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Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Jinquan Guan , Qi Chen , Lizhou Liang , Yuhang Liu , Vu Minh Hieu Phan , Minh-Son To , Jian Chen , Yutong Xie

Vision-Language Models (VLMs) have shown significant potential in surgical scene analysis, yet existing models are limited by frame-level datasets and lack high-quality video data with procedural surgical knowledge. To address these…

Other Quantitative Biology · Quantitative Biology 2026-01-21 Yaoqian Li , Xikai Yang , Dunyuan Xu , Yang Yu , Litao Zhao , Xiaowei Hu , Jinpeng Li , Pheng-Ann Heng

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to…

Artificial Intelligence · Computer Science 2024-03-28 Nisha Pillai , Athish Ram Das , Moses Ayoola , Ganga Gireesan , Bindu Nanduri , Mahalingam Ramkumar

Interpretability is significant in computational pathology, leading to the development of multimodal information integration from histopathological image and corresponding text data.However, existing multimodal methods have limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Kangcheng Zhou , Jun Jiang , Qing Zhang , Shuang Zheng , Qingli Li , Shugong Xu

Recent advances in foundational Vision Language Models (VLMs) have reshaped the evaluation paradigm in computer vision tasks. These foundational models, especially CLIP, have accelerated research in open-vocabulary computer vision tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 M. Arda Aydın , Efe Mert Çırpar , Elvin Abdinli , Gozde Unal , Yusuf H. Sahin

Alignment techniques have become central to ensuring that Large Language Models (LLMs) generate outputs consistent with human values. However, existing alignment paradigms often model an averaged or monolithic preference, failing to account…

Computation and Language · Computer Science 2025-06-03 Anudeex Shetty , Amin Beheshti , Mark Dras , Usman Naseem

Large vision-language models (LVLMs) have demonstrated exceptional capabilities in understanding visual information with human languages but also exhibit an imbalance in multilingual capabilities. In this work, we delve into the…

Computation and Language · Computer Science 2025-08-27 Yuchun Fan , Yilin Wang , Yongyu Mu , Lei Huang , Bei Li , Xiaocheng Feng , Tong Xiao , Jingbo Zhu

Liver cancer has a high incidence rate, but primary healthcare settings often lack experienced doctors. Advances in large models and AI technologies offer potential assistance. This work aims to address limitations in liver cancer diagnosis…

Medical Physics · Physics 2024-06-27 Xuzhou Wu , Guangxin Li , Xing Wang , Zeyu Xu , Yingni Wang , Jianming Xian , Xueyu Wang , Gong Li , Kehong Yuan

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

The surgical intervention is crucial to patient healthcare, and many studies have developed advanced algorithms to provide understanding and decision-making assistance for surgeons. Despite great progress, these algorithms are developed for…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Zhen Chen , Xingjian Luo , Jinlin Wu , Danny T. M. Chan , Zhen Lei , Jinqiao Wang , Sebastien Ourselin , Hongbin Liu

Multimodal large language models (MLLMs) that integrate visual and textual reasoning leverage chain-of-thought (CoT) prompting to tackle complex visual tasks, yet continue to exhibit visual hallucinations and an over-reliance on textual…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Jing Bi , Guangyu Sun , Ali Vosoughi , Chen Chen , Chenliang Xu

Recent progress in medical vision-language models (VLMs) has achieved strong performance on image-level text-centric tasks such as report generation and visual question answering (VQA). However, achieving fine-grained visual grounding and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Yang Xing , Jiong Wu , Savas Ozdemir , Ying Zhang , Yang Yang , Wei Shao , Kuang Gong

Multimodal learning has shown promise in medical imaging, combining complementary modalities like images and text. Vision-language models (VLMs) capture rich diagnostic cues but often require large paired datasets and prompt- or text-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Banafsheh Karimian , Giulia Avanzato , Soufian Belharbi , Alexis Guichemerre , Luke McCaffrey , Mohammadhadi Shateri , Eric Granger

Large language models (LLMs) hold great promise for assisting clinical interviews due to their fluent interactive capabilities and extensive medical knowledge. However, the lack of high-quality interview dialogue data and widely accepted…

Computation and Language · Computer Science 2025-04-15 Jing Chen , Zhihua Wei , Wei Zhang , Yingying Hu , Qiong Zhang

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

Understanding 3D medical image volumes is critical in the medical field, yet existing 3D medical convolution and transformer-based self-supervised learning (SSL) methods often lack deep semantic comprehension. Recent advancements in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Qiuhui Chen , Xuancheng Yao , Huping Ye , Yi Hong

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Alejandro Lozano , Jeffrey Nirschl , James Burgess , Sanket Rajan Gupte , Yuhui Zhang , Alyssa Unell , Serena Yeung-Levy

In this study, we investigate the potential of Large Language Models to complement biomedical knowledge graphs in the training of semantic models for the biomedical and clinical domains. Drawing on the wealth of the UMLS knowledge graph and…

Computation and Language · Computer Science 2023-11-28 François Remy , Kris Demuynck , Thomas Demeester

Medical Large Vision-Language Models (Med-LVLMs) have shown promising results in clinical applications, but often suffer from hallucinated outputs due to misaligned visual understanding. In this work, we identify two fundamental limitations…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Aofei Chang , Ting Wang , Fenglong Ma