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Tumor spheroids are in vitro three-dimensional, cellular collectives consisting of cancerous cells. Embedding these spheroids in an in vitro fibrous environment, such as a collagen network, to mimic the extracellular matrix (ECM) provides…

Holmboe (1962) postulated that resonant interaction between two or more progressive, linear interfacial waves produces exponentially growing instabilities in idealized (broken-line profiles), homogeneous or density stratified, inviscid…

Fluid Dynamics · Physics 2014-07-02 Anirban Guha , Gregory A. Lawrence

We perform the linear stability analysis for a new model for poromechanical processes with inertia (formulated in mixed form using the solid deformation, fluid pressure, and total pressure) interacting with diffusing and reacting solutes…

This paper concerns multiphase models of tumor growth in interaction with a surrounding tissue, taking into account also the interplay with diffusible nutrients feeding the cells. Models specialize in nonlinear systems of possibly…

Mathematical Physics · Physics 2017-01-20 Andrea Tosin

We show that the interaction of a particle with a directionally solidified interface induces the onset of morphological instability provided that the particle-interface distance falls below a critical value. This instability occurs at…

Materials Science · Physics 2015-06-24 Layachi Hadji

We demonstrate that topological insulators exhibit an intrinsic interfacial instability that amplifies small interface fluctuations, resulting in chaotic behavior during interface growth. This mechanism is fundamentally different from…

Mesoscale and Nanoscale Physics · Physics 2025-12-29 Yutaro Tanaka , Akira Furusaki

Thin liquid films with floating active protein machines are considered. Cyclic mechanical motions within the machines, representing microscopic swimmers, lead to molecular propulsion forces applied to the air-liquid interface. We show that,…

Pattern Formation and Solitons · Physics 2015-05-13 Sergio Alonso , Alexander S. Mikhailov

Uncontrolled growth of tumor cells in confined spaces leads to the accumulation of compressive stress within the tumor. Although the effects of tension within 3D extracellular matrices on tumor growth and invasion are well established, the…

Cell Behavior · Quantitative Biology 2024-04-08 Mrinal Pandey , Young Joon Suh , Minha Kim , Hannah Jane Davis , Jeffrey E Segall , Mingming Wu

Theoretical studies on linear shear instabilities often use simple velocity and density profiles (e.g. constant, piecewise) for obtaining good qualitative and quantitative predictions of the initial disturbances. Furthermore, such simple…

Fluid Dynamics · Physics 2017-09-28 Divyanshu Bhardwaj , Anirban Guha

Understanding the untreated tumor growth kinetics and its intrinsic findings is interesting and intriguing. The aim of this study is to propose an approximate analytical expression that allows to simulate changes in surface charge density…

The application of stress to multiphase solid-liquid systems often results in morphological instabilities. Here we propose a solid-solid phase transformation model for roughening instability in the interface between two porous materials…

Materials Science · Physics 2009-11-13 L. Angheluta , E. Jettestuen , J. Mathiesen , F. Renard , B. Jamtveit

We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

Analysis of PDEs · Mathematics 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

Morphological properties of strained epitaxial films are examined through a mesoscopic approach developed to incorporate both the film crystalline structure and standard continuum theory. Film surface profiles and properties, such as…

Materials Science · Physics 2015-05-18 Zhi-Feng Huang , Ken Elder

Topographical and diffuse interface reconfigurations occur with a change in the solidification rate. In this article we pursue the hypothesis that the interface configuration during solidification is determined by the rate of entropy…

Materials Science · Physics 2017-02-14 Yaw Delali Bensah , J. A. Sekhar

Cell spheroids are a widely used model to investigate cell-cell and cell-matrix interactions in a 3D microenvironment in vitro. Most research on cell spheroids has been focused on their response to various stimuli under static conditions.…

Cell Behavior · Quantitative Biology 2024-04-12 Rosalia Ferraro , Jasmin Di Franco , Sergio Caserta , Stefano Guido

An electron or electron-positron beam streaming through a plasma is notoriously prone to micro-instabilities. For a dilute ultrarelativistic infinite beam, the dominant instability is a mixed mode between longitudinal two-stream and…

We study an instability of thin liquid-vapor layers bounded by rigid parallel walls from both below and above. In this system, the interfacial instability is induced by lateral vapor pressure fluctuation, which is in turn attributed to the…

Fluid Dynamics · Physics 2009-07-30 Kentaro Kanatani

We investigate a novel Marangoni-induced instability that arises exclusively in diffuse fluid interfaces, absent in classical sharp-interface models. Using a validated phase-field Navier-Stokes-Allen-Cahn framework, we linearize the…

Fluid Dynamics · Physics 2026-01-14 Xiangwei Li , Dongdong Wan , Haohao Hao , Christian Diddens , Mengqi Zhang , Huanshu Tan

We consider a system of two coupled parabolic PDEs introduced in [1] to model motility of eukaryotic cells. We study the asymptotic behavior of solutions in the limit of a small parameter related to the width of the interface in phase field…

Analysis of PDEs · Mathematics 2016-02-05 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

The rheological properties of biological tissues are core to processes such as cancer metastasis, wound healing and embryo development. The emergence of tissue and organ structures during morphogenesis requires the precise formation of…

Soft Condensed Matter · Physics 2026-03-10 Aidan J. Nicholas , Suzanne M. Fielding