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The pace of scientific research, vital for improving human life, is complex, slow, and needs specialized expertise. Meanwhile, novel, impactful research often stems from both a deep understanding of prior work, and a cross-pollination of…

Computation and Language · Computer Science 2025-02-11 Jinheon Baek , Sujay Kumar Jauhar , Silviu Cucerzan , Sung Ju Hwang

The process of scientific discovery relies on an interplay of observations, analysis, and hypothesis generation. Machine learning is increasingly being adopted to address individual aspects of this process. However, it remains an open…

Artificial Intelligence · Computer Science 2026-05-26 Maximilian Nägele , Florian Marquardt

Understanding the world and explaining it with scientific theories is a central aspiration of artificial intelligence research. Proposing theories, designing experiments to test them, and then revising them based on data are fundamental to…

Machine Learning · Computer Science 2025-10-16 Kanishk Gandhi , Michael Y. Li , Lyle Goodyear , Agam Bhatia , Louise Li , Aditi Bhaskar , Mohammed Zaman , Noah D. Goodman

This paper introduces a methodology based on agentic workflows for economic research that leverages Large Language Models (LLMs) and multimodal AI to enhance research efficiency and reproducibility. Our approach features autonomous and…

General Economics · Economics 2025-04-15 Herbert Dawid , Philipp Harting , Hankui Wang , Zhongli Wang , Jiachen Yi

Large language models (LLMs) have grown in their usage to provide support for question answering across numerous disciplines. The models on their own have already shown promise for answering basic questions, however fail quickly where…

Information Retrieval · Computer Science 2025-04-15 David Brett , Anniek Myatt

Hypothesis generation in biomedical research has traditionally centered on uncovering hidden relationships within vast scientific literature, often using methods like Literature-Based Discovery (LBD). Despite progress, current approaches…

Computation and Language · Computer Science 2025-11-13 Fuyi Yang , Chenchen Ye , Mingyu Derek Ma , Yijia Xiao , Matthew Yang , Wei Wang

Purpose: This paper introduces the concept of "Agentic Publication," a novel LLM-driven framework designed to complement traditional scientific publishing by transforming papers into interactive knowledge systems that address challenges…

Artificial Intelligence · Computer Science 2026-05-06 Roberto Pugliese , George Kourousias , Francesco Venier , Grazia Garlatti Costa

The rapid advancement of large language models (LLMs) has driven the development of agentic systems capable of autonomously performing complex tasks. Despite their impressive capabilities, LLMs remain constrained by their internal knowledge…

Information Retrieval · Computer Science 2025-08-19 Wenlin Zhang , Xiaopeng Li , Yingyi Zhang , Pengyue Jia , Yichao Wang , Huifeng Guo , Yong Liu , Xiangyu Zhao

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by grounding responses with retrieved information. As an emerging paradigm, Agentic RAG further enhances this process by introducing autonomous LLM agents into the…

Information Retrieval · Computer Science 2025-05-26 Yunjia Xi , Jianghao Lin , Menghui Zhu , Yongzhao Xiao , Zhuoying Ou , Jiaqi Liu , Tong Wan , Bo Chen , Weiwen Liu , Yasheng Wang , Ruiming Tang , Weinan Zhang , Yong Yu

As scientific research becomes increasingly complex, innovative tools are needed to manage vast data, facilitate interdisciplinary collaboration, and accelerate discovery. Large language models (LLMs) are now evolving into LLM-based…

Artificial Intelligence · Computer Science 2026-02-03 Shuo Ren , Can Xie , Pu Jian , Zhenjiang Ren , Chunlin Leng , Jiajun Zhang

Recent agent frameworks and inference-time algorithms often struggle with complex planning problems due to limitations in verifying generated plans or reasoning and varying complexity of instances within a single task. Many existing methods…

Agentic theorem provers combine a reasoning model, retrieval, search, and a proof assistant verifier, yet it remains unclear which components actually improve finite-budget proof success and why they help on real mathematical workloads. We…

Machine Learning · Statistics 2026-05-26 Sho Sonoda , Shunta Akiyama , Yuya Uezato

A formal but intuitive framework is introduced to bridge the gap between data obtained from empirical studies and that generated by agent-based models. This is based on three key tenets. Firstly, a simulation can be given multiple formal…

Multiagent Systems · Computer Science 2013-02-21 Chih-Chun Chen

Current AI-powered research systems adopt a direct search-then-summarize paradigm that treats hypotheses as end products of scientific discovery. We argue this leaves a critical gap: hypotheses can serve a far more powerful role as…

Artificial Intelligence · Computer Science 2026-05-12 Michael Chin

Large language models (LLMs) are increasingly leveraged to empower autonomous agents to simulate human beings in various fields of behavioral research. However, evaluating their capacity to navigate complex social interactions remains a…

Computation and Language · Computer Science 2024-11-26 Xinyi Mou , Jingcong Liang , Jiayu Lin , Xinnong Zhang , Xiawei Liu , Shiyue Yang , Rong Ye , Lei Chen , Haoyu Kuang , Xuanjing Huang , Zhongyu Wei

The integration of Agentic AI into scientific discovery marks a new frontier in research automation. These AI systems, capable of reasoning, planning, and autonomous decision-making, are transforming how scientists perform literature…

Computation and Language · Computer Science 2025-03-13 Mourad Gridach , Jay Nanavati , Khaldoun Zine El Abidine , Lenon Mendes , Christina Mack

Predictions and generations from large language models are increasingly being explored as an aid in limited data regimes, such as in computational social science and human subjects research. While prior technical work has mainly explored…

Machine Learning · Computer Science 2025-10-09 Yewon Byun , Shantanu Gupta , Zachary C. Lipton , Rachel Leah Childers , Bryan Wilder

Large language models (LLMs) are increasingly used as simulated participants in social science experiments, but their behavior is often unstable and highly sensitive to design choices. Prior evaluations frequently conflate base-model…

Artificial Intelligence · Computer Science 2026-02-03 Xuan Liu , Haoyang Shang , Zizhang Liu , Xinyan Liu , Yunze Xiao , Yiwen Tu , Haojian Jin

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan,…

Reasoning about events and tracking their influences is fundamental to understanding processes. In this paper, we present EIGEN - a method to leverage pre-trained language models to generate event influences conditioned on a context, nature…

Computation and Language · Computer Science 2020-10-23 Aman Madaan , Dheeraj Rajagopal , Yiming Yang , Abhilasha Ravichander , Eduard Hovy , Shrimai Prabhumoye