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Raman spectroscopy is widely used across scientific domains to characterize the chemical composition of samples in a non-destructive, label-free manner. Many applications entail the unmixing of signals from mixtures of molecular species to…

Molecular machine learning has gained popularity with the advancements of geometric deep learning. In parallel, retrieval-augmented generation has become a principled approach commonly used with language models. However, the optimal…

Machine Learning · Computer Science 2025-07-04 Runzhong Wang , Rui-Xi Wang , Mrunali Manjrekar , Connor W. Coley

Machine learning potentials (MLPs) achieve near first-principles accuracy but often fail for atomic environments outside the training distribution. Active learning can mitigate this limitation; however, its application to large-scale…

Computational Physics · Physics 2026-04-16 Junjie Wang , Shuning Pan , Haoting Zhang , Qiuhan Jia , Chi Ding , Zheyong Fan , Jian Sun

Kernel methods provide a theoretically grounded framework for non-linear and non-parametric learning, with strong analytic foundations and statistical guarantees. Yet, their scalability has long been limited by prohibitive time and memory…

Machine Learning · Computer Science 2025-10-01 Maedeh Zarvandi , Michael Timothy , Theresa Wasserer , Debarghya Ghoshdastidar

Infrared and Raman spectroscopy are widely used for the characterization of gases, liquids, and solids, as the spectra contain a wealth of information concerning in particular the dynamics of these systems. Atomic scale simulations can be…

Mesoscale and Nanoscale Physics · Physics 2024-08-15 Nan Xu , Petter Rosander , Christian Schäfer , Eric Lindgren , Nicklas Österbacka , Mandi Fang , Wei Chen , Yi He , Zheyong Fan , Paul Erhart

In medical information extraction, medical Named Entity Recognition (NER) is indispensable, playing a crucial role in developing medical knowledge graphs, enhancing medical question-answering systems, and analyzing electronic medical…

Computation and Language · Computer Science 2024-03-26 Xiaojing Du , Hanjie Zhao , Danyan Xing , Yuxiang Jia , Hongying Zan

Nonsense-mediated mRNA decay (NMD) is a critical post-transcriptional surveillance mechanism that degrades transcripts with premature termination codons, safeguarding transcriptome integrity and shaping disease phenotypes. However,…

Genomics · Quantitative Biology 2025-02-21 Ali Saadat , Jacques Fellay

Mass spectrometry imaging (MSI) enables label-free visualization of molecular distributions across tissue samples but generates large and complex datasets that require effective peak picking to reduce data size while preserving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Philipp Weigand , Nikolas Ebert , Shad A. Mohammed , Denis Abu Sammour , Carsten Hopf , Oliver Wasenmüller

Characterization of the molecular properties of surfaces under ambient or chemically reactive conditions is a fundamental scientific challenge. Moreover, many traditional analytical techniques used for probing surfaces often lack dynamic or…

Neurophysiological decoding, fundamental to advancing brain-computer interface (BCI) technologies, has significantly benefited from recent advances in deep learning. However, existing decoding approaches largely remain constrained to…

Signal Processing · Electrical Eng. & Systems 2025-08-07 Di Wu , Yifei Jia , Siyuan Li , Shiqi Zhao , Jie Yang , Mohamad Sawan

The density matrix renormalization group (DMRG) algorithm is a cornerstone computational method for studying quantum many-body systems, renowned for its accuracy and adaptability. Despite DMRG's broad applicability across fields such as…

Computational Physics · Physics 2026-03-24 Per Sehlstedt , Jan Brandejs , Paolo Bientinesi , Lars Karlsson

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

Neuromorphic computing shows promise for advancing computing efficiency and capabilities of AI applications using brain-inspired principles. However, the neuromorphic research field currently lacks standardized benchmarks, making it…

