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The remarkable capabilities of Large Language Model (LLM)-driven agents have enabled sophisticated systems to tackle complex, multi-step tasks, but their escalating costs threaten scalability and accessibility. This work presents the first…

Designing high-performance system heuristics is a creative, iterative process requiring experts to form hypotheses and execute multi-step conceptual shifts. While Large Language Models (LLMs) show promise in automating this loop, they…

Artificial Intelligence · Computer Science 2026-03-24 Pantea Karimi , Kimia Noorbakhsh , Mohammad Alizadeh , Hari Balakrishnan

Agentic systems have transformed how Large Language Models (LLMs) can be leveraged to create autonomous systems with goal-directed behaviors, consisting of multi-step planning and the ability to interact with different environments. These…

Artificial Intelligence · Computer Science 2026-01-27 Judy Zhu , Dhari Gandhi , Himanshu Joshi , Ahmad Rezaie Mianroodi , Sedef Akinli Kocak , Dhanesh Ramachandran

Multimodal Large Language Models (MLLMs) are undergoing rapid progress and represent the frontier of AI development. However, their training and inference efficiency have emerged as a core bottleneck in making MLLMs more accessible and…

Large Language Models (LLMs) have shown tremendous potential as agents, excelling at tasks that require multiple rounds of reasoning and interactions. Rejection Sampling Fine-Tuning (RFT) has emerged as an effective method for finetuning…

Artificial Intelligence · Computer Science 2025-04-22 Li-Cheng Lan , Andrew Bai , Minhao Cheng , Cho-Jui Hsieh , Tianyi Zhou

Open-sourced Large Language Models (LLMs) have achieved great success in various NLP tasks, however, they are still far inferior to API-based models when acting as agents. How to integrate agent ability into general LLMs becomes a crucial…

Computation and Language · Computer Science 2024-03-20 Zehui Chen , Kuikun Liu , Qiuchen Wang , Wenwei Zhang , Jiangning Liu , Dahua Lin , Kai Chen , Feng Zhao

Large Language Model (LLM)-based agents that plan, use tools and act has begun to shape healthcare and medicine. Reported studies demonstrate competence on various tasks ranging from EHR analysis and differential diagnosis to treatment…

Artificial Intelligence · Computer Science 2026-02-05 Shubham Vatsal , Harsh Dubey , Aditi Singh

With the rapid development of LLM-based agents, there is a growing trend to incorporate agent-specific data into the pre-training stage of LLMs, aiming to better align LLMs with real-world autonomous task execution. However, current…

Artificial Intelligence · Computer Science 2025-10-29 Jiarui Qin , Yunjia Xi , Junjie Huang , Renting Rui , Di Yin , Weiwen Liu , Yong Yu , Weinan Zhang , Xing Sun

Recent studies have uncovered the potential of Large Language Models (LLMs) in addressing complex sequential decision-making tasks through the provision of high-level instructions. However, LLM-based agents lack specialization in tackling…

Artificial Intelligence · Computer Science 2024-05-28 Zihao Zhou , Bin Hu , Chenyang Zhao , Pu Zhang , Bin Liu

This paper studies the next major bottleneck in agentic AI as system scaling, not only model scaling: the design of auditable, persistent, modular, and verifiable architectures around foundation models. We refer to this shift as scaling the…

Artificial Intelligence · Computer Science 2026-05-26 Shangding Gu

Reasoning is a fundamental cognitive process underlying inference, problem-solving, and decision-making. While large language models (LLMs) demonstrate strong reasoning capabilities in closed-world settings, they struggle in open-ended and…

Multi-agent systems built on Large Language Models (LLMs) show exceptional promise for complex collaborative problem-solving, yet they face fundamental challenges stemming from context window limitations that impair memory consistency, role…

Artificial Intelligence · Computer Science 2026-01-13 Sizhe Yuen , Francisco Gomez Medina , Ting Su , Yali Du , Adam J. Sobey

Agent-based modeling and simulation has evolved as a powerful tool for modeling complex systems, offering insights into emergent behaviors and interactions among diverse agents. Integrating large language models into agent-based modeling…

Artificial Intelligence · Computer Science 2023-12-20 Chen Gao , Xiaochong Lan , Nian Li , Yuan Yuan , Jingtao Ding , Zhilun Zhou , Fengli Xu , Yong Li

A growing body of work explores how Large Language Models (LLMs) can be embedded in trading systems as agents that perceive market information, retrieve context, reason about decisions, emit tradable actions, and adapt under market…

Artificial Intelligence · Computer Science 2026-05-20 Yihan Xia , Panpan You , Taotao Wang , Fang Liu , Han Qi , Xiaoxiao Wu , Shengli Zhang

As the strength of Large Language Models (LLMs) has grown over recent years, so too has interest in their use as the underlying models for autonomous agents. Although LLMs demonstrate emergent abilities and broad expertise across natural…

Artificial Intelligence · Computer Science 2024-12-06 Chris Sypherd , Vaishak Belle

Agentic systems for drug discovery have demonstrated autonomous synthesis planning, literature mining, and molecular design. We ask how well they generalize. Evaluating six frameworks against 15 task classes drawn from peptide therapeutics,…

Quantitative Methods · Quantitative Biology 2026-02-12 Edward Wijaya

Large Language Models (LLMs) are increasingly applied to software engineering (SE), yet their potential for autonomous, role-oriented collaboration remains largely underexplored. Understanding how multiple LLM-based agents coordinate,…

Large language model (LLM)-based agents that reason, plan, and act through tools, memory, and structured interaction are emerging as a promising paradigm for automating complex workflows. Recent systems such as OpenClaw and Claude Code…

Information Retrieval · Computer Science 2026-05-27 Yingli Zhou , Wang Shu , Yaodong Su , Wenchuan Du , Yixiang Fang , Xuemin Lin

The integration of Large Language Model (LLM) agents is transforming recommender systems from simple query-item matching towards deeply personalized and interactive recommendations. Reinforcement Learning (RL) provides an essential…

Memory emerges as the core module in the Large Language Model (LLM)-based agents for long-horizon complex tasks (e.g., multi-turn dialogue, game playing, scientific discovery), where memory can enable knowledge accumulation, iterative…

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