image and Video Processing · Electrical Eng. & Systems 2025-11-07 Jinyuxuan Guo , Gurnoor Singh Khurana , Alejandro Gonzalo Grande , Juan C. del Alamo , Francisco Contijoch

Coronary artery disease, caused by the narrowing of coronary vessels due to atherosclerosis, is the leading cause of death worldwide. The diagnostic gold standard, fractional flow reserve (FFR), measures the trans-stenotic pressure ratio…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Guido Nannini , Julian Suk , Patryk Rygiel , Simone Saitta , Luca Mariani , Riccardo Maragna , Andrea Baggiano , Gianluca Pontone , Jelmer M. Wolterink , Alberto Redaelli

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Due to the limited accuracy of 4D Magnetic Resonance Imaging (MRI) in identifying hemodynamics in cardiovascular diseases, the challenges in obtaining patient-specific flow boundary conditions, and the computationally demanding and…

Machine Learning · Computer Science 2025-03-25 Oscar L. Cruz-González , Valérie Deplano , Badih Ghattas

Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

Machine Learning · Computer Science 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

Dynamic magnetic resonance imaging (dMRI) captures temporally-resolved anatomy but is often challenged by limited sampling and motion-induced artifacts. Conventional motion-compensated reconstructions typically rely on pre-estimated optical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Baoqing Li , Yuanyuan Liu , Congcong Liu , Qingyong Zhu , Jing Cheng , Yihang Zhou , Hao Chen , Zhuo-Xu Cui , Dong Liang

Machine learning-based approaches outperform competing methods in most disciplines relevant to diagnostic radiology. Interventional radiology, however, has not yet benefited substantially from the advent of deep learning, in particular…

Computationally efficient and accurate simulations of the flow over axisymmetric bodies of revolution (ABR) has been an important desideratum for engineering design. In this article the flow field over an ABR is predicted using machine…

Fluid Dynamics · Physics 2021-11-16 J P Panda , H V Warrior
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