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Objective: Closed-loop deep brain stimulation (DBS) may improve current clinical DBS treatment for neurological movement disorders, but control algorithms may perform differently across patients. New metrics are needed for comparing and…

Neurons and Cognition · Quantitative Biology 2016-05-31 Jeffrey Herron , Anca Velisar , Mahsa Malekmohammadi , Helen Bronte-Stewart , Howard Jay Chizeck

Working memory (WM) is a mechanism that temporarily stores and manipulates information in service of behavioral goals and is a highly dynamic process. Previous studies have considered decoding WM load using EEG but have not investigated the…

Neurons and Cognition · Quantitative Biology 2019-10-15 Samuel Goldstein , Zhenhong Hu , Mingzhou Ding

Robot-assisted Transcranial Magnetic Stimulation (Robo-TMS) is an image-guided robotic intervention that enhances the accuracy and reproducibility of conventional Transcranial Magnetic Stimulation (TMS), a widely used non-invasive brain…

Robotics · Computer Science 2026-04-29 Wenzhi Bai , Yituo Guo , Bhaskar Basu , Andrew Weightman , Zhenhong Li

Emotion recognition based on Electroencephalography (EEG) has gained significant attention and diversified development in fields such as neural signal processing and affective computing. However, the unique brain anatomy of individuals…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Yihang Dong , Xuhang Chen , Yanyan Shen , Michael Kwok-Po Ng , Tao Qian , Shuqiang Wang

During daily activities, humans use their hands to grasp surrounding objects and perceive sensory information which are also employed for perceptual and motor goals. Multiple cortical brain regions are known to be responsible for sensory…

Signal Processing · Electrical Eng. & Systems 2021-03-08 Ozan Ozdenizci , Safaa Eldeeb , Andac Demir , Deniz Erdogmus , Murat Akcakaya

Transcranial magnetic stimulation (TMS) is widely used for understanding brain function in neurologically intact subjects and for the treatment of various disorders. However, the precise neurophysiological effects of TMS at the site of…

Neurons and Cognition · Quantitative Biology 2021-10-27 Farshad Rafiei , Dobromir Rahnev

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Medical Physics · Physics 2023-12-27 Max Koehler , Stefan Goetz

EEG-based analysis of pain perception, enhanced by machine learning, reveals how the brain encodes pain by identifying neural patterns evoked by noxious stimulation. However, a major challenge that remains is the generalization of machine…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Mathis Rezzouk , Fabrice Gagnon , Alyson Champagne , Mathieu Roy , Philippe Albouy , Michel-Pierre Coll , Cem Subakan

Electrical muscle stimulation (EMS) can support physical-assistance (e.g., shaking a spray-can before painting). However, EMS-assistance is highly-specialized because it is (1) fixed (e.g., one program for shaking spray-cans, another for…

Human-Computer Interaction · Computer Science 2026-02-12 Yun Ho , Romain Nith , Peili Jiang , Steven He , Bruno Felalaga , Shan-Yuan Teng , Rhea Seeralan , Pedro Lopes

Neurophysiological time series recordings like the electroencephalogram (EEG) or local field potentials are obtained from multiple sensors. They can be decoded by machine learning models in order to estimate the ongoing brain state of a…

Signal Processing · Electrical Eng. & Systems 2023-04-14 Pierre Guetschel , Théodore Papadopoulo , Michael Tangermann

MEG and EEG are noninvasive functional neuroimaging techniques that provide recordings of brain activity with high temporal resolution, and thus provide a unique window to study fast time-scale neural dynamics in humans. However, the…

Applications · Statistics 2015-11-13 Camilo Lamus , Matti S. Hamalainen , Emery N. Brown , Patrick L. Purdon

Brain activity following stimulus presentation and during resting state are often the result of highly coordinated responses of large numbers of neurons both locally and globally. Coordinated activity of neurons can give rise to…

Applications · Statistics 2015-07-20 Carolina Euan , Hernando Ombao , Joaquin Ortega

Analyzing and reconstructing visual stimuli from brain signals effectively advances the understanding of human visual system. However, the EEG signals are complex and contain significant noise. This leads to substantial limitations in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Honghao Fu , Zhiqi Shen , Jing Jih Chin , Hao Wang

Developments in Brain Computer Interfaces (BCIs) are empowering those with severe physical afflictions through their use in assistive systems. Common methods of achieving this is via Motor Imagery (MI), which maps brain signals to code for…

Signal Processing · Electrical Eng. & Systems 2020-05-28 Abdul Moeed

In several diagnosis and therapy procedures based on electrostimulation effect, the internal physical quantity related to the stimulation is the induced electric field. To estimate the induced electric field in an individual human model,…

Medical Physics · Physics 2021-02-03 Essam A. Rashed , Jose Gomez-Tames , Akimasa Hirata

In recent years, emotional Text-to-Speech (TTS) synthesis and emphasis-controllable speech synthesis have advanced significantly. However, their interaction remains underexplored. We propose Emphasis Meets Emotion TTS (EME-TTS), a novel…

Sound · Computer Science 2025-07-17 Haoxun Li , Leyuan Qu , Jiaxi Hu , Taihao Li

Machine learning (ML) methods have the potential to automate clinical EEG analysis. They can be categorized into feature-based (with handcrafted features), and end-to-end approaches (with learned features). Previous studies on EEG pathology…

Electroencephalography (EEG) signals reflect activities on certain brain areas. Effective classification of time-varying EEG signals is still challenging. First, EEG signal processing and feature engineering are time-consuming and highly…

Human-Computer Interaction · Computer Science 2019-08-27 Xiang Zhang , Lina Yao , Xianzhi Wang , Wenjie Zhang , Shuai Zhang , Yunhao Liu

Motivated behaviour relies on the brain's capacity to evaluate effort and reward. Dysregulation within these processes contributes to a spectrum of conditions, from hyperactivity in attention-deficit/hyperactivity disorder (ADHD) to…

Neurons and Cognition · Quantitative Biology 2026-04-20 Nam Trinh

Essential Tremor is the most common neurological movement disorder. This progressive disease causes uncontrollable rhythmic motions -most often affecting the patient's dominant upper extremity- that occur during volitional movement and make…

Neurons and Cognition · Quantitative Biology 2017-06-02 Jeffrey A. Herron , Margaret C. Thompson , Timothy Brown , Howard J. Chizeck , Jeffrey G. Ojemann , Andrew L. Ko
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