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Using longitudinal study data, we dynamically model how aging affects homeostasis in both mice and humans. We operationalize homeostasis as a multivariate mean-reverting stochastic process. We hypothesize that biomarkers have stable…

Other Quantitative Biology · Quantitative Biology 2023-12-14 Glen Pridham , Andrew D. Rutenberg

Deep neural networks have shown remarkable performance across a wide range of vision-based tasks, particularly due to the availability of large-scale datasets for training and better architectures. However, data seen in the real world are…

Machine Learning · Computer Science 2018-11-26 Muhammad Usama , Dong Eui Chang

Understanding how multi-scale network structure influences circadian rhythms in the suprachiasmatic nucleus (SCN) is essential for uncovering the principles of rhythmic robustness and synchronization. Previous studies using synthetic SCN…

Physics and Society · Physics 2026-03-10 Youhao Zhuo , Yingpeng Liu , Jiao Wu , Kesheng Xu , Muhua Zheng

The reliability of autonomous systems depends on their robustness, i.e., their ability to meet their objectives under uncertainty. In this paper, we study spatiotemporal robustness of temporal logic specifications evaluated over…

Artificial Intelligence · Computer Science 2026-05-19 Oliver Schön , Lars Lindemann

The temporal activity of many biological systems, including neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. The mechanisms leading to this temporal heterogeneity are yet unknown. Here we show…

Disordered Systems and Neural Networks · Physics 2022-08-03 Merav Stern , Nicolae Istrate , Luca Mazzucato

Effective and Efficient spatio-temporal modeling is essential for action recognition. Existing methods suffer from the trade-off between model performance and model complexity. In this paper, we present a novel Spatio-Temporal Hybrid…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Xu Li , Jingwen Wang , Lin Ma , Kaihao Zhang , Fengzong Lian , Zhanhui Kang , Jinjun Wang

Time-fluctuating signals are ubiquitous and diverse in many physical, chemical, and biological systems, among which random telegraph signals (RTSs) refer to a series of instantaneous switching events between two discrete levels from…

Applied Physics · Physics 2022-06-02 Marcel Robitaille , HeeBong Yang , Lu Wang , Na Young Kim

Accurate temporal prediction is the bridge between comprehensive scene understanding and embodied artificial intelligence. However, predicting multiple fine-grained states of a scene at multiple temporal scales is difficult for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhitao Zeng , Guojian Yuan , Junyuan Mao , Yuxuan Wang , Xiaoshuang Jia , Yueming Jin

Neural activity exhibits a vast range of timescales that can be several fold larger than the membrane time constant of individual neurons. Two types of mechanisms have been proposed to explain this conundrum. One possibility is that large…

Neurons and Cognition · Quantitative Biology 2019-03-26 Manuel Beiran , Srdjan Ostojic

Spatiotemporal predictive learning, which predicts future frames through historical prior knowledge with the aid of deep learning, is widely used in many fields. Previous work essentially improves the model performance by widening or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Zhifeng Ma , Hao Zhang , Jie Liu

Many natural and engineered complex networks have intricate mesoscopic organization, e.g., the clustering of the constituent nodes into several communities or modules. Often, such modularity is manifested at several different hierarchical…

Physics and Society · Physics 2015-05-30 Sitabhra Sinha , Swarup Poria

Accurate forecasting of multivariate time series data remains a formidable challenge, particularly due to the growing complexity of temporal dependencies in real-world scenarios. While neural network-based models have achieved notable…

Machine Learning · Computer Science 2025-12-09 Andrey Savchenko , Oleg Kachan

In a manner similar to the molecular chaos that underlies the stable thermodynamics of gases, neuronal system may exhibit microscopic instability in individual neuronal dynamics while a macroscopic order of the entire population possibly…

Neurons and Cognition · Quantitative Biology 2015-06-23 Yuzuru Yamanaka , Shun-ichi Amari , Shigeru Shinomoto

Artificial neural networks and computational neuroscience models have made tremendous progress, allowing computers to achieve impressive results in artificial intelligence (AI) applications, such as image recognition, natural language…

Neural and Evolutionary Computing · Computer Science 2019-11-05 Giacomo Indiveri , Yulia Sandamirskaya

Hierarchical structures exist in both linguistics and Natural Language Processing (NLP) tasks. How to design RNNs to learn hierarchical representations of natural languages remains a long-standing challenge. In this paper, we define two…

Computation and Language · Computer Science 2021-06-07 Zhaoxin Luo , Michael Zhu

Spiking Neural Networks (SNNs), models inspired by neural mechanisms in the brain, allow for energy-efficient implementation on neuromorphic hardware. However, SNNs trained with current direct training approaches are constrained to a…

Machine Learning · Computer Science 2025-03-25 Kangrui Du , Yuhang Wu , Shikuang Deng , Shi Gu

Although deep feedforward neural networks share some characteristics with the primate visual system, a key distinction is their dynamics. Deep nets typically operate in serial stages wherein each layer completes its computation before…

Machine Learning · Computer Science 2021-11-03 Michael L. Iuzzolino , Michael C. Mozer , Samy Bengio

Spatio-temporal data are ubiquitous in the agricultural, ecological, and environmental sciences, and their study is important for understanding and predicting a wide variety of processes. One of the difficulties with modeling spatial…

Machine Learning · Statistics 2019-02-25 Christopher K. Wikle

In real-world networks the interactions between network elements are inherently time-delayed. These time-delays can not only slow the network but can have a destabilizing effect on the network's dynamics leading to poor performance. The…

Optimization and Control · Mathematics 2024-09-23 David Reber , Benjamin Webb

Networks of neural mass nodes with delayed interactions are increasingly being used as models for large-scale brain activity. To complement the growing number of computational studies of such networks, it is timely to develop new…

Dynamical Systems · Mathematics 2025-09-29 S Coombes , H G E Meijer