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Saliency maps are widely used for visual explanations in deep learning, but a fundamental lack of consensus persists regarding their intended purpose and alignment with diverse user queries. This ambiguity hinders the effective evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Yehonatan Elisha , Seffi Cohen , Oren Barkan , Noam Koenigstein

In this paper, we propose a new method called ProfWeight for transferring information from a pre-trained deep neural network that has a high test accuracy to a simpler interpretable model or a very shallow network of low complexity and a…

Machine Learning · Computer Science 2018-11-20 Amit Dhurandhar , Karthikeyan Shanmugam , Ronny Luss , Peder Olsen

Input gradients have a pivotal role in a variety of applications, including adversarial attack algorithms for evaluating model robustness, explainable AI techniques for generating Saliency Maps, and counterfactual explanations.However,…

Artificial Intelligence · Computer Science 2024-02-05 Mathieu Serrurier , Franck Mamalet , Thomas Fel , Louis Béthune , Thibaut Boissin

While observational data are routinely used to estimate causal effects of biomedical treatments, doing so requires special methods to adjust for observed confounding. These methods invariably rely on untestable statistical and causal…

Methodology · Statistics 2026-03-02 Arman Oganisian

Existing state-of-the-art saliency detection methods heavily rely on CNN-based architectures. Alternatively, we rethink this task from a convolution-free sequence-to-sequence perspective and predict saliency by modeling long-range…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Nian Liu , Ni Zhang , Kaiyuan Wan , Ling Shao , Junwei Han

Predicting the impact of genomic and drug perturbations in cellular function is crucial for understanding gene functions and drug effects, ultimately leading to improved therapies. To this end, Causal Representation Learning (CRL)…

Motivation : Molecular signatures for diagnosis or prognosis estimated from large-scale gene expression data often lack robustness and stability, rendering their biological interpretation challenging. Increasing the signature's…

Machine Learning · Statistics 2010-01-19 Anne-Claire Haury , Laurent Jacob , Jean-Philippe Vert

To foster trust in machine learning models, explanations must be faithful and stable for consistent insights. Existing relevant works rely on the $\ell_p$ distance for stability assessment, which diverges from human perception. Besides,…

Machine Learning · Computer Science 2024-12-30 Chao Chen , Chenghua Guo , Rufeng Chen , Guixiang Ma , Ming Zeng , Xiangwen Liao , Xi Zhang , Sihong Xie

We develop a linear response framework for interpretability that treats a neural network as a Bayesian statistical mechanical system. A small perturbation of the data distribution, for example shifting the Pile toward GitHub or legal text,…

Machine Learning · Computer Science 2026-03-10 Garrett Baker , George Wang , Jesse Hoogland , Daniel Murfet

Recurrent neural networks (RNNs) are temporal networks and cumulative in nature that have shown promising results in various natural language processing tasks. Despite their success, it still remains a challenge to understand their hidden…

Computation and Language · Computer Science 2018-08-07 Pankaj Gupta , Hinrich Schütze

Current deep learning-based solutions for image analysis tasks are commonly incapable of handling problems to which multiple different plausible solutions exist. In response, posterior-based methods such as conditional Diffusion Models and…

A common approach to quantifying neural text classifier interpretability is to calculate faithfulness metrics based on iteratively masking salient input tokens and measuring changes in the model prediction. We propose that this property is…

Computation and Language · Computer Science 2024-06-04 Evan Crothers , Herna Viktor , Nathalie Japkowicz

Sensitivity analysis informs causal inference by assessing the sensitivity of conclusions to departures from assumptions. The consistency assumption states that there are no hidden versions of treatment and that the outcome arising…

Methodology · Statistics 2025-12-29 Brian Knaeble , Qinyun Lin , Erich Kummerfeld , Kenneth A. Frank

Accurately measuring protein-RNA binding affinity is crucial in many biological processes and drug design. Previous computational methods for protein-RNA binding affinity prediction rely on either sequence or structure features, unable to…

Biomolecules · Quantitative Biology 2025-01-06 Rong Han , Xiaohong Liu , Tong Pan , Jing Xu , Xiaoyu Wang , Wuyang Lan , Zhenyu Li , Zixuan Wang , Jiangning Song , Guangyu Wang , Ting Chen

In single-cell perturbation prediction, a central task is to forecast the effects of perturbing a gene unseen in the training data. The efficacy of such predictions depends on two factors: (1) the similarity of the target gene to those…

Machine Learning · Computer Science 2025-10-10 Jiabei Cheng , Changxi Chi , Jingbo Zhou , Hongyi Xin , Jun Xia

Saliency Map, the gradient of the score function with respect to the input, is the most basic technique for interpreting deep neural network decisions. However, saliency maps are often visually noisy. Although several hypotheses were…

Machine Learning · Computer Science 2019-09-17 Beomsu Kim , Junghoon Seo , SeungHyun Jeon , Jamyoung Koo , Jeongyeol Choe , Taegyun Jeon

Saliency methods compute heat maps that highlight portions of an input that were most {\em important} for the label assigned to it by a deep net. Evaluations of saliency methods convert this heat map into a new {\em masked input} by…

Machine Learning · Statistics 2022-11-08 Arushi Gupta , Nikunj Saunshi , Dingli Yu , Kaifeng Lyu , Sanjeev Arora

Machine learning systems in fraud detection, credit scoring, and clinical risk assessment operate under delayed ground truth: outcome labels arrive days to months after the decision they evaluate. During this blind period, governance…

Computers and Society · Computer Science 2026-04-20 Oleg Solozobov

Since 2014 transfer learning has become the key driver for the improvement of spatial saliency prediction; however, with stagnant progress in the last 3-5 years. We conduct a large-scale transfer learning study which tests different…

Machine Learning · Computer Science 2021-09-21 Akis Linardos , Matthias Kümmerer , Ori Press , Matthias Bethge

Visual-prompt-guided edit transfer aims to learn image transformations directly from example pairs, offering more precise and controllable editing than purely text-driven approaches. However, existing diffusion transformer-based methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Lan Chen , Qi Mao , Yiren Song , Yuchao Gu , Siwei Ma