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We present three algorithms for calculating rate constants and sampling transition paths for rare events in simulations with stochastic dynamics. The methods do not require a priori knowledge of the phase space density and are suitable for…

Soft Condensed Matter · Physics 2009-11-11 Rosalind J. Allen , Daan Frenkel , Pieter Rein ten Wolde

Motivation: Many biochemical pathways are known, but the numerous parameters required to correctly explore the dynamics of the pathways are not known. For this reason, algorithms that can make inferences by looking at the topology of a…

Molecular Networks · Quantitative Biology 2009-07-23 Deepak Chandran , Herbert M. Sauro

For many tasks of data analysis, we may only have the information of the explanatory variable and the evaluation of the response values are quite expensive. While it is impractical or too costly to obtain the responses of all units, a…

Computation · Statistics 2023-04-07 Wei Zheng , Ting Tian , Xueqin Wang

Sampling from distributions of implicitly defined shapes enables analysis of various energy functionals used for image segmentation. Recent work describes a computationally efficient Metropolis-Hastings method for accomplishing this task.…

Computer Vision and Pattern Recognition · Computer Science 2012-05-17 Jason Chang , John W. Fisher

In the context of state-space models, skeleton-based smoothing algorithms rely on a backward sampling step which by default has a $\mathcal O(N^2)$ complexity (where $N$ is the number of particles). Existing improvements in the literature…

Computation · Statistics 2023-03-08 Hai-Dang Dau , Nicolas Chopin

Real-time path tracing increasingly operates under extremely low sampling budgets, often below one sample per pixel, as rendering complexity, resolution, and frame-rate requirements continue to rise. While super-resolution is widely used in…

Graphics · Computer Science 2026-02-10 Martin Bálint , Corentin Salaün , Hans-Peter Seidel , Karol Myszkowski

Path sampling allows the study of rare events like chemical reactions, nucleation and protein folding via a Monte Carlo (MC) exploration in path space. Instead of configuration points, this method samples short molecular dynamics (MD)…

Chemical Physics · Physics 2023-01-25 Daniel T. Zhang , Enrico Riccardi , Titus S. van Erp

During the last decade, sampling-based path planning algorithms, such as Probabilistic RoadMaps (PRM) and Rapidly-exploring Random Trees (RRT), have been shown to work well in practice and possess theoretical guarantees such as…

Robotics · Computer Science 2011-05-09 Sertac Karaman , Emilio Frazzoli

Inference and prediction of routes have become of interest over the past decade owing to a dramatic increase in package delivery and ride-sharing services. Given the underlying combinatorial structure and the incorporation of probabilities,…

Logic in Computer Science · Computer Science 2023-06-21 Suwei Yang , Victor C. Liang , Kuldeep S. Meel

In the context of the graph matching problem we propose a novel method for projecting a matrix $Q$, which may be a doubly stochastic matrix, to a permutation matrix $P.$ We observe that there is an intuitve mapping, depending on a given…

Applications · Statistics 2016-04-15 R. J. Wolstenholme , A. T. Walden

We give an efficient perfect sampling algorithm for weighted, connected induced subgraphs (or graphlets) of rooted, bounded degree graphs. Our algorithm utilizes a vertex-percolation process with a carefully chosen rejection filter and…

Data Structures and Algorithms · Computer Science 2023-11-17 Antonio Blanca , Sarah Cannon , Will Perkins

Analysis and design of filtered-x adaptive algorithms are conventionally done by assuming that the transfer function in the secondary path is a discrete-time system. However, in real systems such as active noise control, the secondary path…

Information Theory · Computer Science 2013-08-16 Masaaki Nagahara , Ken-ichi Hamaguchi , Yutaka Yamamoto

The computational study of conformational transitions in RNA and proteins with atomistic molecular dynamics often requires suitable enhanced sampling techniques. We here introduce a novel method where concurrent metadynamics are integrated…

Computational Physics · Physics 2015-09-01 Alejandro Gil-Ley , Giovanni Bussi

We present a novel, generally applicable Monte Carlo algorithm for the simulation of fluid systems. Geometric transformations are used to identify clusters of particles in such a manner that every cluster move is accepted, irrespective of…

Statistical Mechanics · Physics 2016-08-31 Jiwen Liu , Erik Luijten

Coordinate descent methods employ random partial updates of decision variables in order to solve huge-scale convex optimization problems. In this work, we introduce new adaptive rules for the random selection of their updates. By adaptive,…

Machine Learning · Computer Science 2017-03-08 Dmytro Perekrestenko , Volkan Cevher , Martin Jaggi

TAPAS is a novel adaptive sampling method for the softmax model. It uses a two pass sampling strategy where the examples used to approximate the gradient of the partition function are first sampled according to a squashed population…

Machine Learning · Computer Science 2017-07-17 Yu Bai , Sally Goldman , Li Zhang

Service providers employ different transport technologies like PDH, SDH/SONET, OTN, DWDM, Ethernet, MPLS-TP etc. to support different types of traffic and service requirements. Dynamic service provisioning requires the use of on-line…

Networking and Internet Architecture · Computer Science 2019-01-08 Madanagopal Ramachandran , Krishna M. Sivalingam

We introduce adaptive sampling methods for stochastic programs with deterministic constraints. First, we propose and analyze a variant of the stochastic projected gradient method where the sample size used to approximate the reduced…

Optimization and Control · Mathematics 2023-02-07 Florian Beiser , Brendan Keith , Simon Urbainczyk , Barbara Wohlmuth

A key overall goal of biomolecular simulations is the characterization of "mechanism" -- the pathways through configuration space of processes such as conformational transitions and binding. Some amount of heterogeneity is intrinsic to the…

Chemical Physics · Physics 2018-10-25 Ernesto Suárez , Daniel M. Zuckerman

In order to utilize network resources and provide a more reliable delivery of information, multipath routing algorithms are used with a higher priority than single path routing. But providing the quality of service (QoS) requirements while…

Networking and Internet Architecture · Computer Science 2014-12-09 Zahra Vali , Massoud Reza Hashemi , Neda Moghim