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Background: Although Alzheimer's disease (AD) is a central nervous system disease and type 2 diabetes mellitus (T2DM) is a metabolic disorder, an increasing number of genetic epidemiological studies show clear link between AD and T2DM. The…

Molecular Networks · Quantitative Biology 2019-01-18 Zixin Hu , Rong Jiao , Jiucun Wang , Panpan Wang , Yun Zhu , Jinying Zhao , Phil De Jager , David A Bennett , Li Jin , Momiao Xiong

This paper presents the results of a study on the perception of illness and adaptation parameters in patients with type 2 diabetes. The study involved 173 patients diagnosed with "Type 2 Diabetes" (ICD-11 code 5 A 11). The average age of…

Quantitative Methods · Quantitative Biology 2023-12-19 A. Y. Timashkov , I. N. Abrosimov , V. M. Yaltonsky

Disease progression modeling aims to characterize and predict how a patient's disease complications worsen over time based on longitudinal electronic health records (EHRs). For diseases such as type 2 diabetes, accurate progression modeling…

Artificial Intelligence · Computer Science 2026-03-31 Tingsong Xiao , Yao An Lee , Zelin Xu , Yupu Zhang , Zibo Liu , Yu Huang , Jiang Bian , Jingchuan Guo , Zhe Jiang

Disease-gene association through Genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations.…

Quantitative Methods · Quantitative Biology 2020-12-21 Sezin Kircali Ata , Min Wu , Yuan Fang , Le Ou-Yang , Chee Keong Kwoh , Xiao-Li Li

Type 1 diabetes is a serious disease in which individuals are unable to regulate their blood glucose levels, leading to various medical complications. Artificial pancreas (AP) systems have been developed as a solution for type 1 diabetic…

Signal Processing · Electrical Eng. & Systems 2023-05-18 Ke Ma , Hongkai Chen , Shan Lin

Research in diabetes, especially when it comes to building data-driven models to forecast future glucose values, is hindered by the sensitive nature of the data. Because researchers do not share the same data between studies, progress is…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Diabetes-related retinal conditions can be detected by examining the posterior of the eye. By contrast, examining the anterior of the eye can reveal conditions affecting the front of the eye, such as changes to the eyelids, cornea, or…

Single-cell RNA sequencing (scRNA-seq) has revolutionized biological discovery, providing an unbiased picture of cellular heterogeneity in tissues. While scRNA-seq has been used extensively to provide insight into both healthy systems and…

Genomics · Quantitative Biology 2020-03-16 Neal G. Ravindra , Arijit Sehanobish , Jenna L. Pappalardo , David A. Hafler , David van Dijk

Body Dysmorphic Disorder (BDD) is a highly prevalent and frequently underdiagnosed condition characterized by persistent, intrusive preoccupations with perceived defects in physical appearance. In this extended analysis, we employ multiple…

Machine Learning · Computer Science 2025-03-17 Omar Costilla-Reyes , Morgan Talbot

Complex survey designs are commonly employed in many medical cohorts. In such scenarios, developing case-specific predictive risk score models that reflect the unique characteristics of the study design is essential for minimizing selective…

Methodology · Statistics 2025-03-27 Marcos Matabuena , Juan C. Vidal , Rahul Ghosal , Jukka-Pekka Onnela

In the UK, approximately 400,000 people with type 1 diabetes (T1D) rely on insulin delivery due to insufficient pancreatic insulin production. Managing blood glucose (BG) levels is crucial, with continuous glucose monitoring (CGM) playing a…

Machine Learning · Computer Science 2023-12-21 Chengzhe Piao , Ken Li

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

Automated learning of patients demographics can be seen as multi-label problem where a patient model is based on different race and gender groups. The resulting model can be further integrated into Privacy-Preserving Data Mining, where it…

Machine Learning · Computer Science 2015-03-27 Naveen Kumar Parachur Cotha , Marina Sokolova

Type 2 diabetes (T2DM), one of the most prevalent chronic diseases, affects the glucose metabolism of the human body, which decreases the quantity of life and brings a heavy burden on social medical care. Patients with T2DM are more likely…

Quantitative Methods · Quantitative Biology 2020-07-01 Wei Wang , Gangqiang Hu , Bo Yuan , Shandong Ye , Chao Chen , YaYun Cui , Xi Zhang , Liting Qian

With the prevalence of Diabetes, the Diabetes Mellitus Retinopathy (DR) is becoming a major health problem across the world. The long-term medical complications arising due to DR have a significant impact on the patient as well as the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Shreyas Rajesh Labhsetwar , Raj Sunil Salvi , Piyush Arvind Kolte , Veerasai Subramaniam venkatesh , Alistair Michael Baretto

Postprandial hyperglycemia, marked by the blood glucose level exceeding the normal range after consuming a meal, is a critical indicator of progression toward type 2 diabetes in people with prediabetes and in healthy individuals. A key…

Problem Definition. Increasing costs of healthcare highlight the importance of effective disease prevention. However, decision models for allocating preventive care are lacking. Methodology/Results. In this paper, we develop a data-driven…

Machine Learning · Computer Science 2023-08-15 Mathias Kraus , Stefan Feuerriegel , Maytal Saar-Tsechansky

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

Cardiovascular Disease (CVD) is an important cause of disability and death among individuals with Diabetes Mellitus (DM). International clinical guidelines for the management of Type 2 DM (T2DM) are founded on primary and secondary…

Diabetic retinopathy (DR) is one of the leading causes of blindness in the working-age population of developed countries, caused by a side effect of diabetes that reduces the blood supply to the retina. Deep neural networks have been widely…

Computer Vision and Pattern Recognition · Computer Science 2022-08-05 Jose Miguel Arrieta Ramos , Oscar Perdómo , Fabio A. González
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