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Accurate segmentation of myocardial scar from late gadolinium enhanced (LGE) cardiac MRI is essential for evaluating tissue viability, yet remains challenging due to variable contrast and imaging artifacts. Electrocardiogram (ECG) signals…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Farheen Ramzan , Yusuf Kiberu , Nikesh Jathanna , Meryem Jabrane , Vicente Grau , Shahnaz Jamil-Copley , Richard H. Clayton , Chen , Chen

This technical note considers the problems of blind sparse learning and inference of electrogram (EGM) signals under atrial fibrillation (AF) conditions. First of all we introduce a mathematical model for the observed signals that takes…

Machine Learning · Statistics 2013-01-01 David Luengo , Javier Via , Sandra Monzon , Tom Trigano , Antonio Artes-Rodriguez

Electroencephalograms (EEG) are invaluable for treating neurological disorders, however, mapping EEG electrode readings to brain activity requires solving a challenging inverse problem. Due to the time series data, the use of $\ell_1$…

Machine Learning · Statistics 2025-02-28 Jack Michael Solomon , Rosemary Renaut , Matthias Chung

In this paper we develop theoretical analysis and numerical reconstruction techniques for the solution of an inverse boundary value problem dealing with the nonlinear, time-dependent monodomain equation, which models the evolution of the…

Analysis of PDEs · Mathematics 2017-01-27 Elena Beretta , Cecilia Cavaterra , Maria Cristina Cerutti , Andrea Manzoni , Luca Ratti

The inverse conductivity problem aims at determining the unknown conductivity inside a bounded domain from boundary measurements. In practical applications, algorithms based on minimizing a regularized residual functional subject to PDE…

Numerical Analysis · Mathematics 2025-10-02 Lefu Cai , Zhixin Liu , Minghui Song , Xianchao Wang

In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions.…

Machine Learning · Computer Science 2025-12-11 Yuhao Xu , Jiaying Lu , Sirui Ding , Defu Cao , Xiao Hu , Carl Yang

Dynamic inverse problems are challenging to solve due to the need to identify and incorporate appropriate regularization in both space and time. Moreover, the very large scale nature of such problems in practice presents an enormous…

Numerical Analysis · Mathematics 2025-01-23 Toluwani Okunola , Mirjeta Pasha , Misha Kilmer , Melina Freitag

Ultrasound elasticity images which enable the visualization of quantitative maps of tissue stiffness can be reconstructed by solving an inverse problem. Classical model-based approaches for ultrasound elastography use deterministic finite…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Narges Mohammadi , Marvin M. Doyley , Mujdat Cetin

Foundation models have recently gained significant attention because of their generalizability and adaptability across multiple tasks and data distributions. Although medical foundation models have emerged, solutions for cardiac imaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Sekeun Kim , Pengfei Jin , Sifan Song , Cheng Chen , Yiwei Li , Hui Ren , Xiang Li , Tianming Liu , Quanzheng Li

Learning spatial-temporal correspondences in cardiac motion from images is important for understanding the underlying dynamics of cardiac anatomical structures. Many methods explicitly impose smoothness constraints such as the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Xiaoran Zhang , Chenyu You , Shawn Ahn , Juntang Zhuang , Lawrence Staib , James Duncan

Noninvasive reconstruction of cardiac transmembrane potential (TMP) from surface electrocardiograms (ECG) involves an ill-posed inverse problem. Model-constrained regularization is powerful for incorporating rich physiological knowledge…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , Jwala Dhamala , Prashnna Kumar Gyawali , John L Sapp , B. Milan Horacek , Linwei Wang

The efficient construction of anatomical models is one of the major challenges of patient-specific in-silico models of the human heart. Current methods frequently rely on linear statistical models, allowing no advanced topological changes,…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Jan Verhülsdonk , Thomas Grandits , Francisco Sahli Costabal , Thomas Pinetz , Rolf Krause , Angelo Auricchio , Gundolf Haase , Simone Pezzuto , Alexander Effland

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

The forward problem in electrocardiology, computing body surface potentials from cardiac electrical activity, is traditionally solved using physics-based models such as the bidomain or monodomain equations. While accurate, these approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Shaheim Ogbomo-Harmitt , Cesare Magnetti , Chiara Spota , Jakub Grzelak , Oleg Aslanidi

In this work we develop and analyze an adaptive finite element method for efficiently solving electrical impedance tomography -- a severely ill-posed nonlinear inverse problem for recovering the conductivity from boundary voltage…

Numerical Analysis · Mathematics 2019-05-16 Bangti Jin , Yifeng Xu , Jun Zou

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

The Extracellular-Membrane-Intracellular (EMI) model is a novel mathematical framework for cardiac electrophysiology simulations. The EMI model provides a more detailed description of the heart's electrical activity compared to traditional…

Numerical Analysis · Mathematics 2025-04-29 Carlos Ballesteros , Alexei Cheviakov , Raymond J. Spiteri

Modeling the behavior of biological tissues and organs often necessitates the knowledge of their shape in the absence of external loads. However, when their geometry is acquired in-vivo through imaging techniques, bodies are typically…

Biological Physics · Physics 2024-02-27 N. A. Barnafi , F. Regazzoni , D. Riccobelli

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Jan Christoph , Jan Lebert

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert