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We present a computational imaging mode for large scale electron microscopy data, which retrieves a complex wave from noisy/sparse intensity recordings using a deep learning approach and subsequently reconstructs an image of the specimen…

Materials Science · Physics 2022-02-28 Thomas Friedrich , Chu-Ping Yu , Johan Verbeek , Timothy Pennycook , Sandra Van Aert

Accurate determination of three-dimensional (3D) atomic structures is crucial for understanding and controlling the properties of nanomaterials. Atomic electron tomography (AET) offers non-destructive atomic imaging with picometer-level…

Materials Science · Physics 2025-06-23 Juhyeok Lee , Yongsoo Yang

Chemical transport models (CTMs), which simulate air pollution transport, transformation, and removal, are computationally expensive, largely because of the computational intensity of the chemical mechanisms: systems of coupled differential…

Atmospheric and Oceanic Physics · Physics 2018-08-14 Makoto M. Kelp , Christopher W. Tessum , Julian D. Marshall

In machine learning and molecular design, there exist two approaches: discriminative and generative. In the discriminative approach dubbed forward design, the goal is to map a set of features/molecules to their respective electronics…

Chemical Physics · Physics 2019-04-24 Alain Tchagang , Julio Valdés

Atomistic structures of materials offer valuable insights into their functionality. Determining these structures remains a fundamental challenge in materials science, especially for systems with defects. While both experimental and…

Materials Science · Physics 2025-01-16 Haili Jia , Yiming Chen , Gi-Hyeok Lee , Jacob Smith , Miaofang Chi , Wanli Yang , Maria K. Y. Chan

A complete characterization of the structure of nuclei can be obtained by combining information arising from inelastic scattering, Coulomb excitation and $\gamma-$decay, together with one- and two-particle transfer reactions. In this way it…

Nuclear Theory · Physics 2015-09-23 A. Idini , G. Potel , F. Barranco , E. Vigezzi , R. A. Broglia

Neural network potentials (NNPs) enable large-scale molecular dynamics (MD) simulations of systems containing >10,000 atoms with the accuracy comparable to ab initio methods and play a crucial role in material studies. Although NNPs are…

Quantum machine learning (QML) has great potential for the analysis of chemical datasets. However, conventional quantum data-encoding schemes, such as fingerprint encoding, are generally unfeasible for the accurate representation of…

Quantum Physics · Physics 2025-11-18 Choy Boy , Edoardo Altamura , Dilhan Manawadu , Ivano Tavernelli , Stefano Mensa , David J. Wales

Learning from data has led to paradigm shifts in a multitude of disciplines, including web, text, and image search, speech recognition, as well as bioinformatics. Can machine learning enable similar breakthroughs in understanding quantum…

Designing a network to learn a molecule structure given its physical/chemical properties is a hard problem, but is useful for drug discovery tasks. In this paper, we incorporate higher-order relational learning of Factor Graphs with strong…

Machine Learning · Computer Science 2020-12-11 Hieu Le Trung , Yiqing Xu , Wee Sun Lee

Retrosynthesis, which predicts the reactants of a given target molecule, is an essential task for drug discovery. In recent years, the machine learing based retrosynthesis methods have achieved promising results. In this work, we introduce…

Artificial Intelligence · Computer Science 2023-06-08 Shufang Xie , Rui Yan , Junliang Guo , Yingce Xia , Lijun Wu , Tao Qin

Encoding the electronic structure of molecules using 2-electron reduced density matrices (2RDMs) as opposed to many-body wave functions has been a decades-long quest as the 2RDM contains sufficient information to compute the exact molecular…

Chemical Physics · Physics 2022-08-11 David Pekker , Chungwen Liang , Sankha Pattanayak , Swagatam Mukhopadhyay

Fast and accurate structural dynamics analysis is important for structural design and damage assessment. Structural dynamics analysis leveraging machine learning techniques has become a popular research focus in recent years. Although the…

Geophysics · Physics 2020-12-29 Yuan Feng , Hexiang Wang , Han Yang , Fangbo Wang

Quantitative analysis of microstructural features on the nanoscale, including precipitates, local chemical orderings (LCOs) or structural defects (e.g. stacking faults) plays a pivotal role in understanding the mechanical and physical…

When modeling nuclear processes which occur in heavy-ion reactions, it is necessary to calculate the potential energy of interaction between two nuclei. One of the main features determining the dynamics of the nucleus-nucleus collision is…

Nuclear Theory · Physics 2023-11-16 Makar Simonov , Alexander Karpov , Tatiana Tretyakova

The precise reconstruction of properties of photons and electrons in modern high energy physics detectors, such as the CMS or Atlas experiments, plays a crucial role in numerous physics results. Conventional geometrical algorithms are used…

High Energy Physics - Experiment · Physics 2023-11-30 Polina Simkina , Fabrice Couderc , Julie Malclès , Mehmet Özgür Sahin

At its core, Quantum Mechanics is a theory developed to describe fundamental observations in the spectroscopy of solids and gases. Despite these practical roots, however, quantum theory is infamous for being highly counterintuitive, largely…

Quantum Physics · Physics 2020-01-20 Emmanuel Flurin , Leigh S. Martin , Shay Hacohen-Gourgy , Irfan Siddiqi

The study of structure-spectrum relationships is essential for spectral interpretation, impacting structural elucidation and material design. Predicting spectra from molecular structures is challenging due to their complex relationships.…

Computational Physics · Physics 2024-08-29 Fanjie Xu , Wentao Guo , Feng Wang , Lin Yao , Hongshuai Wang , Fujie Tang , Zhifeng Gao , Linfeng Zhang , Weinan E , Zhong-Qun Tian , Jun Cheng

Isomerization, i.e. the rearrangement between distinct molecular configurations, is a fundamental process in chemistry. Here we demonstrate that two-dimensional Coulomb crystals can emulate molecular isomerization and be used to…

Atomic Physics · Physics 2025-08-11 Naoto Mizukami , Gabriele Gatta , Lucia Duca , Carlo Sias

We have developed a deep learning algorithm for chemical shift prediction for atoms in molecular crystals that utilizes an atom-centered Gaussian density model for the 3D data representation of a molecule. We define multiple channels that…