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Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

Pharmaceutical companies continue to seek innovative ways to explore whether a drug under development is likely to be suitable for all or only an identifiable stratum of patients in the target population. The sooner this can be done during…

Methodology · Statistics 2019-12-10 Thomas O. Jemielita , Devan V. Mehrotra

Anatomy evaluation is crucial for understanding the physiological state, diagnosing abnormalities, and guiding medical interventions. Statistical shape modeling (SSM) is vital in this process. By enabling the extraction of quantitative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Krithika Iyer , Mokshagna Sai Teja Karanam , Shireen Elhabian

We propose PRISM, a novel framework designed to overcome the limitations of 2D-based Preference-Based Reinforcement Learning (PBRL) by unifying 3D point cloud modeling and future-aware preference refinement. At its core, PRISM adopts a 3D…

Computation and Language · Computer Science 2025-03-20 Yirong Sun , Yanjun Chen

Deep implicit functions (DIFs), as a kind of 3D shape representation, are becoming more and more popular in the 3D vision community due to their compactness and strong representation power. However, unlike polygon mesh-based templates, it…

Computer Vision and Pattern Recognition · Computer Science 2021-05-14 Zerong Zheng , Tao Yu , Qionghai Dai , Yebin Liu

Statistical shape modeling (SSM) enables population-based quantitative analysis of anatomical shapes, informing clinical diagnosis. Deep learning approaches predict correspondence-based SSM directly from unsegmented 3D images but require…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Jadie Adams , Shireen Elhabian

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

The study of physiology demonstrates that the form (shape)of anatomical structures dictates their functions, and analyzing the form of anatomies plays a crucial role in clinical research. Statistical shape modeling (SSM) is a widely used…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Krithika Iyer , Shireen Y. Elhabian

Clinical investigations of anatomy's structural changes over time could greatly benefit from population-level quantification of shape, or spatiotemporal statistic shape modeling (SSM). Such a tool enables characterizing patient organ cycles…

Machine Learning · Computer Science 2022-09-08 Jadie Adams , Nawazish Khan , Alan Morris , Shireen Elhabian

Statistical shape models (SSMs) are an established way to represent the anatomy of a population with various clinically relevant applications. However, they typically require domain expertise, and labor-intensive landmark annotations to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Lennart Bastian , Alexander Baumann , Emily Hoppe , Vincent Bürgin , Ha Young Kim , Mahdi Saleh , Benjamin Busam , Nassir Navab

Deep implicit functions (DIFs) have emerged as a powerful paradigm for many computer vision tasks such as 3D shape reconstruction, generation, registration, completion, editing, and understanding. However, given a set of 3D shapes with…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Yining Jiao , Carlton Zdanski , Julia Kimbell , Andrew Prince , Cameron Worden , Samuel Kirse , Christopher Rutter , Benjamin Shields , William Dunn , Jisan Mahmud , Marc Niethammer

Accurate 3D shape representation is essential in engineering applications such as design, optimization, and simulation. In practice, engineering workflows require structured, part-based representations, as objects are inherently designed as…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Nicolas Talabot , Olivier Clerc , Arda Cinar Demirtas , Alexis Goujon , Hieu Le , Doruk Oner , Pascal Fua

Matrix functions such as square root, inverse roots, and orthogonalization play a central role in preconditioned gradient methods for neural network training. This has motivated the development of iterative algorithms that avoid explicit…

Machine Learning · Computer Science 2026-01-30 Shenghao Yang , Zhichao Wang , Oleg Balabanov , N. Benjamin Erichson , Michael W. Mahoney

Scene graphs have emerged as accurate descriptive priors for image generation and manipulation tasks, however, their complexity and diversity of the shapes and relations of objects in data make it challenging to incorporate them into the…

Machine Learning · Computer Science 2023-11-07 Pavel Jahoda , Azade Farshad , Yousef Yeganeh , Ehsan Adeli , Nassir Navab

Hybrid neural-physics modeling frameworks through differentiable programming have emerged as powerful tools in scientific machine learning, enabling the integration of known physics with data-driven learning to improve prediction accuracy…

Machine Learning · Computer Science 2025-04-04 Deepak Akhare , Pan Du , Tengfei Luo , Jian-Xun Wang

Causal reasoning provides a language to ask important interventional and counterfactual questions beyond purely statistical association. In medical imaging, for example, we may want to study the causal effect of genetic, environmental, or…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Rajat Rasal , Daniel C. Castro , Nick Pawlowski , Ben Glocker

Large Language Models (LLMs), constrained by their auto-regressive nature, suffer from slow decoding. Speculative decoding methods have emerged as a promising solution to accelerate LLM decoding, attracting attention from both systems and…

Artificial Intelligence · Computer Science 2026-02-03 Xuliang Wang , Yuetao Chen , Maochan Zhen , Fang Liu , Xinzhou Zheng , Xingwu Liu , Hong Xu , Ming Li

Understanding how the brain encodes visual information is a central challenge in neuroscience and machine learning. A promising approach is to reconstruct visual stimuli, essentially images, from functional Magnetic Resonance Imaging (fMRI)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zheng Huang , Enpei Zhang , Weikang Qiu , Yinghao Cai , Carl Yang , Elynn Chen , Xiang Zhang , Rex Ying , Dawei Zhou , Yujun Yan

The research community has witnessed the powerful potential of self-supervised Masked Image Modeling (MIM), which enables the models capable of learning visual representation from unlabeled data. In this paper, to incorporate both the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Wenxuan Wang , Jing Wang , Chen Chen , Jianbo Jiao , Yuanxiu Cai , Shanshan Song , Jiangyun Li

Background: Increasingly, decision-making in healthcare relies on computer models, be it clinical prediction models at point of care or decision-analytic models at the policymaking level. Given the important role models play in both…

Computation · Statistics 2022-02-22 Amin Adibi , Stephanie Harvard , Mohsen Sadatsafavi