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Artificial intelligence (AI) solutions that automatically extract information from digital histology images have shown great promise for improving pathological diagnosis. Prior to routine use, it is important to evaluate their predictive…

With the broad application of deep neural networks (DNNs), backdoor attacks have gradually attracted attention. Backdoor attacks are insidious, and poisoned models perform well on benign samples and are only triggered when given specific…

Machine Learning · Computer Science 2022-07-12 Chang Yue , Peizhuo Lv , Ruigang Liang , Kai Chen

Current metagenomic analysis algorithms require significant computing resources, can report excessive false positives (type I errors), may miss organisms (type II errors / false negatives), or scale poorly on large datasets. This paper…

Databases · Computer Science 2015-01-23 Ashley Mae Conard , Stephanie Dodson , Jeremy Kepner , Darrell Ricke

Large Language Models (LLMs) have transformed natural language processing (NLP) by enabling robust text generation and understanding. However, their deployment in sensitive domains like healthcare, finance, and legal services raises…

Artificial Intelligence · Computer Science 2024-12-09 Georgios Feretzakis , Vassilios S. Verykios

Fault-tolerant deep learning accelerator is the basis for highly reliable deep learning processing and critical to deploy deep learning in safety-critical applications such as avionics and robotics. Since deep learning is known to be…

Hardware Architecture · Computer Science 2023-12-22 Qing Zhang , Cheng Liu , Bo Liu , Haitong Huang , Ying Wang , Huawei Li , Xiaowei Li

Control evaluations measure whether monitoring and security protocols for AI systems prevent intentionally subversive AI models from causing harm. Our work presents the first control evaluation performed in an agent environment. We…

Machine Learning · Computer Science 2025-04-15 Aryan Bhatt , Cody Rushing , Adam Kaufman , Tyler Tracy , Vasil Georgiev , David Matolcsi , Akbir Khan , Buck Shlegeris

Sharing health and behavioral data raises significant privacy concerns, as conventional de-identification methods are susceptible to privacy attacks. Differential Privacy (DP) provides formal guarantees against re-identification risks, but…

The growing reliance of intelligent systems on data makes the systems vulnerable to data poisoning attacks. Such attacks could compromise machine learning or deep learning models by disrupting the input data. Previous studies on data…

Optimization and Control · Mathematics 2025-05-19 Xin Wang , Feilong Wang , Yuan Hong , R. Tyrrell Rockafellar , Xuegang , Ban

The wide use of machine learning is fundamentally changing the software development paradigm (a.k.a. Software 2.0) where data becomes a first-class citizen, on par with code. As machine learning is used in sensitive applications, it becomes…

Databases · Computer Science 2019-04-25 Ki Hyun Tae , Yuji Roh , Young Hun Oh , Hyunsu Kim , Steven Euijong Whang

Research into AI alignment has grown considerably since the recent introduction of increasingly capable Large Language Models (LLMs). Unfortunately, modern methods of alignment still fail to fully prevent harmful responses when models are…

Cryptography and Security · Computer Science 2024-08-20 Matthew Pisano , Peter Ly , Abraham Sanders , Bingsheng Yao , Dakuo Wang , Tomek Strzalkowski , Mei Si

Double machine learning (DML) has become an increasingly popular tool for automated variable selection in high-dimensional settings. Even though the ability to deal with a large number of potential covariates can render…

Econometrics · Economics 2023-05-25 Paul Hünermund , Beyers Louw , Itamar Caspi

The expanding role of Artificial Intelligence (AI) in diverse engineering domains highlights the challenges associated with deploying AI models in new operational environments, involving substantial investments in data collection and model…

Artificial Intelligence · Computer Science 2024-05-14 Daryl Mupupuni , Anupama Guntu , Liang Hong , Kamrul Hasan , Leehyun Keel

Leveraging real-world health data for machine learning tasks requires addressing many practical challenges, such as distributed data silos, privacy concerns with creating a centralized database from person-specific sensitive data, resource…

Machine Learning · Computer Science 2020-02-28 Olivia Choudhury , Aris Gkoulalas-Divanis , Theodoros Salonidis , Issa Sylla , Yoonyoung Park , Grace Hsu , Amar Das

Low-quality data can cause downstream problems in high-stakes applications. Data-centric approach emphasizes on improving dataset quality to enhance model performance. High-quality datasets are needed for general-purpose Large Language…

Computation and Language · Computer Science 2023-10-13 Iva Bojic , Josef Halim , Verena Suharman , Sreeja Tar , Qi Chwen Ong , Duy Phung , Mathieu Ravaut , Shafiq Joty , Josip Car

When selecting data for training large-scale models, standard practice is to filter for examples that match human notions of data quality. Such filtering yields qualitatively clean datapoints that intuitively should improve model behavior.…

Machine Learning · Computer Science 2024-01-24 Logan Engstrom , Axel Feldmann , Aleksander Madry

Clinical trials are pivotal for developing new medical treatments but typically carry risks such as patient mortality and enrollment failure that waste immense efforts spanning over a decade. Applying artificial intelligence (AI) to predict…

As Large Language Models (LLMs) and generative AI become more widespread, the content safety risks associated with their use also increase. We find a notable deficiency in high-quality content safety datasets and benchmarks that…

Machine Learning · Computer Science 2024-09-12 Shaona Ghosh , Prasoon Varshney , Erick Galinkin , Christopher Parisien

Backdoor attacks are emerging threats to deep neural networks, which typically embed malicious behaviors into a victim model by injecting poisoned samples. Adversaries can activate the injected backdoor during inference by presenting the…

Cryptography and Security · Computer Science 2025-12-05 Bingyin Zhao , Yingjie Lao

Machine learning has revolutionized numerous domains, playing a crucial role in driving advancements and enabling data-centric processes. The significance of data in training models and shaping their performance cannot be overstated. Recent…

Cryptography and Security · Computer Science 2024-10-01 Rui Wen , Michael Backes , Yang Zhang

As large language models (LLMs) are increasingly deployed in high-stakes settings, the risk of generating harmful or toxic content remains a central challenge. Post-hoc alignment methods are brittle: once unsafe patterns are learned during…