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This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed…

Information Theory · Computer Science 2026-05-08 Serge Kas Hanna

DNA data storage systems encode digital data into DNA strands, enabling dense and durable storage. Efficient data retrieval depends on coverage depth, a key performance metric. We study the random access coverage depth problem and focus on…

Information Theory · Computer Science 2025-07-29 Şeyma Bodur , Stefano Lia , Hiram H. López , Rati Ludhani , Alberto Ravagnani , Lisa Seccia

DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced…

Information Theory · Computer Science 2024-03-13 Daniella Bar-Lev , Itai Orr , Omer Sabary , Tuvi Etzion , Eitan Yaakobi

Distributed storage systems provide reliable access to data through redundancy spread over individually unreliable nodes. Application scenarios include data centers, peer-to-peer storage systems, and storage in wireless networks. Storing…

Networking and Internet Architecture · Computer Science 2008-03-06 Alexandros G. Dimakis , P. Brighten Godfrey , Yunnan Wu , Martin J. Wainwright , Kannan Ramchandran

In this review paper, we delve into the nascent field of molecular data storage, focusing on system implementations and code constructions. We start by providing an overview of basic concepts in synthetic and computational biology.…

Emerging Technologies · Computer Science 2023-10-10 Olgica Milenkovic , Chao Pan

The DNA storage channel is considered, in which a codeword is comprised of $M$ unordered DNA molecules. At reading time, $N$ molecules are sampled with replacement, and then each molecule is sequenced. A coded-index concatenated-coding…

Information Theory · Computer Science 2022-05-23 Nir Weinberger

Distributed storage systems often introduce redundancy to increase reliability. When coding is used, the repair problem arises: if a node storing encoded information fails, in order to maintain the same level of reliability we need to…

Information Theory · Computer Science 2010-04-27 Alexandros G. Dimakis , Kannan Ramchandran , Yunnan Wu , Changho Suh

Regenerating codes are a class of codes proposed for providing reliability of data and efficient repair of failed nodes in distributed storage systems. In this paper, we address the fundamental problem of handling errors and erasures during…

Information Theory · Computer Science 2015-03-20 K. V. Rashmi , Nihar B. Shah , Kannan Ramchandran , P. Vijay Kumar

In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

Information Theory · Computer Science 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

DNA-based storage is an emerging storage technology that provides high information density and long duration. Due to the physical constraints in the reading and writing processes, error correction in DNA storage poses several interesting…

Information Theory · Computer Science 2023-10-04 Jin Sima , Netanel Raviv , Moshe Schwartz , Jehoshua Bruck

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

Information Retrieval · Computer Science 2022-10-21 Yun Qin , Fei Zhu , Bo Xi

Owing to its longevity and enormous information density, DNA, the molecule encoding biological information, has emerged as a promising archival storage medium. However, due to technological constraints, data can only be written onto many…

Emerging Technologies · Computer Science 2018-03-12 Reinhard Heckel , Gediminas Mikutis , Robert N. Grass

Erasure coding techniques are getting integrated in networked distributed storage systems as a way to provide fault-tolerance at the cost of less storage overhead than traditional replication. Redundancy is maintained over time through…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-06-12 Lluis Pamies-Juarez , Frédérique Oggier , Anwitaman Datta

DNA is emerging as an increasingly attractive medium for data storage due to a number of important and unique advantages it offers, most notably the unprecedented durability and density. While the technology is evolving rapidly, the…

Emerging Technologies · Computer Science 2022-05-03 Dehui Lin , Yasamin Tabatabaee , Yash Pote , Djordje Jevdjic

In a distributed storage system, code symbols are dispersed across space in nodes or storage units as opposed to time. In settings such as that of a large data center, an important consideration is the efficient repair of a failed node.…

Information Theory · Computer Science 2018-06-13 S. B. Balaji , M. Nikhil Krishnan , Myna Vajha , Vinayak Ramkumar , Birenjith Sasidharan , P. Vijay Kumar

We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

Information Theory · Computer Science 2024-06-21 Lorenz Welter , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

The DNA storage channel is considered, in which the $M$ Deoxyribonucleic acid (DNA) molecules comprising each codeword are stored without order, sampled $N$ times with replacement, and then sequenced over a discrete memoryless channel. For…

Information Theory · Computer Science 2022-02-15 Nir Weinberger , Neri Merhav

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen

DNA storage is a promising archival data storage solution to today's big data problem. A DNA storage system encodes and stores digital data with synthetic DNA sequences and decodes DNA sequences back to digital data via sequencing. For…

Emerging Technologies · Computer Science 2024-03-22 Yixun Wei , Wenlong Wang , Huibing Dong , Bingzhe Li , David Du

This chapter deals with the topic of designing reliable and efficient codes for the storage and retrieval of large quantities of data over storage devices that are prone to failure. For long, the traditional objective has been one of…

Information Theory · Computer Science 2020-10-06 Vinayak Ramkumar , Myna Vajha , S. B. Balaji , M. Nikhil Krishnan , Birenjith Sasidharan , P. Vijay Kumar
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