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Related papers: MedMO: Grounding and Understanding Multimodal Larg…

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In recent years, Multimodal Large Language Models (MLLM) have achieved notable advancements, demonstrating the feasibility of developing an intelligent biomedical assistant. However, current biomedical MLLMs predominantly focus on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Xiaoshuang Huang , Lingdong Shen , Jia Liu , Fangxin Shang , Hongxiang Li , Haifeng Huang , Yehui Yang

Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Songtao Jiang , Tuo Zheng , Yan Zhang , Yeying Jin , Li Yuan , Zuozhu Liu

Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

Multimodal Large Language Models (MLLMs) inherit the superior text understanding capabilities of LLMs and extend these capabilities to multimodal scenarios. These models achieve excellent results in the general domain of multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinlong He , Pengfei Li , Gang Liu , Shenjun Zhong

Clinical decision-making routinely demands reasoning over heterogeneous data, yet existing multimodal language models (MLLMs) remain largely vision-centric and fail to generalize across clinical specialties. To bridge this gap, we introduce…

Machine Learning · Computer Science 2025-10-23 Wei Dai , Peilin Chen , Chanakya Ekbote , Paul Pu Liang

Medical image grounding aims to align natural language phrases with specific regions in medical images, serving as a foundational task for intelligent diagnosis, visual question answering (VQA), and automated report generation (MRG).…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Ziye Deng , Ruihan He , Jiaxiang Liu , Yuan Wang , Zijie Meng , Songtao Jiang , Yong Xie , Zuozhu Liu

Medicine, by its nature, is a multifaceted domain that requires the synthesis of information across various modalities. Medical generative vision-language models (VLMs) make a first step in this direction and promise many exciting clinical…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Michael Moor , Qian Huang , Shirley Wu , Michihiro Yasunaga , Cyril Zakka , Yash Dalmia , Eduardo Pontes Reis , Pranav Rajpurkar , Jure Leskovec

Generalist multimodal large language models (MLLMs) have achieved impressive performance across a wide range of vision-language tasks. However, their performance on medical tasks, particularly in zero-shot settings where generalization is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guimeng Liu , Tianze Yu , Somayeh Ebrahimkhani , Lin Zhi Zheng Shawn , Kok Pin Ng , Ngai-Man Cheung

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

Recent advances in multimodal large language models (MLLMs) have significantly improved medical AI, enabling it to unify the understanding of visual and textual information. However, as medical knowledge continues to evolve, it is critical…

Artificial Intelligence · Computer Science 2025-08-08 Dexuan Xu , Jieyi Wang , Zhongyan Chai , Yongzhi Cao , Hanpin Wang , Huamin Zhang , Yu Huang

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

State-of-the-art medical multi-modal LLMs (med-MLLMs), such as LLaVA-Med and BioMedGPT, primarily depend on scaling model size and data volume, with training driven largely by autoregressive objectives. However, we reveal that this approach…

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Visual grounding is essential for precise perception and reasoning in multimodal large language models (MLLMs), especially in medical imaging domains. While existing medical visual grounding benchmarks primarily focus on single-image…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Jingkun Yue , Siqi Zhang , Zinan Jia , Huihuan Xu , Zongbo Han , Xiaohong Liu , Guangyu Wang

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Artificial Intelligence · Computer Science 2025-08-06 Mahtab Bigverdi , Wisdom Ikezogwo , Kevin Zhang , Hyewon Jeong , Mingyu Lu , Sungjae Cho , Linda Shapiro , Ranjay Krishna

Multimodal Large Language Models (MLLMs) have demonstrated impressive progress in single-image grounding and general multi-image understanding. Recently, some methods begin to address multi-image grounding. However, they are constrained by…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Shurong Zheng , Yousong Zhu , Hongyin Zhao , Fan Yang , Yufei Zhan , Ming Tang , Jinqiao Wang

Recent advances in reinforcement learning with verifiable, rule-based rewards have greatly enhanced the reasoning capabilities and out-of-distribution generalization of VLMs/LLMs, obviating the need for manually crafted reasoning chains.…

Artificial Intelligence · Computer Science 2025-05-27 Shaohao Rui , Kaitao Chen , Weijie Ma , Xiaosong Wang

Recently a number of studies demonstrated impressive performance on diverse vision-language multi-modal tasks such as image captioning and visual question answering by extending the BERT architecture with multi-modal pre-training…

Computer Vision and Pattern Recognition · Computer Science 2022-09-22 Jong Hak Moon , Hyungyung Lee , Woncheol Shin , Young-Hak Kim , Edward Choi

Currently, medical vision language models are widely used in medical vision question answering tasks. However, existing models are confronted with two issues: for input, the model only relies on text instructions and lacks direct…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Yanyuan Chen , Dexuan Xu , Yu Huang , Songkun Zhan , Hanpin Wang , Dongxue Chen , Xueping Wang , Meikang Qiu , Hang Li
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