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Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

Neurons and Cognition · Quantitative Biology 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Human brain networks can be characterized at different temporal or spatial scales given by the age of the subject or the spatial resolution of the neuroimaging method. Integration of data across scales can only be successful if the combined…

Attention Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition; however, its neurobiological diagnosis remains challenging due to the lack of reliable imaging-based biomarkers, particularly anatomical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Qurat Ul Ain , Alptekin Temizel , Soyiba Jawed

Traditional neuroimage analysis pipelines involve computationally intensive, time-consuming optimization steps, and thus, do not scale well to large cohort studies with thousands or tens of thousands of individuals. In this work we propose…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Leonie Henschel , Sailesh Conjeti , Santiago Estrada , Kersten Diers , Bruce Fischl , Martin Reuter

The quantitative characterization of the microstructure of random heterogeneous media in $d$-dimensional Euclidean space $\mathbb{R}^d$ via a variety of $n$-point correlation functions is of great importance, since the respective infinite…

Soft Condensed Matter · Physics 2018-08-07 Zheng Ma , Salvatore Torquato

Skull stripping for brain MR images is a basic segmentation task. Although many methods have been proposed, most of them focused mainly on the adult MR images. Skull stripping for infant MR images is more challenging due to the small size…

Computer Vision and Pattern Recognition · Computer Science 2019-10-11 Qian Zhang , Li Wang , Xiaopeng Zong , Weili Lin , Gang Li , Dinggang Shen

Bone age is an important measure for assessing the skeletal and biological maturity of children. Delayed or increased bone age is a serious concern for pediatricians, and needs to be accurately assessed in a bid to determine whether bone…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Ibrahim Salim , A. Ben Hamza

Hypoxic-Ischemic Encephalopathy (HIE) affects 1 to 5 out of every 1,000 newborns, with 30% to 50% of cases resulting in adverse neurocognitive outcomes. However, these outcomes can only be reliably assessed as early as age 2. Therefore,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Rina Bao , Sheng He , Ellen Grant , Yangming Ou

Deciphering brain network topology can enhance the depth of neuroscientific knowledge and facilitate the development of neural engineering methods. Effective connectivity, a measure of brain network dynamics, is particularly useful for…

Neurons and Cognition · Quantitative Biology 2023-12-01 Chun-Hsiang Chuang , Shao-Xun Fang , Chih-Sheng Huang , Weiping Ding

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years.…

Machine Learning · Computer Science 2020-03-13 Tiago Azevedo , Luca Passamonti , Pietro Liò , Nicola Toschi

Background: Brain maturation and aging involve significant microstructural changes, resulting in functional and cognitive alterations. Quantitative MRI (qMRI) can measure this evolution, distinguishing the physiological effects of normal…

This study investigated age-related changes in functional connectivity using resting-state fMRI and explored the efficacy of traditional deep learning for classifying brain developmental stages (BDS). Functional connectivity was assessed…

Neurons and Cognition · Quantitative Biology 2025-03-28 Prerna Singh , Kuldeep Singh Yadav , Lalan Kumar , Tapan Kumar Gandhi

A novel unsupervised deep learning method is developed to identify individual-specific large scale brain functional networks (FNs) from resting-state fMRI (rsfMRI) in an end-to-end learning fashion. Our method leverages deep Encoder-Decoder…

Computer Vision and Pattern Recognition · Computer Science 2020-12-14 Hongming Li , Yong Fan

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Mirza Ahsan Ullah , Tehseen Zia

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

Machine Learning · Computer Science 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

A large number of surface-based analyses on brain imaging data adopt some specific brain atlases to better assess structural and functional changes in one or more brain regions. In these analyses, it is necessary to obtain an anatomically…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Wen Zhang , Yalin Wang