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We explore the relationship among model fidelity, experimental design, and parameter estimation in sloppy models. We show that the approximate nature of mathematical models poses challenges for experimental design in sloppy models. In many…

Quantitative Methods · Quantitative Biology 2017-02-08 Andrew White , Malachi Tolman , Howard D. Thames , Hubert Rodney Withers , Kathy A. Mason , Mark K. Transtrum

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Model ensembling is a well-established technique for improving the performance of machine learning models. Conventionally, this involves averaging the output distributions of multiple models and selecting the most probable label. This idea…

Machine Learning · Computer Science 2026-05-26 Jiale Fu , Yuchu Jiang , Peijun Wu , Chonghan Liu , Joey Tianyi Zhou , Xu Yang

The widespread adoption of large language models (LLMs) across industries has increased the demand for high-quality and customizable outputs. However, traditional alignment methods often require retraining large pretrained models, making it…

Computation and Language · Computer Science 2025-12-16 Yi Liu , Dianqing Liu , Mingye Zhu , Junbo Guo , Yongdong Zhang , Zhendong Mao

Cross-study replicability is a powerful model evaluation criterion that emphasizes generalizability of predictions. When training cross-study replicable prediction models, it is critical to decide between merging and treating the studies…

Machine Learning · Statistics 2022-07-14 Cathy Shyr , Pragya Sur , Giovanni Parmigiani , Prasad Patil

Model editing techniques are essential for efficiently updating knowledge in large language models (LLMs). However, the effectiveness of existing approaches degrades in massive editing scenarios, particularly when evaluated with practical…

Computation and Language · Computer Science 2026-02-25 Yanbo Dai , Zhenlan Ji , Zongjie Li , Shuai Wang

There is a long history in machine learning of model ensembling, beginning with boosting and bagging and continuing to the present day. Much of this history has focused on combining models for classification and regression, but recently…

Machine Learning · Computer Science 2024-05-28 Ira Globus-Harris , Varun Gupta , Michael Kearns , Aaron Roth

We tackle the challenge of feature embedding for the purposes of improving the click-through rate prediction process. We select three models: logistic regression, factorization machines and deep factorization machines, as our baselines and…

Machine Learning · Computer Science 2022-09-21 Samo Pahor , Davorin Kopič , Jure Demšar

The recent criticisms of the robustness of post hoc model approximation explanation methods (like LIME and SHAP) have led to the rise of model-precise abductive explanations. For each data point, abductive explanations provide a minimal…

Artificial Intelligence · Computer Science 2023-10-13 Gagan Biradar , Yacine Izza , Elita Lobo , Vignesh Viswanathan , Yair Zick

The trade-off between accuracy and interpretability has long been a challenge in machine learning (ML). This tension is particularly significant for emerging interpretable-by-design methods, which aim to redesign ML algorithms for…

Machine Learning · Computer Science 2025-05-28 Geyu Liang , Senne Michielssen , Salar Fattahi

Language models excel in various tasks by making complex decisions, yet understanding the rationale behind these decisions remains a challenge. This paper investigates \emph{data-centric interpretability} in language models, focusing on the…

Computation and Language · Computer Science 2025-06-10 Yuqian Li , Yupei Du , Yufang Liu , Feifei Feng , Mou Xiao Feng , Yuanbin Wu

Energy-based models (EBMs) are powerful probabilistic models, but suffer from intractable sampling and density evaluation due to the partition function. As a result, inference in EBMs relies on approximate sampling algorithms, leading to a…

Machine Learning · Computer Science 2020-01-10 Dieterich Lawson , George Tucker , Bo Dai , Rajesh Ranganath

A common approach for feature selection is to examine the variable importance scores for a machine learning model, as a way to understand which features are the most relevant for making predictions. Given the significance of feature…

Machine Learning · Computer Science 2021-05-13 Jack Dunn , Luca Mingardi , Ying Daisy Zhuo

Deep learning models have achieved remarkable success in different areas of machine learning over the past decade; however, the size and complexity of these models make them difficult to understand. In an effort to make them more…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Vikram V. Ramaswamy , Sunnie S. Y. Kim , Nicole Meister , Ruth Fong , Olga Russakovsky

In this paper we determine how multi-layer ensembling improves performance on multilingual intent classification. We develop a novel multi-layer ensembling approach that ensembles both different model initializations and different model…

Computation and Language · Computer Science 2018-06-22 Charles Costello , Ruixi Lin , Vishwas Mruthyunjaya , Bettina Bolla , Charles Jankowski

Predicting the effect of mutations in proteins is one of the most critical challenges in protein engineering; by knowing the effect a substitution of one (or several) residues in the protein's sequence has on its overall properties, could…

Computational Engineering, Finance, and Science · Computer Science 2020-10-08 David Medina-Ortiz , Sebastian Contreras , Juan Amado-Hinojosa , Jorge Torres-Almonacid , Juan A. Asenjo , Marcelo Navarrete , Álvaro Olivera-Nappa

Explanations in interactive machine-learning systems facilitate debugging and improving prediction models. However, the effectiveness of various global model-centric and data-centric explanations in aiding domain experts to detect and…

Artificial Intelligence · Computer Science 2024-02-02 Aditya Bhattacharya , Simone Stumpf , Lucija Gosak , Gregor Stiglic , Katrien Verbert

Unsupervised methods, such as wav2vec2 and HuBERT, have achieved state-of-the-art performance in audio tasks, leading to a shift away from research on interpretable features. However, the lack of interpretability in these methods limits…

Audio and Speech Processing · Electrical Eng. & Systems 2025-08-07 Yacouba Kaloga , Ina Kodrasi

We propose EBLIME to explain black-box machine learning models and obtain the distribution of feature importance using Bayesian ridge regression models. We provide mathematical expressions of the Bayesian framework and theoretical outcomes…

Machine Learning · Statistics 2023-05-02 Yuhao Zhong , Anirban Bhattacharya , Satish Bukkapatnam

As machine learning becomes increasingly integral to autonomous decision-making processes involving human interaction, the necessity of comprehending the model's outputs through conversational means increases. Most recently, foundation…

Artificial Intelligence · Computer Science 2024-07-31 Sule Tekkesinoglu , Lars Kunze