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EpiLearn is a Python toolkit developed for modeling, simulating, and analyzing epidemic data. Although there exist several packages that also deal with epidemic modeling, they are often restricted to mechanistic models or traditional…

Machine Learning · Computer Science 2024-09-10 Zewen Liu , Yunxiao Li , Mingyang Wei , Guancheng Wan , Max S. Y. Lau , Wei Jin

Individual-level models, also known as ILMs, are commonly used in epidemics modelling, as they can flexibly incorporate individual-level covariates that influence susceptibility and transmissibility upon infection. However, inference for…

Methodology · Statistics 2025-09-08 Yirao Zhang , Rob Deardon , Lorna Deeth

Nowadays, due to the SARS-CoV-2 pandemic, epidemic modelling is experiencing a constantly growing interest from researchers of heterogeneous fields of study. Indeed, the vast literature on computational epidemiology offers solid grounds for…

Social and Information Networks · Computer Science 2021-06-02 Giulio Rossetti , Letizia Milli , Salvatore Citraro , Virginia Morini

To harness the potential of advanced computing technologies, efficient (real time) analysis of large amounts of data is as essential as are front-line simulations. In order to optimise this process, experts need to be supported by…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-03 Jovana Knežević , Ralf-Peter Mundani , Ernst Rank

We present the R package SimInf which provides an efficient and very flexible framework to conduct data-driven epidemiological modeling in realistic large scale disease spread simulations. The framework integrates infection dynamics in…

Populations and Evolution · Quantitative Biology 2021-08-10 Stefan Widgren , Pavol Bauer , Robin Eriksson , Stefan Engblom

Forecasts of the trajectory of an infectious agent can help guide public health decision making. A traditional approach to forecasting fits a computational model to structured data and generates a predictive distribution. However, human…

Natural microbial communities contain hundreds to thousands of interacting species. For this reason, computational simulations are playing an increasingly important role in microbial ecology. In this manuscript, we present a new…

Populations and Evolution · Quantitative Biology 2020-07-01 Robert Marsland , Wenping Cui , Joshua Goldford , Pankaj Mehta

We report on an ongoing collaboration between epidemiological modellers and visualization researchers by documenting and reflecting upon knowledge constructs -- a series of ideas, approaches and methods taken from existing visualization…

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht

Large Language Models (LLMs) offer new opportunities to accelerate complex interdisciplinary research domains. Epidemic modeling, characterized by its complexity and reliance on network science, dynamical systems, epidemiology, and…

Social and Information Networks · Computer Science 2026-02-26 Mohammad Hossein Samaei , Faryad Darabi Sahneh , Lee W. Cohnstaedt , Caterina Scoglio

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

MiMiC is a framework for modeling large-scale chemical processes that require treatment at multiple resolutions. It does not aim to implement single-handedly all methods required to treat individual subsystems, but instead, it relegates…

Epidemic models are used to analyze the progression or outcome of an epidemic under different control policies like vaccinations, quarantines, lockdowns, use of face-masks, pharmaceutical interventions, etc. When these models accurately…

Quantitative Methods · Quantitative Biology 2022-04-19 Carlos Hernandez-Suarez , Osval Montsinos Lopez , Ramon Solano-Barajas

Reliable epidemiological reasoning requires synthesizing study evidence to infer disease burden, transmission dynamics, and intervention effects at the population level. Existing medical question answering benchmarks primarily emphasize…

Computation and Language · Computer Science 2026-05-27 Mingyang Wei , Dehai Min , Zewen Liu , Yuzhang Xie , Guanchen Wu , Ziyang Zhang , Carl Yang , Max S. Y. Lau , Qi He , Lu Cheng , Wei Jin

Medicine is inherently multimodal and multitask, with diverse data modalities spanning text, imaging. However, most models in medical field are unimodal single tasks and lack good generalizability and explainability. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Lijian Xu , Hao Sun , Ziyu Ni , Hongsheng Li , Shaoting Zhang

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…

Applications · Statistics 2020-12-17 Li Wang , Guannan Wang , Lei Gao , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Zhiling Gu

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical…

Quantitative Methods · Quantitative Biology 2025-09-24 Saurabh Bhardwaj , Gaurav Kumar , Haochen Yang , Shaurya Bhardwaj , Qun Wang , Minjie Shen , Yizhi Wang , Cristabelle Madona De Souza

Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down, vaccination, etc). Hand-designing such strategies is not…

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