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Logical reasoning is a fundamental capability of large language models. However, existing studies often overlook the interaction between logical complexity and semantic complexity, leading to systems that struggle with abstract…

Artificial Intelligence · Computer Science 2026-04-23 Yunyao Zhang , Xinglang Zhang , Junxi Sheng , Wenbing Li , Junqing Yu , Yi-Ping Phoebe Chen , Wei Yang , Zikai Song

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

Large Language Models (LLMs) are playing an increasingly important role in physics research by assisting with symbolic manipulation, numerical computation, and scientific reasoning. However, ensuring the reliability, transparency, and…

Artificial Intelligence · Computer Science 2025-08-19 Yinggan Xu , Hana Kimlee , Yijia Xiao , Di Luo

Feedback in cellular processes is typically inferred through cellular responses to experimental perturbations. Modular response analysis provides a theoretical framework for translating specific perturbations into feedback sensitivities…

Molecular Networks · Quantitative Biology 2025-05-09 Seshu Iyengar , Andreas Hilfinger

Large language models (LLMs) have large potential for molecular optimization, as they can gather external chemistry tools and enable collaborative interactions to iteratively refine molecular candidates. However, this potential remains…

Artificial Intelligence · Computer Science 2025-05-28 Hyomin Kim , Yunhui Jang , Sungsoo Ahn

Engineering biology requires precise control of biomolecular circuits, and Cybergenetics is the field dedicated to achieving this goal. A significant challenge in developing controllers for cellular functions is designing systems that can…

Quantitative Methods · Quantitative Biology 2024-09-18 Hamza Faquir , Manuel Pájaro , Irene Otero-Muras

Student simulation in online education is important to address dynamic learning behaviors of students with diverse backgrounds. Existing simulation models based on deep learning usually need massive training data, lacking prior knowledge in…

Computers and Society · Computer Science 2024-04-12 Songlin Xu , Xinyu Zhang , Lianhui Qin

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

Artificial Intelligence · Computer Science 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

Autonomous agents empowered by Large Language Models (LLMs) have undergone significant improvements, enabling them to generalize across a broad spectrum of tasks. However, in real-world scenarios, cooperation among individuals is often…

Multi-agent systems often operate under feedback, adaptation, and non-stationarity, yet many simulation studies retain static decision rules and fixed control parameters. This paper introduces a general adaptive multi-agent learning…

Multiagent Systems · Computer Science 2025-11-26 Roberto Garrone

The applications of large language models (LLMs) in various biological domains have been explored recently, but their reasoning ability in complex biological systems, such as pathways, remains underexplored, which is crucial for predicting…

Machine Learning · Computer Science 2025-07-23 Haiteng Zhao , Chang Ma , Fangzhi Xu , Lingpeng Kong , Zhi-Hong Deng

Language-driven generative agents have enabled large-scale social simulations with transformative uses, from interpersonal training to aiding global policy-making. However, recent studies indicate that generative agent behaviors often…

Computation and Language · Computer Science 2025-09-23 Yunzhe Wang , Gale M. Lucas , Burcin Becerik-Gerber , Volkan Ustun

Multi-agent LLM frameworks are widely used to accelerate the development of agent systems powered by large language models (LLMs). These frameworks impose distinct architectural structures that govern how agents interact, store information,…

Artificial Intelligence · Computer Science 2026-02-04 Abdelghny Orogat , Ana Rostam , Essam Mansour

Agricultural visual question answering is essential for providing farmers and researchers with accurate and timely knowledge. However, many existing approaches are predominantly developed for evidence-constrained settings such as text-only…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Yan Ke , Xin Yu , Heming Du , Scott Chapman , Helen Huang

Multi-agents has exhibited significant intelligence in real-word simulations with Large language models (LLMs) due to the capabilities of social cognition and knowledge retrieval. However, existing research on agents equipped with effective…

Artificial Intelligence · Computer Science 2025-04-23 Yajie Yu , Yue Feng

Large Language Models (LLMs) have shown remarkable reasoning capabilities in mathematical and scientific tasks. To enhance complex reasoning, multi-agent systems have been proposed to harness the collective intelligence of LLM agents.…

Artificial Intelligence · Computer Science 2025-10-22 Zhenyu Bi , Meng Lu , Yang Li , Swastik Roy , Weijie Guan , Morteza Ziyadi , Xuan Wang

We analyze the challenges of benchmarking scientific (multi)-agentic systems, including the difficulty of distinguishing reasoning from retrieval, the risks of data/model contamination, the lack of reliable ground truth for novel research…

Computers and Society · Computer Science 2026-04-07 Marcin Abram

Pharmaceutical patents play a vital role in biochemical industries, especially in drug discovery, providing researchers with unique early access to data, experimental results, and research insights. With the advancement of machine learning,…

Machine Learning · Computer Science 2024-10-30 Xin Wang , Yifan Zhang , Xiaojing Zhang , Longhui Yu , Xinna Lin , Jindong Jiang , Bin Ma , Kaicheng Yu

Risk management resulting from the actions and states of the different elements making up a operating room is a major concern during a surgical procedure. Agent-based simulation shows an interest through its interaction concepts,…

Artificial Intelligence · Computer Science 2020-07-23 Bruno Perez , Julien Henriet , Christophe Lang , Laurent Philippe

Large language models (LLMs) are increasingly used as simulated participants in social science experiments, but their behavior is often unstable and highly sensitive to design choices. Prior evaluations frequently conflate base-model…

Artificial Intelligence · Computer Science 2026-02-03 Xuan Liu , Haoyang Shang , Zizhang Liu , Xinyan Liu , Yunze Xiao , Yiwen Tu , Haojian Jin