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Most of the optimal guidance problems can be formulated as nonconvex optimization problems, which can be solved indirectly by relaxation, convexification, or linearization. Although these methods are guaranteed to converge to the global…

Optimization and Control · Mathematics 2024-03-19 Gyubin Park , Jiwoo Choi , Da Hoon Jeong , Jong-Han Kim

Anatomical changes during intensity-modulated proton therapy (IMPT) for head-and-neck cancer (HNC) can shift Bragg peaks, risking tumor underdosing and organ-at-risk overdosing. Treatment replanning is often required to maintain clinically…

Medical Physics · Physics 2025-08-13 Malvern Madondo , Yuan Shao , Yingzi Liu , Jun Zhou , Xiaofeng Yang , Zhen Tian

For industrial product design, it is very important to take into account assembly/disassembly and maintenance operations during the conceptual and prototype design stage. For these operations or other similar operations in a constrained…

Robotics · Computer Science 2010-12-21 Liang Ma , Ruina Ma , Damien Chablat , Fouad Bennis

In the field of parametric partial differential equations, shape optimization represents a challenging problem due to the required computational resources. In this contribution, a data-driven framework involving multiple reduction…

Numerical Analysis · Mathematics 2021-02-23 Nicola Demo , Marco Tezzele , Andrea Mola , Gianluigi Rozza

Parts fabricated by additive manufacturing (AM) are often fabricated first as a near-net shape, a combination of intended nominal geometry and sacrificial support structures, which need to be removed in a subsequent post-processing stage…

Computational Engineering, Finance, and Science · Computer Science 2021-07-19 Amir M. Mirzendehdel , Morad Behandish , Saigopal Nelaturi

We present for the first time a general 6DoF trajectory planning method that can be used in real-time image guided radiation therapy procedures for robotic stabilization of dynamically moving tumor targets. As the radiation beam is always…

Medical Physics · Physics 2018-08-14 Rodney D. Wiersma , Xinmin Liu

CT and MRI are two of the most informative modalities in spinal diagnostics and treatment planning. CT is useful when analysing bony structures, while MRI gives information about the soft tissue. Thus, fusing the information of both…

Neural Radiance Field (NeRF) excels in photo-realistically static scenes, inspiring numerous efforts to facilitate volumetric videos. However, rendering dynamic and long-sequence radiance fields remains challenging due to the significant…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Zihan Zheng , Houqiang Zhong , Qiang Hu , Xiaoyun Zhang , Li Song , Ya Zhang , Yanfeng Wang

Most commercially available fixed-wing aerial vehicles (FWV) can carry only small, lightweight computing hardware such as Jetson TX2 onboard. Solving non-linear trajectory optimization on these computing resources is computationally…

A central problem in the field of radiation therapy (RT) is how to optimally deliver dose to a patient in a way that fully accounts for anatomical position changes over time. As current RT is a static process, where beam intensities are…

Medical Physics · Physics 2019-09-04 Rodney D. Wiersma , Xinmin Liu

The computational cost of traditional Computational Fluid Dynamics-based Aerodynamic Shape Optimization severely restricts design space exploration. This paper introduces TripOptimizer, a fully differentiable deep learning framework for…

Machine Learning · Computer Science 2025-12-04 Parsa Vatani , Mohamed Elrefaie , Farhad Nazarpour , Faez Ahmed

A novel probabilistic approach for the design of mechanical structures with friction interfaces is proposed. The objective function is defined as the probability that a specified performance measure of the forced vibration response is…

Computational Engineering, Finance, and Science · Computer Science 2021-01-01 Malte Krack , Sebastian Tatzko , Lars Panning-von Scheidt , Jörg Wallaschek

In this series of papers, we present a motion planning framework for planning comfortable and customizable motion of nonholonomic mobile robots such as intelligent wheelchairs and autonomous cars. In this first one we present the…

Robotics · Computer Science 2013-05-23 Shilpa Gulati , Chetan Jhurani , Benjamin Kuipers

Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively…

Artificial Intelligence · Computer Science 2023-10-31 Adam White , Margarita Saranti , Artur d'Avila Garcez , Thomas M. H. Hope , Cathy J. Price , Howard Bowman

Multi-modal magnetic resonance imaging (MRI) plays a crucial role in comprehensive disease diagnosis in clinical medicine. However, acquiring certain modalities, such as T2-weighted images (T2WIs), is time-consuming and prone to be with…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Qi Wang , Zhijie Wen , Jun Shi , Qian Wang , Dinggang Shen , Shihui Ying

In this paper we propose tools for high-order mesh optimization and demonstrate their benefits in the context of multi-material Arbitrary Lagrangian-Eulerian (ALE) compressible shock hydrodynamic applications. The mesh optimization process…

Numerical Analysis · Mathematics 2021-04-19 Veselin Dobrev , Patrick Knupp , Tzanio Kolev , Ketan Mittal , Robert Rieben , Vladimir Tomov

A control-theoretic framework for autonomous avatar-guided rehabilitation in virtual reality, based on interpretable, adaptive motor guidance through optimal control, is presented. The framework faces critical challenges in motor…

Systems and Control · Electrical Eng. & Systems 2025-12-11 Francesco De Lellis , Maria Lombardi , Egidio De Benedetto , Pasquale Arpaia , Mario di Bernardo

Efficient observer design and accurate sensor fusion are key in state estimation. This work proposes an optimization-based methodology, termed Trajectory Based Optimization Design (TBOD), allowing the user to easily design observers for…

Robotics · Computer Science 2025-10-02 Federico Oliva , Tom Shaked , Daniele Carnevale , Amir Degani

In recent times, an increasing number of researchers have been devoted to utilizing deep neural networks for end-to-end flight navigation. This approach has gained traction due to its ability to bridge the gap between perception and…

Robotics · Computer Science 2024-10-11 Zhichao Han , Long Xu , Liuao Pei , Fei Gao

Uncertainties such as manufacturing tolerances cause performance variations in complex engineering systems, making robust design optimization (RDO) essential. However, simulation-based RDO faces high computational cost for statistical…

Optimization and Control · Mathematics 2026-02-10 Hyunho Jang , Dongjin Lee
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