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Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…
Deep learning approaches for diffusion MRI have so far focused primarily on voxel-based segmentation of lesions or white-matter fiber tracts. A drawback of representing tracts as volumetric labels, rather than sets of streamlines, is that…
Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…
EEG-correlated fMRI analysis is widely used to detect regional blood oxygen level dependent fluctuations that are significantly synchronized to interictal epileptic discharges, which can provide evidence for localizing the ictal onset zone.…
Several gene-based association tests for time-to-event traits have been proposed recently, to detect whether a gene region (containing multiple variants), as a set, is associated with the survival outcome. However, for bivariate survival…
Acute stroke lesion segmentation tasks are of great clinical interest as they can help doctors make better informed treatment decisions. Magnetic resonance imaging (MRI) is time demanding but can provide images that are considered gold…
Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…
Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…
Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to…
In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…
EEG-based emotion recognition holds significant potential in the field of brain-computer interfaces. A key challenge lies in extracting discriminative spatiotemporal features from electroencephalogram (EEG) signals. Existing studies often…
Mixed-signal neuromorphic processors with brain-like organization and device physics offer an ultra-low-power alternative to the unsustainable developments of conventional deep learning and computing. However, realizing the potential of…
This study presents a deep convolutional autoencoder network for filtering reverberation clutter from transthoracic echocardiographic (TTE) image sequences. Given the spatiotemporal nature of this type of clutter, the filtering network…
How to identify and characterize functional brain networks (BN) is fundamental to gain system-level insights into the mechanisms of brain organizational architecture. Current functional magnetic resonance (fMRI) analysis highly relies on…
Quantitative cardiac magnetic resonance T1 and T2 mapping enable myocardial tissue characterisation but the lengthy scan times restrict their widespread clinical application. We propose a deep learning method that incorporates a time…
Intracranial aneurysms pose a significant clinical risk yet are difficult to detect, delineate and model due to limited annotated 3D data. We propose a cross-domain feature-transfer approach that leverages the latent geometric embeddings…
With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…
Scalar features in time-dependent fluid flow are traditionally visualized using 3D representation, and their topology changes over time are often conveyed with abstract graphs. Using such techniques, however, the structural details of…
Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke and is characterized by a high incidence of disability. Accurate segmentation of the ICH region and prognosis prediction are critically important for developing and refining…
Different brain imaging modalities offer unique insights into brain function and structure. Combining them enhances our understanding of neural mechanisms. Prior multimodal studies fusing functional MRI (fMRI) and structural MRI (sMRI) have…