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Predicting drug-induced cellular state changes at single-cell resolution remains a central challenge in virtual cell modeling, particularly under out-of-distribution (OOD) conditions. Current approaches predominantly rely on RNA-based…

Genomics · Quantitative Biology 2026-05-18 Peiting Shi , Ningfeng Que , Xianzhe Huang , Xiaofei Wang , Jianzhong Jeff Xi

A critical challenge for reinforcement learning (RL) is making decisions based on incomplete and noisy observations, especially in perturbed and partially observable Markov decision processes (P$^2$OMDPs). Existing methods fail to mitigate…

Machine Learning · Computer Science 2025-12-02 Na Li , Hangguan Shan , Wei Ni , Wenjie Zhang , Xinyu Li , Yamin Wang

Belief propagation is an algorithm that is known from statistical physics and computer science. It provides an efficient way of calculating marginals that involve large sums of products which are efficiently rearranged into nested products…

Artificial Intelligence · Computer Science 2020-12-22 Tim Ritmeester , Hildegard Meyer-Ortmanns

Diffusion models achieve great success in generating diverse and high-fidelity images, yet their widespread application, especially in real-time scenarios, is hampered by their inherently slow generation speed. The slow generation stems…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Shengkun Tang , Yaqing Wang , Caiwen Ding , Yi Liang , Yao Li , Dongkuan Xu

The development of video diffusion models unveils a significant challenge: the substantial computational demands. To mitigate this challenge, we note that the reverse process of diffusion exhibits an inherent entropy-reducing nature. Given…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Lingmin Ran , Mike Zheng Shou

In this work, we explore an untapped signal in diffusion model inference. While all previous methods generate images independently at inference, we instead ask if samples can be generated collaboratively. We propose Group Diffusion,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Sicheng Mo , Thao Nguyen , Richard Zhang , Nick Kolkin , Siddharth Srinivasan Iyer , Eli Shechtman , Krishna Kumar Singh , Yong Jae Lee , Bolei Zhou , Yuheng Li

Effective coordination of agents actions in partially-observable domains is a major challenge of multi-agent systems research. To address this, many researchers have developed techniques that allow the agents to make decisions based on…

Multiagent Systems · Computer Science 2011-09-28 P. S. Dutta , N. R. Jennings , L. Moreau

We propose a novel diffusion-based image generation method called the observation-guided diffusion probabilistic model (OGDM), which effectively addresses the tradeoff between quality control and fast sampling. Our approach reestablishes…

Machine Learning · Computer Science 2024-04-02 Junoh Kang , Jinyoung Choi , Sungik Choi , Bohyung Han

World models have recently gained prominence for action-conditioned visual prediction in complex environments. However, relying on only a few recent observations causes them to lose long-term context. Consequently, within a few steps, the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Nedko Savov , Naser Kazemi , Deheng Zhang , Danda Pani Paudel , Xi Wang , Luc Van Gool

Object detection is a critical task in computer vision, with applications in various domains such as autonomous driving and urban scene monitoring. However, deep learning-based approaches often demand large volumes of annotated data, which…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Hao Li , Xiangyuan Yang , Mengzhu Wang , Long Lan , Ke Liang , Xinwang Liu , Kenli Li

The distributed coordination of robot teams performing complex tasks is challenging to formulate. The different aspects of a complete task such as local planning for obstacle avoidance, global goal coordination and collaborative mapping are…

Robotics · Computer Science 2023-10-04 Aalok Patwardhan , Andrew J. Davison

The study of continuous-time information diffusion has been an important area of research for many applications in recent years. When only the diffusion traces (cascades) are accessible, cascade-based network inference and influence…

Social and Information Networks · Computer Science 2024-05-22 Keke Huang , Ruize Gao , Bogdan Cautis , Xiaokui Xiao

Global Navigation Satellite Systems (GNSS) are vital for reliable urban positioning. However, multipath and non-line-of-sight reception often introduce large measurement errors that degrade accuracy. Learning-based methods for predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Jiaqi Zhu , Shouyi Lu , Ziyao Li , Guirong Zhuo , Lu Xiong

Most works on multi-agent reinforcement learning focus on scenarios where the state of the environment is fully observable. In this work, we consider a cooperative policy evaluation task in which agents are not assumed to observe the…

Machine Learning · Computer Science 2023-05-17 Mert Kayaalp , Fatima Ghadieh , Ali H. Sayed

Many real-world decision problems involve the interaction of multiple self-interested agents with limited sensing ability. The partially observable stochastic game (POSG) provides a mathematical framework for modeling these problems,…

Computer Science and Game Theory · Computer Science 2024-10-30 Tyler Becker , Zachary Sunberg

Denoising diffusion probabilistic models (DDPMs) have achieved impressive performance on various image generation tasks, including image super-resolution. By learning to reverse the process of gradually diffusing the data distribution into…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Kai Zhao , Alex Ling Yu Hung , Kaifeng Pang , Haoxin Zheng , Kyunghyun Sung

Distributed sensor networks often include a multitude of sensors, each measuring parts of a process state space or observing the operations of a system. Communication of measurements between the sensor nodes and estimator(s) cannot…

Systems and Control · Electrical Eng. & Systems 2023-05-02 Sanjay Chandrasekaran , Vishnu Varadan , Siva Vignesh Krishnan , Florian Dörfler , Mohammad H. Mamduhi

Uncertainty pervades through the modern robotic autonomy stack, with nearly every component (e.g., sensors, detection, classification, tracking, behavior prediction) producing continuous or discrete probabilistic distributions. Trajectory…

Robotics · Computer Science 2022-07-13 Boris Ivanovic , Yifeng Lin , Shubham Shrivastava , Punarjay Chakravarty , Marco Pavone

This paper deals with the state estimation of linear time-invariant systems using distributed observers with local sampled-data measurement and aperiodic communication. Each observer agent perceives partial information of the system to be…

Systems and Control · Electrical Eng. & Systems 2024-06-11 Shimin Wang , Ya-Jun Pan , Martin Guay

Recent innovations in diffusion probabilistic models have paved the way for significant progress in image, text and audio generation, leading to their applications in generative time series forecasting. However, leveraging such abilities to…

Machine Learning · Computer Science 2025-11-07 Yuansan Liu , Sudanthi Wijewickrema , Dongting Hu , Christofer Bester , Stephen O'Leary , James Bailey