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Physics-Informed Neural Networks (PINNs) are machine learning tools that approximate the solution of general partial differential equations (PDEs) by adding them in some form as terms of the loss/cost function of a Neural Network. Most…

Numerical Analysis · Mathematics 2022-08-29 Antonio Tadeu Azevedo Gomes , Larissa Miguez da Silva , Frederic Valentin

Physics-informed neural networks (PINNs) have been proposed to solve two main classes of problems: data-driven solutions and data-driven discovery of partial differential equations. This task becomes prohibitive when such data is highly…

Machine Learning · Computer Science 2022-10-20 Wei Peng , Wen Yao , Weien Zhou , Xiaoya Zhang , Weijie Yao

Standard Physics-Informed Neural Networks (PINNs) often face challenges when modeling parameterized dynamical systems with sharp regime transitions, such as bifurcations. In these scenarios, the continuous mapping from parameters to…

Machine Learning · Computer Science 2026-03-06 Enzo Nicolas Spotorno , Josafat Ribeiro Leal , Antonio Augusto Frohlich

Physics-informed neural networks (PINNs) incorporate physical laws into their training to efficiently solve partial differential equations (PDEs) with minimal data. However, PINNs fail to guarantee adherence to conservation laws, which are…

Machine Learning · Computer Science 2024-10-24 Anthony Baez , Wang Zhang , Ziwen Ma , Subhro Das , Lam M. Nguyen , Luca Daniel

We introduce PINGS (Physics-Informed Neural Network for Fast Generative Sampling), a framework that amortizes diffusion sampling by training a physics-informed network to approximate reverse-time probability-flow dynamics, reducing sampling…

Physics-informed neural networks (PINNs) represent a new paradigm for solving partial differential equations (PDEs) by integrating physical laws into the learning process of neural networks. However, ensuring that such frameworks fully…

Machine Learning · Computer Science 2025-12-12 Nanxi Chen , Sifan Wang , Rujin Ma , Airong Chen , Chuanjie Cui

Physics-informed neural networks (PINNs) have emerged as a promising numerical method based on deep learning for modeling boundary value problems, showcasing promising results in various fields. In this work, we use PINNs to discretize…

Computational Physics · Physics 2024-06-10 Michel Nohra , Steven Dufour

Physics-informed neural networks (PINNs) have emerged as a flexible framework for solving partial differential equations, but their performance on interface problems remains challenging because continuity and flux conditions are typically…

Numerical Analysis · Mathematics 2026-05-19 Seung Whan Chung , Stephen T. Castonguay , Sumanta Roy , Michael S. Penwarden , Yucheng Fu , Pratanu Roy

In this study, we present and validate the predictive capability of the Physics-Informed Neural Networks (PINNs) methodology for solving a variety of engineering and biological dynamical systems governed by ordinary differential equations…

Machine Learning · Computer Science 2025-11-19 Tyrus Whitman , Andrew Particka , Christopher Diers , Ian Griffin , Charuka Wickramasinghe , Pradeep Ranaweera

Recently developed physics-informed neural network (PINN) has achieved success in many science and engineering disciplines by encoding physics laws into the loss functions of the neural network, such that the network not only conforms to…

Numerical Analysis · Mathematics 2021-11-17 Weiqi Ji , Weilun Qiu , Zhiyu Shi , Shaowu Pan , Sili Deng

Time-fractional differential equations offer a robust framework for capturing intricate phenomena characterized by memory effects, particularly in fields like biotransport and rheology. However, solving inverse problems involving fractional…

Neural and Evolutionary Computing · Computer Science 2024-07-16 Sukirt Thakur , Harsa Mitra , Arezoo M. Ardekani

We propose a randomized physics-informed neural network (PINN) or rPINN method for uncertainty quantification in inverse partial differential equation (PDE) problems with noisy data. This method is used to quantify uncertainty in the…

Machine Learning · Computer Science 2024-07-08 Yifei Zong , David Barajas-Solano , Alexandre M. Tartakovsky

Physics-Informed Neural Networks (PINNs) have emerged as a powerful framework for solving partial differential equations (PDEs) by embedding physical laws into neural network training. However, traditional PINN models are typically designed…

Machine Learning · Computer Science 2025-05-05 Keon Vin Park

The recent surge of interest in physics-informed neural network (PINN) methods has led to a wave of studies that attest to their potential for solving partial differential equations (PDEs) and predicting the dynamics of physical systems.…

Computational Engineering, Finance, and Science · Computer Science 2023-06-02 Pi-Yueh Chuang , Lorena A. Barba

Mathematical models in neural networks are powerful tools for solving complex differential equations and optimizing their parameters; that is, solving the forward and inverse problems, respectively. A forward problem predicts the output of…

Machine Learning · Computer Science 2025-07-29 Aarush Gupta , Kendric Hsu , Syna Mathod

Physics-informed neural networks (PINNs) have shown to be an effective tool for solving forward and inverse problems of partial differential equations (PDEs). PINNs embed the PDEs into the loss of the neural network, and this PDE loss is…

Computational Physics · Physics 2023-07-19 Chenxi Wu , Min Zhu , Qinyang Tan , Yadhu Kartha , Lu Lu

The utilization of Deep Neural Networks (DNNs) in physical science and engineering applications has gained traction due to their capacity to learn intricate functions. While large datasets are crucial for training DNN models in fields like…

Machine Learning · Computer Science 2025-08-05 Vamsi Sai Krishna Malineni , Suresh Rajendran

Neural networks, while powerful, often lack interpretability. Physics-Informed Neural Networks (PINNs) address this limitation by incorporating physics laws into the loss function, making them applicable to solving Ordinary Differential…

Machine Learning · Computer Science 2024-04-17 Jonas Ekeland Kittelsen , Eric Aislan Antonelo , Eduardo Camponogara , Lars Struen Imsland

Physics-informed Neural Networks (PINNs) have recently emerged as a principled way to include prior physical knowledge in form of partial differential equations (PDEs) into neural networks. Although PINNs are generally viewed as mesh-free,…

Machine Learning · Computer Science 2022-10-04 Fabricio Arend Torres , Marcello Massimo Negri , Monika Nagy-Huber , Maxim Samarin , Volker Roth

Pharmacometric models are pivotal across drug discovery and development, playing a decisive role in determining the progression of candidate molecules. However, the derivation of mathematical equations governing the system is a…

Machine Learning · Computer Science 2024-05-02 Imran Nasim , Adam Nasim