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Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating…

Machine Learning · Computer Science 2019-11-28 Saloni Dash , Ritik Dutta , Isabelle Guyon , Adrien Pavao , Andrew Yale , Kristin P. Bennett

We create synthetic biometric databases to study general, fundamental, biometric principles. First, we check the validity of the synthetic database design by comparing it to real data in terms of biometric performance. The real data used…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Lee Friedman , Oleg Komogortsev

Evaluating robustness under temporal distribution shift remains an open challenge. Existing metrics quantify the average decline in performance, but fail to capture how models adapt to evolving data. As a result, temporal degradation is…

Machine Learning · Computer Science 2026-04-09 Lorenzo Iovine , Giacomo Ziffer , Emanuele Della Valle

The rapid growth in data availability has facilitated research and development, yet not all industries have benefited equally due to legal and privacy constraints. The healthcare sector faces significant challenges in utilizing patient data…

Methodology · Statistics 2025-11-18 Katariina Perkonoja , Kari Auranen , Joni Virta

It is generally accepted that relatively more permanent (i.e., more temporally persistent) traits are more valuable for biometric performance than less permanent traits. Although this finding is intuitive, there is no current work…

Cryptography and Security · Computer Science 2020-01-27 Lee Friedman , Hal Stern , Larry R. Price , Oleg V. Komogortsev

Generative models have been found effective for data synthesis due to their ability to capture complex underlying data distributions. The quality of generated data from these models is commonly evaluated by visual inspection for image…

Machine Learning · Computer Science 2022-10-18 Emily Muller , Xu Zheng , Jer Hayes

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

High-dimensional multivariate spatial-temporal data arise frequently in a wide range of applications; however, there are relatively few statistical methods that can simultaneously deal with spatial, temporal and variable-wise dependencies…

Methodology · Statistics 2020-02-05 Elynn Y. Chen , Xin Yun , Rong Chen , Qiwei Yao

We consider the estimation of large covariance and precision matrices from high-dimensional sub-Gaussian or heavier-tailed observations with slowly decaying temporal dependence. The temporal dependence is allowed to be long-range so with…

Statistics Theory · Mathematics 2019-12-23 Hai Shu , Bin Nan

Research on differentially private synthetic tabular data has largely focused on independent and identically distributed rows where each record corresponds to a unique individual. This perspective neglects the temporal complexity in…

Machine Learning · Computer Science 2026-02-04 Lucas Rosenblatt , Peihan Liu , Ryan McKenna , Natalia Ponomareva

Synthetic data adoption in healthcare is driven by privacy concerns, data access limitations, and high annotation costs. We explore synthetic Prolonged Exposure (PE) therapy conversations for PTSD as a scalable alternative for training…

Computation and Language · Computer Science 2025-09-23 Suhas BN , Dominik Mattioli , Saeed Abdullah , Rosa I. Arriaga , Chris W. Wiese , Andrew M. Sherrill

Evaluating generative models for synthetic medical imaging is crucial yet challenging, especially given the high standards of fidelity, anatomical accuracy, and safety required for clinical applications. Standard evaluation of generated…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Yash Deo , Yan Jia , Toni Lassila , William A. P. Smith , Tom Lawton , Siyuan Kang , Alejandro F. Frangi , Ibrahim Habli

Time series (TS) data have consistently been in short supply, yet their demand remains high for training systems in prediction, modeling, classification, and various other applications. Synthesis can serve to expand the sample population,…

Signal Processing · Electrical Eng. & Systems 2024-04-23 Tracey K. M. Lee , H. W. Chan , K. H. Leo , Effie Chew , L. Zhao , Saeid Sanei

We propose a method to generate statistically representative synthetic data from a given dataset. The main goal of our method is for the created data set to mimic the inter--feature correlations present in the original data, while also…

Machine Learning · Computer Science 2025-06-25 Nicklas Jävergård , Rainey Lyons , Adrian Muntean , Jonas Forsman

The use of observational time series data to assess the impact of multi-time point interventions is becoming increasingly common as more health and activity data are collected and digitized via wearables, social media, and electronic health…

Methodology · Statistics 2020-12-01 Roy Adams , Suchi Saria , Michael Rosenblum

Large language models (LLMs) can generate or synthesize clinical text for a wide range of applications, from improving clinical documentation to augmenting clinical text analytics. Yet evaluations typically focus on a narrow aspect -- such…

Computation and Language · Computer Science 2026-05-19 Jinghui Liu , Sarvesh Soni , Anthony Nguyen

Access to individual-level health data is essential for gaining new insights and advancing science. In particular, modern methods based on artificial intelligence rely on the availability of and access to large datasets. In the health…

Enhancing reproducibility and data accessibility is essential to scientific research. However, ensuring data privacy while achieving these goals is challenging, especially in the medical field, where sensitive data are often commonplace.…

Methodology · Statistics 2025-09-24 Marta Cipriani , Lorenzo Di Rocco , Maria Puopolo , Marco Alfò

When modeling longitudinal biomedical data, often dimensionality reduction as well as dynamic modeling in the resulting latent representation is needed. This can be achieved by artificial neural networks for dimension reduction, and…

Machine Learning · Statistics 2023-12-01 Göran Köber , Raffael Kalisch , Lara Puhlmann , Andrea Chmitorz , Anita Schick , Harald Binder

Dependencies among attributes are a common aspect of tabular data. However, whether existing tabular data generation algorithms preserve these dependencies while generating synthetic data is yet to be explored. In addition to the existing…

Machine Learning · Computer Science 2024-09-27 Chaithra Umesh , Kristian Schultz , Manjunath Mahendra , Saparshi Bej , Olaf Wolkenhauer
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