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Reinforcement learning from human feedback (RLHF) has emerged as a powerful technique to make large language models (LLMs) more capable in complex settings. RLHF proceeds as collecting human preference data, training a reward model on said…

Machine Learning · Computer Science 2024-02-05 Nathan Lambert , Roberto Calandra

Medical automatic diagnosis aims to imitate human doctors in real-world diagnostic processes and to achieve accurate diagnoses by interacting with the patients. The task is formulated as a sequential decision-making problem with a series of…

Machine Learning · Computer Science 2022-06-07 Hongyi Yuan , Sheng Yu

Alignment is vital for safely deploying large language models (LLMs). Existing techniques are either reward-based (training a reward model on preference pairs and optimizing with reinforcement learning) or reward-free (directly fine-tuning…

Computation and Language · Computer Science 2026-03-03 Ruoxi Cheng , Haoxuan Ma , Weixin Wang , Ranjie Duan , Jiexi Liu , Xiaoshuang Jia , Simeng Qin , Xiaochun Cao , Yang Liu , Xiaojun Jia

Reward design in reinforcement learning and optimal control is challenging. Preference-based alignment addresses this by enabling agents to learn rewards from ranked trajectory pairs provided by humans. However, existing methods often…

Machine Learning · Computer Science 2025-05-29 Zhixian Xie , Haode Zhang , Yizhe Feng , Wanxin Jin

Reward-model-based fine-tuning is a central paradigm in aligning Large Language Models with human preferences. However, such approaches critically rely on the assumption that proxy reward models accurately reflect intended supervision, a…

Computation and Language · Computer Science 2026-01-21 Zixuan Liu , Siavash H. Khajavi , Guangkai Jiang , Xinru Liu

Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

Computation and Language · Computer Science 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

Reinforcement learning with human feedback for aligning large language models (LLMs) trains a reward model typically using ranking loss with comparison pairs.However, the training procedure suffers from an inherent problem: the uncontrolled…

Computation and Language · Computer Science 2024-09-19 Hang Zhou , Chenglong Wang , Yimin Hu , Tong Xiao , Chunliang Zhang , Jingbo Zhu

Despite notable advancements in Multimodal Large Language Models (MLLMs), most state-of-the-art models have not undergone thorough alignment with human preferences. This gap exists because current alignment research has primarily achieved…

We present CRM (Multi-Agent Collaborative Reward Model), a framework that replaces a single black-box reward model with a coordinated team of specialist evaluators to improve robustness and interpretability in RLHF. Conventional reward…

Artificial Intelligence · Computer Science 2026-01-06 Pei Yang , Ke Zhang , Ji Wang , Xiao Chen , Yuxin Tang , Eric Yang , Lynn Ai , Bill Shi

Recent advances in medical large language models have explored Test-Time Reinforcement Learning (TTRL) to enhance reasoning. However, standard TTRL often relies on majority voting (MV) as a heuristic supervision signal, which can be…

Machine Learning · Computer Science 2026-03-11 Kailong Fan , Anqi Pu , Yichen Wu , Wanhua Li , Yicong Li , Hanspeter Pfister , Huafeng Liu , Xiang Li , Quanzheng Li , Ning Guo

Reinforcement Learning from Human Feedback has become the standard paradigm for language model alignment, where reward models directly determine alignment effectiveness. In this work, we focus on how to evaluate the generalizability of…

Computation and Language · Computer Science 2026-05-05 Yangyang Zhou , Yi-Chen Li

Prior work in multi-objective reinforcement learning typically uses linear reward scalarization with fixed weights, which provably fails to capture non-convex Pareto fronts and thus yields suboptimal results. This limitation becomes…

Machine Learning · Computer Science 2026-04-01 Yining Lu , Zilong Wang , Shiyang Li , Xin Liu , Changlong Yu , Qingyu Yin , Zhan Shi , Zixuan Zhang , Meng Jiang

Reinforcement Learning (RL) offers a powerful framework for optimizing dynamic treatment regimes (DTRs). However, clinical RL is fundamentally bottlenecked by reward engineering: the challenge of defining signals that safely and effectively…

Machine Learning · Computer Science 2026-02-05 Qianyi Xu , Gousia Habib , Feng Wu , Yanrui Du , Zhihui Chen , Swapnil Mishra , Dilruk Perera , Mengling Feng

The deployment of Large Language Models (LLMs) in high-stakes medical settings poses a critical AI alignment challenge, as models can inherit and amplify societal biases, leading to significant disparities. Existing fairness evaluation…

Artificial Intelligence · Computer Science 2025-09-03 Shreyash Adappanavar , Krithi Shailya , Gokul S Krishnan , Sriraam Natarajan , Balaraman Ravindran

Reinforcement learning with verifiable rewards (RLVR) has achieved remarkable success in logical reasoning tasks, yet whether large language model (LLM) alignment requires fundamentally different approaches remains unclear. Given the…

Artificial Intelligence · Computer Science 2026-03-12 Zhaowei Zhang , Xiaohan Liu , Xuekai Zhu , Junchao Huang , Ceyao Zhang , Zhiyuan Feng , Yaodong Yang , Xiaoyuan Yi , Xing Xie

Aligning large language models (LLMs) with human preferences is critical to recent advances in generative artificial intelligence. Reinforcement learning from human feedback (RLHF) is widely applied to achieve this objective. A key step in…

Machine Learning · Statistics 2025-01-03 Pangpang Liu , Chengchun Shi , Will Wei Sun

Medical Question-Answering (QA) encompasses a broad spectrum of tasks, including multiple choice questions (MCQ), open-ended text generation, and complex computational reasoning. Despite this variety, a unified framework for delivering…

Computation and Language · Computer Science 2025-06-23 Xiaotian Zhang , Yuan Wang , Zhaopeng Feng , Ruizhe Chen , Zhijie Zhou , Yan Zhang , Hongxia Xu , Jian Wu , Zuozhu Liu

For task-oriented dialog systems, training a Reinforcement Learning (RL) based Dialog Management module suffers from low sample efficiency and slow convergence speed due to the sparse rewards in RL.To solve this problem, many strategies…

Computation and Language · Computer Science 2021-04-13 Zhengxu Hou , Bang Liu , Ruihui Zhao , Zijing Ou , Yafei Liu , Xi Chen , Yefeng Zheng

Recent advancements in large language models (LLMs) focus on aligning to heterogeneous human expectations and values via multi-objective preference alignment. However, existing methods are dependent on the policy model parameters, which…

Computation and Language · Computer Science 2025-07-22 Kailai Yang , Zhiwei Liu , Qianqian Xie , Jimin Huang , Tianlin Zhang , Sophia Ananiadou