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The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

We assess the potential of quantum computing to accelerate computation of central tasks in genomics, focusing on often-neglected theoretical limitations. We discuss state-of-the-art challenges of quantum search, optimization, and machine…

Quantum Physics · Physics 2026-01-09 Aurora Maurizio , Guglielmo Mazzola

In recent years, quantum, quantum-inspired, and hybrid algorithms are increasingly showing promise for solving software engineering optimization problems. However, best-intended practices for conducting empirical studies have not yet well…

Software Engineering · Computer Science 2025-11-03 Man Zhang , Yuechen Li , Tao Yue , Kai-Yuan Cai

Hybrid solvers for combinatorial optimization problems combine the advantages of classical and quantum computing to overcome difficult computational challenges. Although their theoretical performance seems promising, their practical…

Quantum Physics · Physics 2025-07-14 Domenik Eichhorn , Nick Poser , Maximilian Schweikart , Ina Schaefer

Quantum computing is emerging as a new computing resource that could be superior to conventional computing for certain classes of optimization problems. However, in principle, most existing approaches to quantum optimization are intended to…

Optimization and Control · Mathematics 2022-01-21 Chin-Yao Chang , Eric Jones , Yiyun Yao , Peter Graf , Rishabh Jain

Quantum algorithms have the potential to provide exponential speedups over some of the best known classical algorithms. These speedups may enable quantum devices to solve currently intractable problems such as those in the fields of…

Quantum Physics · Physics 2018-12-13 Ciarán Ryan-Anderson

Quantum computing is rapidly emerging as a promising technology for solving complex optimization problems that arise in various engineering fields. Therefore, it holds significant promise to transform the computational foundations of power…

Quantum Physics · Physics 2026-01-06 Nikolaos G. Paterakis , Petros Karamanakos , Corey O'Meara , Georgios Papafotiou

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

Quantum computing has the potential to revolutionize multiple fields by solving complex problems that can not be solved in reasonable time with current classical computers. Nevertheless, the development of quantum computers is still in its…

Quantum algorithms can be analyzed in a query model to compute Boolean functions where input is given in a black box, but the aim is to compute function value for arbitrary input using as few queries as possible. In this paper we…

Quantum Physics · Physics 2012-03-24 Alina Dubrovska Vasilieva , Taisia Mischenko-Slatenkova

When trying to use quantum-enhanced methods for optimization problems, the sheer number of options inhibits its adoption by industrial end users. Expert knowledge is required for the formulation and encoding of the use case, the selection…

Quantum Physics · Physics 2025-05-27 Benedikt Poggel , Xiomara Runge , Adelina Bärligea , Jeanette Miriam Lorenz

Through recent progress in hardware development, quantum computers have advanced to the point where benchmarking of (heuristic) quantum algorithms at scale is within reach. Particularly in combinatorial optimization - where most algorithms…

The increasing growth of data volume, and the consequent explosion in demand for computational power, are affecting scientific computing, as shown by the rise of extreme data scientific workflows. As the need for computing power increases,…

Emerging Technologies · Computer Science 2024-04-17 Sandeep Suresh Cranganore , Vincenzo De Maio , Ivona Brandic , Ewa Deelman

Today's quantum computers are primarily accessible through the cloud and potentially shifting to the edge network in the future. With the rapid advancement and proliferation of quantum computing research worldwide, there has been a…

Quantum Physics · Physics 2023-11-09 Hoa T. Nguyen , Muhammad Usman , Rajkumar Buyya

Quantum computing provides computational advantages in various domains. To benefit from these advantages complex hybrid quantum applications must be built, which comprise both quantum and classical programs. Engineering these applications…

Quantum optimisation is emerging as a promising approach alongside classical heuristics and specialised hardware, yet its performance is often difficult to assess fairly. Traditional benchmarking methods, rooted in digital complexity…

Quantum Physics · Physics 2025-12-10 Frank Phillipson

Recent advances in quantum computing have sparked excitement that this new computing paradigm could solve previously intractable problems. However, due to the faulty nature of current quantum hardware and quantum-intrinsic noise, the full…

Software Engineering · Computer Science 2024-12-16 Jake Zappin , Trevor Stalnaker , Oscar Chaparro , Denys Poshyvanyk

The digital transformation that Telecommunications and ICT domains are crossing today, is posing several new challenges to Telecom Operators. These challenges require solving complex problems such as: dimensioning and scheduling of…

Quantum Physics · Physics 2022-05-04 Michele Amoretti , Davide Ferrari , Antonio Manzalini

The purpose of this paper is to explore the applications of quantum computing to energy systems optimization problems and discuss some of the challenges faced by quantum computers with techniques to overcome them. The basic concepts…

Quantum Physics · Physics 2020-03-03 Akshay Ajagekar , Fengqi You

Recent advancements in quantum computing are leading to an era of practical utility, enabling the tackling of increasingly complex problems. The goal of this era is to leverage quantum computing to solve real-world problems in fields such…

Quantum Physics · Physics 2025-05-07 Eneko Osaba , Esther Villar-Rodriguez , Izaskun Oregi