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Recent advances in deep learning structured state space models, especially the Mamba architecture, have demonstrated remarkable performance improvements while maintaining linear complexity. In this study, we introduce functional…

Machine Learning · Computer Science 2025-03-24 Yuxiang Wei , Anees Abrol , Vince Calhoun

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Recent advances in deep learning have made it possible to predict phenotypic measures directly from functional magnetic resonance imaging (fMRI) brain volumes, sparking significant interest in the neuroimaging community. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Arunkumar Kannan , Martin A. Lindquist , Brian Caffo

In recent years, Visual Question Localized-Answering in robotic surgery (Surgical-VQLA) has gained significant attention for its potential to assist medical students and junior doctors in understanding surgical scenes. Recently, the rapid…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Pengfei Hao , Hongqiu Wang , Shuaibo Li , Zhaohu Xing , Guang Yang , Kaishun Wu , Lei Zhu

Accurate prediction of RNA-associated interactions is essential for understanding cellular regulation and advancing drug discovery. While Biological Large Language Models (BioLLMs) such as ESM-2 and RiNALMo provide powerful sequence…

Genomics · Quantitative Biology 2026-02-27 Rabeya Tus Sadia , Qiang Ye , Qiang Cheng

Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…

Artificial Intelligence · Computer Science 2025-11-17 Tiantian He , An Zhao , Elinor Thompson , Anna Schroder , Ahmed Abdulaal , Frederik Barkhof , Daniel C. Alexander

We introduce CausalMamba, a scalable framework that addresses fundamental limitations in fMRI-based causal inference: the ill-posed nature of inferring neural causality from hemodynamically distorted BOLD signals and the computational…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Sangyoon Bae , Jiook Cha

Attention mechanisms have been widely used to capture long-range dependencies among nodes in Graph Transformers. Bottlenecked by the quadratic computational cost, attention mechanisms fail to scale in large graphs. Recent improvements in…

Machine Learning · Computer Science 2024-02-02 Chloe Wang , Oleksii Tsepa , Jun Ma , Bo Wang

Mimicking the real interaction trajectory in the inference of the world model has been shown to improve the sample efficiency of model-based reinforcement learning (MBRL) algorithms. Many methods directly use known state sequences for…

Machine Learning · Computer Science 2025-01-22 Qian He , Wenqi Liang , Chunhui Hao , Gan Sun , Jiandong Tian

Neuroscience employs diverse neuroimaging techniques, each offering distinct insights into brain activity, from electrophysiological recordings such as EEG, which have high temporal resolution, to hemodynamic modalities such as fMRI, which…

Multimodal medical image fusion integrates complementary information from different imaging modalities to enhance diagnostic accuracy and treatment planning. While deep learning methods have advanced performance, existing approaches face…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Meng Zhou , Farzad Khalvati

Effective reasoning is crucial to solving complex mathematical problems. Recent large language models (LLMs) have boosted performance by scaling test-time computation through long chain-of-thought reasoning. However, transformer-based…

Machine Learning · Computer Science 2025-09-10 Junxiong Wang , Wen-Ding Li , Daniele Paliotta , Daniel Ritter , Alexander M. Rush , Tri Dao

Large Language Models have achieved remarkable success in language understanding and reasoning, and their multimodal extensions enable comprehension of images, video, and audio. Inspired by this, foundation models for brain functional…

Artificial Intelligence · Computer Science 2026-03-03 Xingcan Hu , Wei Wang , Li Xiao

The advancement of natural language processing (NLP) systems in healthcare hinges on language model ability to interpret the intricate information contained within clinical notes. This process often requires integrating information from…

Computation and Language · Computer Science 2024-03-12 Zhichao Yang , Avijit Mitra , Sunjae Kwon , Hong Yu

Accurate fMRI analysis requires sensitivity to temporal structure across multiple scales, as BOLD signals encode cognitive processes that emerge from fast transient dynamics to slower, large-scale fluctuations. Existing deep learning (DL)…

Signal Processing · Electrical Eng. & Systems 2026-01-06 Furkan Genç , Boran İsmet Macun , Sait Sarper Özaslan , Emine U. Saritas , Tolga Çukur

Multimodal large language models (MLLMs) have attracted widespread interest and have rich applications. However, the inherent attention mechanism in its Transformer structure requires quadratic complexity and results in expensive…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yanyuan Qiao , Zheng Yu , Longteng Guo , Sihan Chen , Zijia Zhao , Mingzhen Sun , Qi Wu , Jing Liu

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

Medical time series are central to healthcare, enabling continuous monitoring and supporting timely clinical decisions. Despite recent progress, existing methods struggle to jointly model local-global dynamics and handle nonstationarities…

Machine Learning · Computer Science 2026-05-26 Da Zhang , Bingyu Li , Zhiyuan Zhao , Hongyuan Zhang , Junyu Gao , Xuelong Li

Recent advances in multimodal large language models (LLMs) have enabled unified reasoning across images, audio, and video, but extending such capability to brain imaging remains largely unexplored. Bridging this gap is essential to link…

Computation and Language · Computer Science 2026-05-15 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Chengxuan Qian , Tianyang Wang , Vince D. Calhoun

Multimodal Large Language Models (MLLMs) have attracted much attention for their multifunctionality. However, traditional Transformer architectures incur significant overhead due to their secondary computational complexity. To address this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Wenjun Huang , Jiakai Pan , Jiahao Tang , Yanyu Ding , Yifei Xing , Yuhe Wang , Zhengzhuo Wang , Jianguo Hu
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