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Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

Information Retrieval · Computer Science 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

A dynamic treatment regime is a sequence of medical decisions that adapts to the evolving clinical status of a patient over time. To facilitate personalized care, it is crucial to assess the probability of each available treatment option…

Methodology · Statistics 2024-11-05 Jiefeng Bi , Matteo Borrotti , Bernardo Nipoti

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical…

Machine Learning · Computer Science 2025-12-15 Jiang Liu , Yujie Li , Chan Zhou , Yihao Xie , Qilong Sun , Xin Shu , Peiwei Li , Chunyong Yang , Yiziting Zhu , Jiaqi Zhu , Yuwen Chen , Bo An , Hao Wu , Bin Yi

Causal inference is paramount for understanding the effects of interventions, yet extracting personalized insights from increasingly complex data remains a significant challenge for modern machine learning. This is the case, in particular,…

Methodology · Statistics 2026-02-12 Filippo Salmaso , Lorenzo Testa , Francesca Chiaromonte

The use of machine learning (ML) in high-stakes societal decisions has encouraged the consideration of fairness throughout the ML lifecycle. Although data integration is one of the primary steps to generate high quality training data, most…

Machine Learning · Computer Science 2022-04-01 Sainyam Galhotra , Karthikeyan Shanmugam , Prasanna Sattigeri , Kush R. Varshney

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

Machine Learning · Computer Science 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid (the UDCA response) accurately predicts long-term outcome. In this study we sought to use liver…

An individualized dose rule recommends a dose level within a continuous safe dose range based on patient level information such as physical conditions, genetic factors and medication histories. Traditionally, personalized dose finding…

Methodology · Statistics 2020-07-21 Liangyu Zhu , Wenbin Lu , Michael R. Kosorok , Rui Song

With the recent paradigm shift from cytotoxic drugs to new generation of target therapy and immuno-oncology therapy during oncology drug developments, patients with various cancer (sub)types may be eligible to participate in a basket trial…

Methodology · Statistics 2026-05-12 Junxian Geng , Tianjian Zhou , Ruitao Lin , Guanyu Hu

Deep neural networks has been increasingly applied in fault diagnostics, where it uses historical data to capture systems behavior, bypassing the need for high-fidelity physical models. However, despite their competence in prediction tasks,…

Machine Learning · Computer Science 2025-09-24 Arman Mohammadi , Mattias Krysander , Daniel Jung , Erik Frisk

Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Huan Zheng , Yucheng Zhou , Tianyi Yan , Dubing Chen , Hongbo Lu , Wenlong Liao , Tao He , Pai Peng , Jianbing Shen

Medical multi-modal pre-training has revealed promise in computer-aided diagnosis by leveraging large-scale unlabeled datasets. However, existing methods based on masked autoencoders mainly rely on data-level reconstruction tasks, but lack…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yupei Zhang , Li Pan , Qiushi Yang , Tan Li , Zhen Chen

Optimizing credit limits, interest rates, and loan terms is crucial for managing borrower risk and lifetime value (LTV) in personal loan platform. However, counterfactual estimation of these continuous, multi-dimensional treatments faces…

Machine Learning · Computer Science 2025-08-12 Kexin Zhao , Bo Wang , Cuiying Zhao , Tongyao Wan

The present research tackles the difficulty of predicting osteoporosis risk via machine learning (ML) approaches, emphasizing the use of explainable artificial intelligence (XAI) to improve model transparency. Osteoporosis is a significant…

Machine Learning · Computer Science 2025-10-03 Farhana Elias , Md Shihab Reza , Muhammad Zawad Mahmud , Samiha Islam , Shahran Rahman Alve

Accurate classification of computed tomography (CT) images is essential for diagnosis and treatment planning, but existing methods often struggle with the subtle and spatially diverse nature of pathological features. Current approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-07-21 Shravan Venkatraman , Pavan Kumar S , Rakesh Raj Madavan , Chandrakala S

This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of…

Finding patient subgroups with similar characteristics is crucial for personalized decision-making in various disciplines such as healthcare and policy evaluation. While most existing approaches rely on unsupervised clustering methods,…

Machine Learning · Statistics 2026-03-06 Luwei Wang , Nazir Lone , Sohan Seth

Machine learning (ML) holds great promise for improving healthcare, but it is critical to ensure that its use will not propagate or amplify health disparities. An important step is to characterize the (un)fairness of ML models - their…

Machine Learning · Computer Science 2023-08-09 Alexander Brown , Nenad Tomasev , Jan Freyberg , Yuan Liu , Alan Karthikesalingam , Jessica Schrouff

Objective: The objective of this study is to develop a machine learning (ML)-based framework for early risk stratification of clinical trials (CTs) according to their likelihood of exhibiting a high rate of dosing errors, using information…

Machine Learning · Computer Science 2026-02-27 Félicien Hêche , Sohrab Ferdowsi , Anthony Yazdani , Sara Sansaloni-Pastor , Douglas Teodoro

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

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