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Chronic diseases constitute the principal burden of morbidity, mortality, and healthcare costs worldwide, yet current health systems remain fragmented and predominantly reactive. Patient Medical Digital Twins (PMDTs) offer a paradigm shift:…

Software Engineering · Computer Science 2026-02-13 Micheal P. Papazoglou , Bernd J. Krämer , Mira Raheem , Amal Elgammal

Digital twins (DTs) are redefining healthcare by paving the way for more personalized, proactive, and intelligent medical interventions. As the shift toward personalized care intensifies, there is a growing need for an individual's virtual…

Human-Computer Interaction · Computer Science 2025-03-18 Melvin Mokhtari

Modern supercomputers can handle resource-intensive computational and data-driven problems in various industries and academic fields. These supercomputers are primarily made up of traditional classical resources comprising CPUs and GPUs.…

Quantum Physics · Physics 2024-11-01 Soronzonbold Otgonbaatar , Elise Jennings

The convergence of digital twin technology and quantum computing is opening new horizons for the modeling, control, and optimization of smart grid systems. This paper reviews the current research landscape at the intersection of these…

Quantum Physics · Physics 2025-08-27 Arianne Ornella Lemo , Ahmad Mohammad Saber , Deepa Kundur , Adam W. Skorek

With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

Digital Twins (DTs) are virtual representations of physical objects or processes that can collect information from the real environment to represent, validate, and replicate the physical twin's present and future behavior. The DTs are…

Networking and Internet Architecture · Computer Science 2023-05-26 S M Mostaq Hossain , Sohag Kumar Saha , Shampa Banik , Trapa Banik

Human digital twins (HDTs) are dynamic, data-driven virtual representations of individuals, continuously updated with multimodal data to simulate, monitor, and predict health trajectories. By integrating clinical, physiological, behavioral,…

Human-Computer Interaction · Computer Science 2025-08-19 Rong Pan , Hongyue Sun , Xiaoyu Chen , Giulia Pedrielli , Jiapeng Huang

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

The adoption of digital twins (DTs) in precision medicine is increasingly viable, propelled by extensive data collection and advancements in artificial intelligence (AI), alongside traditional biomedical methodologies. However, the reliance…

As the population grows, the need for a quality level of medical services grows correspondingly, so does the demand for information technology in medicine. The concept of "Smart Healthcare" offers many approaches aimed at solving the acute…

Computers and Society · Computer Science 2021-06-23 Ivan Volkov , Gleb Radchenko , Andrey Tchernykh

Digital Twin (DT) has gained great interest as an innovative technology in Industry 4.0 that enables advanced modeling, simulation, and optimization of service and manufacturing systems. This article provides an extensive review of the…

General Mathematics · Mathematics 2026-01-26 Sarow Saeedi

Digital Twins (DTs) are virtual representations of physical systems synchronized in real time through Internet of Things (IoT) sensors and computational models. In industrial applications, DTs enable predictive maintenance, fault diagnosis,…

Other Computer Science · Computer Science 2025-07-18 Ali Mohammad-Djafari

Digital twin (DT) is the recurrent and common feature in discussions about future technologies, bringing together advanced communication, computation, and artificial intelligence, to name a few. In the context of Industry 4.0, industries…

Cryptography and Security · Computer Science 2023-12-29 Kunlun Wang , Yongyi Tang , Trung Q. Duong , Saeed R. Khosravirad , Octavia A. Dobre , George K. Karagiannidis

A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health…

Artificial Intelligence · Computer Science 2024-04-24 Chenyu Tang , Wentian Yi , Edoardo Occhipinti , Yanning Dai , Shuo Gao , Luigi G. Occhipinti

Digital twin (DT) is one of the most promising enabling technologies for realizing smart grids. Characterized by seamless and active---data-driven, real-time, and closed-loop---integration between digital and physical spaces, a DT is much…

Signal Processing · Electrical Eng. & Systems 2019-09-17 Xing He , Qian Ai , Robert C. Qiu , Dongxia Zhang

Digital twin technology has is anticipated to transform healthcare, enabling personalized medicines and support, earlier diagnoses, simulated treatment outcomes, and optimized surgical plans. Digital twins are readily gaining traction in…

Machine Learning · Computer Science 2023-07-12 Logan Nye

This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer patient prognosis through personalized radiopharmaceutical…

Other Quantitative Biology · Quantitative Biology 2025-11-07 Marc Ryhiner , Yangmeihui Song , Babak Saboury , Gerhard Glatting , Arman Rahmim , Kuangyu Shi

A digital health twin can be defined as a virtual model of a physical person, in this specific case, a patient. This virtual model is constituted by multidimensional data that can host from clinical, molecular and therapeutic parameters to…

Computers and Society · Computer Science 2022-12-02 Manuel Cossio

Quantum computing promises to revolutionize several scientific and technological domains through fundamentally new ways of processing information. Among its most compelling applications is digital quantum simulation, where quantum computers…

Quantum Physics · Physics 2026-02-05 Laurin E. Fischer

Digital Twin was introduced over a decade ago, as an innovative all-encompassing tool, with perceived benefits including real-time monitoring, simulation and forecasting. However, the theoretical framework and practical implementations of…

Machine Learning · Computer Science 2020-12-07 Angira Sharma , Edward Kosasih , Jie Zhang , Alexandra Brintrup , Anisoara Calinescu
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