English
Related papers

Related papers: Generative structural elucidation from mass spectr…

200 papers

Metal-organic frameworks (MOFs) are highly promising for carbon capture, yet navigating their vast design space remains challenging. Recent deep generative models enable de novo MOF design but primarily act as feed-forward structure…

Machine Learning · Computer Science 2026-04-16 Chaoran Zhang , Guangyao Li , Dongxu Ji

Designing fluorescent small molecules with tailored optical and physicochemical properties requires navigating vast, underexplored chemical space while satisfying multiple objectives and constraints. Conventional generate-score-screen…

Machine Learning · Computer Science 2026-01-21 Yanheng Li , Zhichen Pu , Lijiang Yang , Zehao Zhou , Yi Qin Gao

With the development of underwater exploration and marine protection, underwater vision tasks are widespread. Due to the degraded underwater environment, characterized by color distortion, low contrast, and blurring, camouflaged instance…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Chuhong Wang , Hua Li , Chongyi Li , Huazhong Liu , Xiongxin Tang , Sam Kwong

Changes in the number of copies of certain parts of the genome, known as copy number alterations (CNAs), due to somatic mutation processes are a hallmark of many cancers. This genomic complexity is known to be associated with poorer…

Genomics · Quantitative Biology 2024-08-26 Charles Gadd , Christopher Yau

The computational prediction of the structure and stability of hybrid organic-inorganic interfaces provides important insights into the measurable properties of electronic thin film devices, coatings, and catalyst surfaces and plays an…

Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful and widely used tools for molecular structure elucidation in organic chemistry. However, the interpretation of NMR spectra to determine unknown molecular structures…

Chemical Physics · Physics 2025-09-03 Yongqi Jin , Jun-Jie Wang , Fanjie Xu , Xiaohong Ji , Zhifeng Gao , Linfeng Zhang , Guolin Ke , Rong Zhu , Weinan E

Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) is a cornerstone in biomolecular analysis, offering precise identification of pathogens through unique mass spectral signatures. Yet, its reliance on labor-intensive…

Machine Learning · Computer Science 2025-11-24 Kyle M. Regan , Michael McLoughlin , Wayne A. Bryden , Gonzalo R. Arce

Large Language Models (LLMs) are unable to reliably reason about specific physical systems. Attempts to imbue LLMs with knowledge of the necessary physics concepts have shown great promise, but explainability and validation remain open…

Artificial Intelligence · Computer Science 2026-05-22 Sean Memery , Kartic Subr

We address the task of controlled generation of small molecules, which entails finding novel molecules with desired properties under certain constraints (e.g., similarity to a reference molecule). Here we introduce MolMIM, a probabilistic…

Machine Learning · Computer Science 2023-03-31 Danny Reidenbach , Micha Livne , Rajesh K. Ilango , Michelle Gill , Johnny Israeli

Evolutionary algorithms (EAs) have proven effective in exploring the vast solution spaces typical of graph-structured combinatorial problems. However, traditional encoding schemes, such as binary or numerical representations, often fail to…

Neural and Evolutionary Computing · Computer Science 2025-10-28 Jie Zhao , Kang Hao Cheong

Current multi-agent systems (MAS) frameworks often rely on manually designed and static collaboration graph structures, limiting adaptability and performance. To address these limitations, we propose DynaSwarm, a dynamic framework that…

Machine Learning · Computer Science 2025-08-13 Hui Yi Leong , Yuqing Wu

Recent advances in artificial intelligence have propelled the development of innovative computational materials modeling and design techniques. Generative deep learning models have been used for molecular representation, discovery, and…

Chemical Physics · Physics 2021-02-12 Navid Shervani-Tabar , Nicholas Zabaras

Clinical trials require strict adherence to medication protocols, yet dosing errors remain a persistent challenge affecting patient safety and trial integrity. We present an automated system for detecting dosing errors in unstructured…

Artificial Intelligence · Computer Science 2026-04-23 Mohammad AL-Smadi

Large language models (LLMs) show promise for automated code optimization. However, without performance context, they struggle to produce correct and effective code transformations. Existing performance tools can identify bottlenecks but…

Performance · Computer Science 2026-04-28 Mohammad Zaeed , Tanzima Z. Islam , Vladimir Indic

Molecular dynamics (MD) simulations are useful in obtaining thermodynamic and kinetic properties of bio-molecules but are limited by the timescale barrier, i.e., we may be unable to efficiently obtain properties because we need to run…

Chemical Physics · Physics 2017-08-23 Surl-Hee Ahn , Jay W. Grate , Eric F. Darve

Molecular optimization (MO) is a crucial stage in drug discovery in which task-oriented generated molecules are optimized to meet practical industrial requirements. Existing mainstream MO approaches primarily utilize external property…

Machine Learning · Computer Science 2025-12-17 Yida Xiong , Kun Li , Jiameng Chen , Hongzhi Zhang , Di Lin , Yan Che , Wenbin Hu

Combining machine learning (ML) with computational fluid dynamics (CFD) opens many possibilities for improving simulations of technical and natural systems. However, CFD+ML algorithms require exchange of data, synchronization, and…

Machine Learning · Computer Science 2024-06-25 Tomislav Maric , Mohammed Elwardi Fadeli , Alessandro Rigazzi , Andrew Shao , Andre Weiner

One of the main challenges in simultaneous localization and mapping (SLAM) is real-time processing. High-computational loads linked to data acquisition and processing complicate this task. This article presents an efficient feature…

Token-based masked generative models are gaining popularity for their fast inference time with parallel decoding. While recent token-based approaches achieve competitive performance to diffusion-based models, their generation performance is…

Machine Learning · Computer Science 2023-04-05 Jaewoong Lee , Sangwon Jang , Jaehyeong Jo , Jaehong Yoon , Yunji Kim , Jin-Hwa Kim , Jung-Woo Ha , Sung Ju Hwang

Ultrasound Localization Microscopy (ULM) enables imaging of vascular structures in the micrometer range by accumulating contrast agent particle locations over time. Precise and efficient target localization accuracy remains an active…

Image and Video Processing · Electrical Eng. & Systems 2023-11-08 Christopher Hahne , Georges Chabouh , Olivier Couture , Raphael Sznitman