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Gene-environment (G$\times$E) interactions have important implications to elucidate the etiology of complex diseases beyond the main genetic and environmental effects. Outliers and data contamination in disease phenotypes of G$\times$E…

Methodology · Statistics 2020-06-11 Jie Ren , Fei Zhou , Xiaoxi Li , Shuangge Ma , Yu Jiang , Cen Wu

Feature screening for ultra high dimensional feature spaces plays a critical role in the analysis of data sets whose predictors exponentially exceed the number of observations. Such data sets are becoming increasingly prevalent in areas…

Methodology · Statistics 2018-01-31 Randall Reese , Xiaotian Dai , Guifang Fu

Kernel methods offer the flexibility to learn complex relationships in modern, large data sets while enjoying strong theoretical guarantees on quality. Unfortunately, these methods typically require cubic running time in the data set size,…

Machine Learning · Statistics 2019-03-01 Raj Agrawal , Trevor Campbell , Jonathan H. Huggins , Tamara Broderick

This paper develops a framework for testing for associations in a possibly high-dimensional linear model where the number of features/variables may far exceed the number of observational units. In this framework, the observations are split…

Methodology · Statistics 2018-05-04 Rina Foygel Barber , Emmanuel J. Candes

Variable selection is of increasing importance to address the difficulties of high dimensionality in many scientific areas. In this paper, we demonstrate a property for distance covariance, which is incorporated in a novel feature screening…

Methodology · Statistics 2014-09-03 Jing Kong , Sijian Wang , Grace Wahba

Algorithms that ensure reproducible findings from large-scale, high-dimensional data are pivotal in numerous signal processing applications. In recent years, multivariate false discovery rate (FDR) controlling methods have emerged,…

Methodology · Statistics 2024-01-31 Jasin Machkour , Michael Muma , Daniel P. Palomar

This paper presents a novel deep learning based data-driven optimization method. A novel generative adversarial network (GAN) based data-driven distributionally robust chance constrained programming framework is proposed. GAN is applied to…

Optimization and Control · Mathematics 2020-05-12 Shipu Zhao , Fengqi You

We present a new simulation scheme which allows an efficient sampling of reconfigurable supramolecular structures made of polymeric constructs functionalized by reactive binding sites. The algorithm is based on the configurational bias…

Soft Condensed Matter · Physics 2015-06-23 Robin De Gernier , Tine Curk , Galina V. Dubacheva , Ralf P. Richter , Bortolo M. Mognetti

High-dimensional classification and feature selection tasks are ubiquitous with the recent advancement in data acquisition technology. In several application areas such as biology, genomics and proteomics, the data are often functional in…

Machine Learning · Statistics 2021-09-30 W Yu , S Wade , H D Bondell , L Azizi

Due to the automatic feature extraction procedure via multi-layer nonlinear transformations, the deep learning-based visual trackers have recently achieved great success in challenging scenarios for visual tracking purposes. Although many…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Seyed Mojtaba Marvasti-Zadeh , Hossein Ghanei-Yakhdan , Shohreh Kasaei

Machine learning provides a novel avenue for the study of experimental realizations of many-body systems, and has recently been proven successful in analyzing properties of experimental data of ultracold quantum gases. We here show that…

Computational Physics · Physics 2021-09-29 Corneel Casert , Kyle Mills , Tom Vieijra , Jan Ryckebusch , Isaac Tamblyn

The response-only model class selection capability of a novel deep convolutional neural network method is examined herein in a simple, yet effective, manner. Specifically, the responses from a unique degree of freedom along with their class…

Systems and Control · Electrical Eng. & Systems 2025-11-07 Marios Impraimakis

Microbial communities analysis is drawing growing attention due to the rapid development of high-throughput sequencing techniques nowadays. The observed data has the following typical characteristics: it is high-dimensional, compositional…

Methodology · Statistics 2020-04-30 Yong He , Pengfei Liu , Xinsheng Zhang , Wang Zhou

One of the most common analysis tasks in genomic research is to identify genes that are differentially expressed (DE) between experimental conditions. Empirical Bayes (EB) statistical tests using moderated genewise variances have been very…

Applications · Statistics 2016-07-28 Belinda Phipson , Stanley Lee , Ian J. Majewski , Warren S. Alexander , Gordon K. Smyth

Distribution shifts and minority subpopulations frequently undermine the reliability of deep neural networks trained using Empirical Risk Minimization (ERM). Distributionally Robust Optimization (DRO) addresses this by optimizing for the…

Machine Learning · Computer Science 2025-11-11 Aheer Sravon , Devdyuti Mazumder , Md. Ibrahim

Evolutionary algorithms, such as Differential Evolution, excel in solving real-parameter optimization challenges. However, the effectiveness of a single algorithm varies across different problem instances, necessitating considerable efforts…

Neural and Evolutionary Computing · Computer Science 2024-03-08 Hongshu Guo , Yining Ma , Zeyuan Ma , Jiacheng Chen , Xinglin Zhang , Zhiguang Cao , Jun Zhang , Yue-Jiao Gong

Over the past decades, statisticians and machine-learning researchers have developed literally thousands of new tools for the reduction of high-dimensional data in order to identify the variables most responsible for a particular trait.…

Machine Learning · Statistics 2012-05-31 Chamont Wang , Jana Gevertz , Chaur-Chin Chen , Leonardo Auslender

Data-efficient image classification is a challenging task that aims to solve image classification using small training data. Neural network-based deep learning methods are effective for image classification, but they typically require…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Ying Bi , Bing Xue , Mengjie Zhang

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Genome-Wide Association Studies (GWAS) face unique challenges in the era of big genomics data, particularly when dealing with ultra-high-dimensional datasets where the number of genetic features significantly exceeds the available samples.…

Genomics · Quantitative Biology 2023-12-27 Kexuan Li
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