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Current methods for learning graphical models with latent variables and a fixed structure estimate optimal values for the model parameters. Whereas this approach usually produces overfitting and suboptimal generalization performance,…

Machine Learning · Computer Science 2013-01-30 Hagai Attias

In this paper, we consider the problem of parametric empirical Bayes estimation of an i.i.d. prior in high-dimensional Bayesian linear regression, with random design. We obtain the asymptotic distribution of the variational Empirical Bayes…

Statistics Theory · Mathematics 2026-02-25 Seunghyun Lee , Nabarun Deb

We develop a variational Bayes approach for dynamic variable selection in high-dimensional regression models with time-varying parameters and predictors that exhibit a predefined group structure. Through comprehensive simulation studies, we…

Methodology · Statistics 2025-04-16 Nicolas Bianco , Mauro Bernardi , Daniele Bianchi

Shrinkage estimators that possess the ability to produce sparse solutions have become increasingly important to the analysis of today's complex datasets. Examples include the LASSO, the Elastic-Net and their adaptive counterparts.…

Methodology · Statistics 2017-02-09 Hongmei Liu , J. Sunil Rao

Due to its low computational cost, Lasso is an attractive regularization method for high-dimensional statistical settings. In this paper, we consider multivariate counting processes depending on an unknown function parameter to be estimated…

Statistics Theory · Mathematics 2015-04-08 Niels Richard Hansen , Patricia Reynaud-Bouret , Vincent Rivoirard

Variable selection in linear regression settings is a much discussed problem. Best subset selection (BSS) is often considered the intuitive 'gold standard', with its use being restricted only by its NP-hard nature. Alternatives such as the…

Methodology · Statistics 2023-02-24 Moritz Hanke , Louis Dijkstra , Ronja Foraita , Vanessa Didelez

In high-dimensional statistical inference in which the number of parameters to be estimated is larger than that of the holding data, regularized linear estimation techniques are widely used. These techniques have, however, some drawbacks.…

Methodology · Statistics 2025-08-06 Takashi Takahashi , Yoshiyuki Kabashima

High-dimensional signal recovery of standard linear regression is a key challenge in many engineering fields, such as, communications, compressed sensing, and image processing. The approximate message passing (AMP) algorithm proposed by…

Information Theory · Computer Science 2022-03-02 Qiuyun Zou , Hongwen Yang

Linear mixed models are a versatile statistical tool to study data by accounting for fixed effects and random effects from multiple sources of variability. In many situations, a large number of candidate fixed effects is available and it is…

Methodology · Statistics 2022-09-09 Emanuele Degani , Luca Maestrini , Dorota Toczydłowska , Matt P. Wand

This paper studies schemes to de-bias the Lasso in a linear model $y=X\beta+\epsilon$ where the goal is to construct confidence intervals for $a_0^T\beta$ in a direction $a_0$, where $X$ has iid $N(0,\Sigma)$ rows. We show that previously…

Statistics Theory · Mathematics 2021-07-09 Pierre C. Bellec , Cun-Hui Zhang

Transfer learning techniques aim to leverage information from multiple related datasets to enhance prediction quality against a target dataset. Such methods have been adopted in the context of high-dimensional sparse regression, and some…

Machine Learning · Statistics 2025-01-31 Koki Okajima , Tomoyuki Obuchi

A novel data-driven methodology is presented for the joint selection of prior parameters for both fixed and random effects in Linear Mixed Models (LMMs). This approach facilitates the estimation of complex random-effects structures, as well…

Methodology · Statistics 2026-04-28 Matteo Amestoy , R. Vermeulen , Mark A. van de Wiel , Wessel N. van Wieringen

We study the asymptotic properties of Lasso+mLS and Lasso+Ridge under the sparse high-dimensional linear regression model: Lasso selecting predictors and then modified Least Squares (mLS) or Ridge estimating their coefficients. First, we…

Statistics Theory · Mathematics 2014-01-14 Hanzhong Liu , Bin Yu

Histogram-based empirical Bayes methods developed for analyzing data for large numbers of genes, SNPs, or other biological features tend to have large biases when applied to data with a smaller number of features such as genes with…

Methodology · Statistics 2013-10-10 Marta Padilla , David R. Bickel

We study the problem of exact support recovery for high-dimensional sparse linear regression under independent Gaussian design when the signals are weak, rare, and possibly heterogeneous. Under a suitable scaling of the sample size and…

Statistics Theory · Mathematics 2023-07-19 Saptarshi Roy , Ambuj Tewari , Ziwei Zhu

We develop a novel Empirical Bayes methodology for prediction under check loss in high-dimensional Gaussian models. The check loss is a piecewise linear loss function having differential weights for measuring the amount of underestimation…

Statistics Theory · Mathematics 2016-06-24 Gourab Mukherjee , Lawrence D. Brown , Paat Rusmevichientong

Inverse probability weighted estimators are the oldest and potentially most commonly used class of procedures for the estimation of causal effects. By adjusting for selection biases via a weighting mechanism, these procedures estimate an…

Methodology · Statistics 2021-07-06 Ashkan Ertefaie , Nima S. Hejazi , Mark J. van der Laan

Recently, considerable interest has focused on variable selection methods in regression situations where the number of predictors, $p$, is large relative to the number of observations, $n$. Two commonly applied variable selection approaches…

Applications · Statistics 2011-04-19 Peter Radchenko , Gareth M. James

Effect modification occurs when the effect of the treatment on an outcome varies according to the level of other covariates and often has important implications in decision making. When there are tens or hundreds of covariates, it becomes…

Methodology · Statistics 2021-11-23 Qingyuan Zhao , Dylan S. Small , Ashkan Ertefaie

The popularity of penalized regression in high-dimensional data analysis has led to a demand for new inferential tools for these models. False discovery rate control is widely used in high-dimensional hypothesis testing, but has only…

Methodology · Statistics 2019-01-24 Ryan Miller , Patrick Breheny
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