Artificial Intelligence · Computer Science 2025-01-16 Jason Yik , Korneel Van den Berghe , Douwe den Blanken , Younes Bouhadjar , Maxime Fabre , Paul Hueber , Weijie Ke , Mina A Khoei , Denis Kleyko , Noah Pacik-Nelson , Alessandro Pierro , Philipp Stratmann , Pao-Sheng Vincent Sun , Guangzhi Tang , Shenqi Wang , Biyan Zhou , Soikat Hasan Ahmed , George Vathakkattil Joseph , Benedetto Leto , Aurora Micheli , Anurag Kumar Mishra , Gregor Lenz , Tao Sun , Zergham Ahmed , Mahmoud Akl , Brian Anderson , Andreas G. Andreou , Chiara Bartolozzi , Arindam Basu , Petrut Bogdan , Sander Bohte , Sonia Buckley , Gert Cauwenberghs , Elisabetta Chicca , Federico Corradi , Guido de Croon , Andreea Danielescu , Anurag Daram , Mike Davies , Yigit Demirag , Jason Eshraghian , Tobias Fischer , Jeremy Forest , Vittorio Fra , Steve Furber , P. Michael Furlong , William Gilpin , Aditya Gilra , Hector A. Gonzalez , Giacomo Indiveri , Siddharth Joshi , Vedant Karia , Lyes Khacef , James C. Knight , Laura Kriener , Rajkumar Kubendran , Dhireesha Kudithipudi , Shih-Chii Liu , Yao-Hong Liu , Haoyuan Ma , Rajit Manohar , Josep Maria Margarit-Taulé , Christian Mayr , Konstantinos Michmizos , Dylan R. Muir , Emre Neftci , Thomas Nowotny , Fabrizio Ottati , Ayca Ozcelikkale , Priyadarshini Panda , Jongkil Park , Melika Payvand , Christian Pehle , Mihai A. Petrovici , Christoph Posch , Alpha Renner , Yulia Sandamirskaya , Clemens JS Schaefer , André van Schaik , Johannes Schemmel , Samuel Schmidgall , Catherine Schuman , Jae-sun Seo , Sadique Sheik , Sumit Bam Shrestha , Manolis Sifalakis , Amos Sironi , Kenneth Stewart , Matthew Stewart , Terrence C. Stewart , Jonathan Timcheck , Nergis Tömen , Gianvito Urgese , Marian Verhelst , Craig M. Vineyard , Bernhard Vogginger , Amirreza Yousefzadeh , Fatima Tuz Zohora , Charlotte Frenkel , Vijay Janapa Reddi

Humans interpret and perceive the world by integrating sensory information from multiple modalities, such as vision and hearing. Spiking Neural Networks (SNNs), as brain-inspired computational models, exhibit unique advantages in emulating…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Xiang He , Dongcheng Zhao , Yiting Dong , Guobin Shen , Xin Yang , Yi Zeng

Carbohydrates, vital components of biological systems, are well-known for their structural diversity. Nuclear Magnetic Resonance (NMR) spectroscopy plays a crucial role in understanding their intricate molecular arrangements and is…

Machine Learning · Computer Science 2023-11-22 Maria Bånkestad , Keven M. Dorst , Göran Widmalm , Jerk Rönnols

In drug discovery, molecular dynamics (MD) simulation for protein-ligand binding provides a powerful tool for predicting binding affinities, estimating transport properties, and exploring pocket sites. There has been a long history of…

We introduce the Normalized Matching Transformer (NMT), a deep learning approach for efficient and accurate sparse semantic keypoint matching between image pairs. NMT consists of a strong visual backbone, geometric feature refinement via…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Abtin Pourhadi , Paul Swoboda

The interpretability of machine learning, particularly for deep neural networks, is crucial for decision making in real-world applications. One approach is replacing the un-interpretable machine learning model with a surrogate model, which…

Machine Learning · Statistics 2020-07-22 Keiichi Kisamori , Keisuke Yamazaki , Yuto Komori , Hiroshi Tokieda

Modeling the relationship between chemical structure and molecular activity is a key goal in drug development. Many benchmark tasks have been proposed for molecular property prediction, but these tasks are generally aimed at specific,…

Quantitative Methods · Quantitative Biology 2020-10-05 Samuel G. Finlayson , Matthew B. A. McDermott , Alex V. Pickering , Scott L. Lipnick , Isaac S. Kohane

Accurate clinical prognosis requires synthesizing structured Electronic Health Records (EHRs) with real-time physiological signals like the Electrocardiogram (ECG). Large Language Models (LLMs) offer a powerful reasoning engine for this…

Machine Learning · Computer Science 2026-01-27 Jialu Tang , Tong Xia , Yuan Lu , Aaqib Saeed