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Foundation models for image segmentation have shown strong generalization in natural images, yet their applicability to 3D medical imaging remains limited. In this work, we study the zero-shot use of Segment Anything Model 2 (SAM2) for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Miquel Lopez Escoriza , Pau Amargant Alvarez

Segmentation in medical imaging is a critical component for the diagnosis, monitoring, and treatment of various diseases and medical conditions. Presently, the medical segmentation landscape is dominated by numerous specialized deep…

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Medical image segmentation has achieved remarkable success through the continuous advancement of UNet-based and Transformer-based foundation backbones. However, clinical diagnosis in the real world often requires integrating domain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Siyuan Dai , Kai Ye , Guodong Liu , Haoteng Tang , Liang Zhan

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Biomedical image segmentation plays a vital role in diagnosis of diseases across various organs. Deep learning-based object detection methods are commonly used for such segmentation. There exists an extensive research in this topic.…

Image and Video Processing · Electrical Eng. & Systems 2024-08-30 Fazli Wahid , Yingliang Ma , Dawar Khan , Muhammad Aamir , Syed U. K. Bukhari

The Segment Anything Model (SAM) and similar models build a family of promptable foundation models (FMs) for image and video segmentation. The object of interest is identified using prompts, such as bounding boxes or points. With these FMs…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Caroline Magg , Hoel Kervadec , Clara I. Sánchez

Large-scale vision-language models (VLMs), trained on extensive datasets of image-text pairs, exhibit strong multimodal understanding capabilities by implicitly learning associations between textual descriptions and image regions. This…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Mir Rayat Imtiaz Hossain , Mennatullah Siam , Leonid Sigal , James J. Little

The Segment Anything Model (SAM) exhibits remarkable versatility and zero-shot learning abilities, owing largely to its extensive training data (SA-1B). Recognizing SAM's dependency on manual guidance given its category-agnostic nature, we…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Xiyu Qi , Yifan Wu , Yongqiang Mao , Wenhui Zhang , Yidan Zhang

It is well known that machine learning models require a high amount of annotated data to obtain optimal performance. Labelling Computed Tomography (CT) data can be a particularly challenging task due to its volumetric nature and often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Franko Hrzic , Mohammadreza Movahhedi , Ophelie Lavoie-Gagne , Ata Kiapour

Methods for object detection and segmentation often require abundant instance-level annotations for training, which are time-consuming and expensive to collect. To address this, the task of zero-shot object detection (or segmentation) aims…

Computer Vision and Pattern Recognition · Computer Science 2023-02-16 Siddhesh Khandelwal , Anirudth Nambirajan , Behjat Siddiquie , Jayan Eledath , Leonid Sigal

While foundation models in radiology are expected to be applied to various clinical tasks, computational cost constraints remain a major challenge when training on 3D-CT volumetric data. In this study, we propose TotalFM, a radiological…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Kohei Yamamoto , Tomohiro Kikuchi

We introduce SAM3D, a new approach to semi-automatic zero-shot segmentation of 3D images building on the existing Segment Anything Model. We achieve fast and accurate segmentations in 3D images with a four-step strategy involving: user…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Trevor J. Chan , Aarush Sahni , Yijin Fang , Jie Li , Alisha Luthra , Alison Pouch , Chamith S. Rajapakse

Most deep learning models in medical imaging are trained on adult data with unclear performance on pediatric images. In this work, we aim to address this challenge in the context of automated anatomy segmentation in whole-body Computed…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Chih-Ying Liu , Jeya Maria Jose Valanarasu , Camila Gonzalez , Curtis Langlotz , Andrew Ng , Sergios Gatidis

Vision-language models (VLMs) trained on internet-scale data achieve remarkable zero-shot detection performance on common objects like car, truck, and pedestrian. However, state-of-the-art models still struggle to generalize to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Peter Robicheaux , Matvei Popov , Anish Madan , Isaac Robinson , Joseph Nelson , Deva Ramanan , Neehar Peri

In this paper, we examine the recent Segment Anything Model (SAM) on medical images, and report both quantitative and qualitative zero-shot segmentation results on nine medical image segmentation benchmarks, covering various imaging…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Peilun Shi , Jianing Qiu , Sai Mu Dalike Abaxi , Hao Wei , Frank P. -W. Lo , Wu Yuan

Paleoradiology, the use of modern imaging technologies to study archaeological and anthropological remains, offers new windows on millennial scale patterns of human health. Unfortunately, the radiographs collected during field campaigns are…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Owen Dong , Lily Gao , Manish Kota , Bennett A. Landmana , Jelena Bekvalac , Gaynor Western , Katherine D. Van Schaik

Accurate annotation of cutaneous neoplasm biopsies represents a major challenge due to their wide morphological variability, overlapping histological patterns, and the subtle distinctions between benign and malignant lesions.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Santiago Moreno , Pablo Meseguer , Rocío del Amor , Valery Naranjo
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