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Replicating the computational functionalities and performances of the brain remains one of the biggest challenges for the future of information and communication technologies. Such an ambitious goal requires research efforts from the…

Biological Physics · Physics 2015-05-20 Selina La Barbera , Dominique Vuillaume , Fabien Alibart

Understanding how biological neural networks carry out learning using spike-based local plasticity mechanisms can lead to the development of powerful, energy-efficient, and adaptive neuromorphic processing systems. A large number of…

Neural and Evolutionary Computing · Computer Science 2022-11-08 Lyes Khacef , Philipp Klein , Matteo Cartiglia , Arianna Rubino , Giacomo Indiveri , Elisabetta Chicca

Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain's neural networks. A central question is how synapses, with access to only local information about the network, can still organize collectively and…

Neural and Evolutionary Computing · Computer Science 2019-12-06 Dina Obeid , Hugo Ramambason , Cengiz Pehlevan

In recent years, machine learning has demonstrated impressive capability in handling molecular science tasks. To support various molecular properties at scale, machine learning models are trained in the multi-task learning paradigm.…

Machine Learning · Computer Science 2024-10-15 Yuxuan Ren , Dihan Zheng , Chang Liu , Peiran Jin , Yu Shi , Lin Huang , Jiyan He , Shengjie Luo , Tao Qin , Tie-Yan Liu

The adaptive changes in synaptic efficacy that occur between spiking neurons have been demonstrated to play a critical role in learning for biological neural networks. Despite this source of inspiration, many learning focused applications…

Neural and Evolutionary Computing · Computer Science 2022-05-30 Samuel Schmidgall , Julia Ashkanazy , Wallace Lawson , Joe Hays

Elasto-plastic models are among the most successful ways to study the critical properties of the plastic yielding transition of amorphous solids. Typically these models are studied under a condition of constant transition rates from one…

Statistical Mechanics · Physics 2017-12-05 E. A. Jagla

The minimum energy, and, more generally, the minimum cost, to transmit one bit of information has been recently derived for bursty communication when information is available infrequently at random times at the transmitter. This result…

Information Theory · Computer Science 2013-03-25 Aslan Tchamkerten , Venkat Chandar , Giuseppe Caire

The synaptic connectivity of cortical networks features an overrepresentation of certain wiring motifs compared to simple random-network models. This structure is shaped, in part, by synaptic plasticity that promotes or suppresses…

Neurons and Cognition · Quantitative Biology 2014-12-23 Gabriel Koch Ocker , Ashok Litwin-Kumar , Brent Doiron

Dispatchability of renewable energy sources and inflexible loads can be achieved using a volatility-compensating energy storage. However, as the future power outputs of the inflexible devices are uncertain, the computation of a dispatch…

Systems and Control · Computer Science 2018-05-25 R. R. Appino , J. Á. González Ordiano , R. Mikut , V. Hagenmeyer , T. Faulwasser

Humans effortlessly navigate the physical world by predicting how objects behave under gravity and contact forces, yet how such judgments support sequential physical planning under resource constraints remains poorly understood. Research on…

Artificial Intelligence · Computer Science 2026-04-13 Ruihong Shen , Shiqian Li , Yixin Zhu

It has recently been shown that the average energy required to control a subset of nodes in a complex network scales exponentially with the cardinality of the subset. While the mean scales exponentially, the variance of the control energy…

Physics and Society · Physics 2018-08-23 Isaac Klickstein , Francesco Sorrentino

There is evidence that biological synapses have only a fixed number of discrete weight states. Memory storage with such synapses behaves quite differently from synapses with unbounded, continuous weights as old memories are automatically…

Neurons and Cognition · Quantitative Biology 2008-03-14 Adam B. Barrett , M. C. W. van Rossum

Recent animal studies have shown that biological brains can enter a low power mode in times of food scarcity. This paper explores the possibility of applying similar mechanisms to a broad class of neuromorphic systems where power…

Neural and Evolutionary Computing · Computer Science 2023-06-14 Cory Merkel

Short-term presynaptic plasticity designates variations of the amplitude of synaptic information transfer whereby the amount of neurotransmitter released upon presynaptic stimulation changes over seconds as a function of the neuronal firing…

Neurons and Cognition · Quantitative Biology 2011-12-06 Maurizio De Pittà , Vladislav Volman , Hugues Berry , Eshel Ben-Jacob

Modern machine learning optimizes for accuracy without explicit treatment of internal computational cost, even though physical and biological systems operate under intrinsic energy constraints. We evaluate energy-aware learning across 2,203…

Machine Learning · Computer Science 2026-05-01 Martin G. Frasch

Living cells deploy many resources to sense their environments, including receptors, downstream signaling molecules, time and fuel. However, it is not known which resources fundamentally limit the precision of sensing, like weak links in a…

Molecular Networks · Quantitative Biology 2014-01-31 Christopher C. Govern , Pieter Rein ten Wolde

In the absence of external driving, a system exposed to thermal fluctuations will relax to equilibrium. However, the constant input of work makes it possible to counteract this relaxation, and maintain the system in a nonequilibrium steady…

Statistical Mechanics · Physics 2017-07-04 Jordan M. Horowitz , Kevin Zhou , Jeremy L. England

In the mammalian nervous system, various synaptic plasticity rules act, either individually or synergistically, and over wide-ranging timescales to dictate the processes that enable learning and memory formation. To mimic biological…

Disordered Systems and Neural Networks · Physics 2021-06-11 Syed Ghazi Sarwat , Benedikt Kersting , Timoleon Moraitis , Vara Prasad Jonnalagadda , Abu Sebastian

Information processing machines at the nanoscales are unavoidably affected by thermal fluctuations. Efficient design requires understanding how nanomachines can operate at minimal energy dissipation. In this letter we focus on mechanical…

Statistical Mechanics · Physics 2015-03-17 Paolo Muratore-Ginanneschi , Kay Schwieger

As the penetration level of transmission-scale time-intermittent renewable generation resources increases, control of flexible resources will become important to mitigating the fluctuations due to these new renewable resources. Flexible…

Optimization and Control · Mathematics 2013-09-12 Krishnamurthy Dvijotham , Scott Backhaus , Misha Chertkov
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