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Classification of gigapixel Whole Slide Images (WSIs) is an important prediction task in the emerging area of computational pathology. There has been a surge of research in deep learning models for WSI classification with clinical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-04 Sajid Javed , Arif Mahmood , Talha Qaiser , Naoufel Werghi , Nasir Rajpoot

As the frontline data for cancer diagnosis, microscopic pathology images are fundamental for providing patients with rapid and accurate treatment. However, despite their practical value, the deep learning community has largely overlooked…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Sungrae Hong , Hyeongmin Park , Youngsin Ko , Sol Lee , Bryan Wong , Mun Yong Yi

In digital pathology, whole slide images (WSIs) are widely used for applications such as cancer diagnosis and prognosis prediction. Visual transformer models have recently emerged as a promising method for encoding large regions of WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Shuai Jiang , Liesbeth Hondelink , Arief A. Suriawinata , Saeed Hassanpour

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

The aim of this study is to propose an alternative and hybrid solution method for diagnosing the disease from histopathology images taken from animals with paratuberculosis and intact intestine. In detail, the hybrid method is based on…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Nilgun Sengoz , Tuncay Yigit , Ozlem Ozmen , Ali Hakan Isik

This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Hassan Keshvarikhojasteh , Josien Pluim , Mitko Veta

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Accurate automated segmentation of tibial plateau fractures (TPF) from computed tomography (CT) requires large amounts of annotated data to train deep learning models, but obtaining such annotations presents unique challenges. The process…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Peiyan Yue , Die Cai , Chu Guo , Mengxing Liu , Jun Xia , Yi Wang

The application of deep learning to pathology assumes the existence of digital whole slide images of pathology slides. However, slide digitization is bottlenecked by the high cost of precise motor stages in slide scanners that are needed…

Image and Video Processing · Electrical Eng. & Systems 2020-11-13 Viswesh Krishna , Anirudh Joshi , Philip L. Bulterys , Eric Yang , Andrew Y. Ng , Pranav Rajpurkar

Deep learning developments have improved medical imaging diagnoses dramatically, increasing accuracy in several domains. Nonetheless, obstacles continue to exist because of the requirement for huge datasets and legal limitations on data…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Ivan Reyes-Amezcua , Michael Rojas-Ruiz , Gilberto Ochoa-Ruiz , Andres Mendez-Vazquez , Christian Daul

Needle positioning is essential for various medical applications such as epidural anaesthesia. Physicians rely on their instincts while navigating the needle in epidural spaces. Thereby, identifying the tissue structures may be helpful to…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Debayan Bhattacharya , Sarah Latus , Finn Behrendt , Florin Thimm , Dennis Eggert , Christian Betz , Alexander Schlaefer

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Accurate and efficient cell detection is crucial in many biomedical image analysis tasks. We evaluate the performance of several Deep Learning (DL) methods for cell detection in Papanicolaou-stained cytological Whole Slide Images (WSIs),…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Marco Acerbis , Nataša Sladoje , Joakim Lindblad

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Deep learning models for medical image classification usually achieve promising results but typically rely on large, annotated datasets or standard transfer learning from ImageNet. Self-Supervised Learning (SSL) has emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Joao Batista Florindo , Amanda Pontes de Oliveira Ornelas

Fine-grained image classification is to recognize hundreds of subcategories in each basic-level category. Existing methods employ discriminative localization to find the key distinctions among subcategories. However, they generally have two…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Xiangteng He , Yuxin Peng , Junjie Zhao

Accurate segmentation of multiple organs in Computed Tomography (CT) images plays a vital role in computer-aided diagnosis systems. While various supervised learning approaches have been proposed recently, these methods heavily depend on a…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Yongzhi Huang , Fengjun Xi , Liyun Tu , Jinxin Zhu , Haseeb Hassan , Liyilei Su , Yun Peng , Jingyu Li , Jun Ma , Bingding Huang

Cribriform growth patterns in prostate carcinoma are associated with poor prognosis. We aimed to introduce a deep learning method to detect such patterns automatically. To do so, convolutional neural network was trained to detect cribriform…

Image and Video Processing · Electrical Eng. & Systems 2020-09-14 Pierre Ambrosini , Eva Hollemans , Charlotte F. Kweldam , Geert J. L. H. van Leenders , Sjoerd Stallinga , Frans Vos