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Related papers: MB-DSMIL-CL-PL: Scalable Weakly Supervised Ovarian…

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Weakly-supervised learning (WSL) has recently triggered substantial interest as it mitigates the lack of pixel-wise annotations. Given global image labels, WSL methods yield pixel-level predictions (segmentations), which enable to interpret…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

In this paper we apply computer learning methods to diagnosing ovarian cancer using the level of the standard biomarker CA125 in conjunction with information provided by mass-spectrometry. We are working with a new data set collected over a…

Artificial Intelligence · Computer Science 2009-04-10 Fedor Zhdanov , Vladimir Vovk , Brian Burford , Dmitry Devetyarov , Ilia Nouretdinov , Alex Gammerman

Cytology is a valuable tool for early detection of oral squamous cell carcinoma (OSCC). However, manual examination of cytology whole slide images (WSIs) is slow, subjective, and depends heavily on expert pathologists. To address this, we…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Rupam Mukherjee , Rajkumar Daniel , Soujanya Hazra , Shirin Dasgupta , Subhamoy Mandal

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Adrien Nivaggioli , Nicolas Pozin , Rémy Peyret , Stéphane Sockeel , Marie Sockeel , Nicolas Nerrienet , Marceau Clavel , Clara Simmat , Catherine Miquel

Recent advances in self-supervised learning (SSL) have largely closed the gap with supervised ImageNet pretraining. Despite their success these methods have been primarily applied to unlabeled ImageNet images, and show marginal gains when…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Ramprasaath R. Selvaraju , Karan Desai , Justin Johnson , Nikhil Naik

The rapidly evolving field of digital oncopathology faces significant challenges, including the need to address diverse and complex clinical questions, often involving rare conditions, with limited availability of labeled data. These…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Jonathan Zalach , Inbal Gazy , Assaf Avinoam , Ron Sinai , Eran Shmuel , Inbar Gilboa , Christine Swisher , Naim Matasci , Reva Basho , David B. Agus

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Linghan Cai , Shenjin Huang , Ye Zhang , Jinpeng Lu , Yongbing Zhang

Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Manu Goyal , Laura J. Tafe , James X. Feng , Kristen E. Muller , Liesbeth Hondelink , Jessica L. Bentz , Saeed Hassanpour

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Zheren Li , Zhiming Cui , Lichi Zhang , Sheng Wang , Chenjin Lei , Xi Ouyang , Dongdong Chen , Xiangyu Zhao , Yajia Gu , Zaiyi Liu , Chunling Liu , Dinggang Shen , Jie-Zhi Cheng

Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Cervical cancer is one of the deadliest cancers affecting women globally. Cervical intraepithelial neoplasia (CIN) assessment using histopathological examination of cervical biopsy slides is subject to interobserver variability. Automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Sudhir Sornapudi , R. Joe Stanley , William V. Stoecker , Rodney Long , Zhiyun Xue , Rosemary Zuna , Shelliane R. Frazier , Sameer Antani

The most prevalent form of bladder cancer is urothelial carcinoma, characterized by a high recurrence rate and substantial lifetime treatment costs for patients. Grading is a prime factor for patient risk stratification, although it suffers…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Saul Fuster , Umay Kiraz , Trygve Eftestøl , Emiel A. M. Janssen , Kjersti Engan

Automated digital histopathology image segmentation is an important task to help pathologists diagnose tumors and cancer subtypes. For pathological diagnosis of cancer subtypes, pathologists usually change the magnification of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2019-04-15 Hiroki Tokunaga , Yuki Teramoto , Akihiko Yoshizawa , Ryoma Bise

This study introduces a federated learning-based approach to predict HER2 status from hematoxylin and eosin (HE)-stained whole slide images (WSIs), reducing costs and speeding up treatment decisions. To address label imbalance and feature…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Kamorudeen A. Amuda , Almustapha A. Wakili

In recent years, the integration of advanced imaging techniques and deep learning methods has significantly advanced computer-aided diagnosis (CAD) systems for breast cancer detection and classification. Transformers, which have shown great…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Mahtab Ranjbar , Mehdi Mohebbi , Mahdi Cherakhloo , Bijan Vosoughi. Vahdat

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Mid-infrared spectroscopic imaging (MIRSI) is an emerging class of label-free techniques being leveraged for digital histopathology. Modern histopathologic identification of ovarian cancer involves tissue staining followed by morphological…

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