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The rapid advancement in capabilities of large language models (LLMs) raises a pivotal question: How can LLMs accelerate scientific discovery? This work tackles the crucial first stage of research, generating novel hypotheses. While recent…

Artificial Intelligence · Computer Science 2025-05-27 Aniketh Garikaparthi , Manasi Patwardhan , Lovekesh Vig , Arman Cohan

Large language models (LLMs) have been extensively studied for their abilities to generate convincing natural language sequences, however their utility for quantitative information retrieval is less well understood. Here we explore the…

Early exiting has recently emerged as a promising technique for accelerating large language models (LLMs) by effectively reducing the hardware computation and memory access. In this paper, we present SpecEE, a fast LLM inference engine with…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-15 Jiaming Xu , Jiayi Pan , Yongkang Zhou , Siming Chen , Jinhao Li , Yaoxiu Lian , Junyi Wu , Guohao Dai

Data-driven social science research is inherently slow, relying on iterative cycles of observation, hypothesis generation, and experimental validation. While recent data-driven methods promise to accelerate parts of this process, they…

Reinforcement learning with verifiable rewards (RLVR) for Large Reasoning Models hinges on baseline estimation for variance reduction, but existing approaches pay a heavy price: PPO requires a policy-model scale critic, while GRPO needs…

Machine Learning · Computer Science 2026-05-12 Yunho Choi , Jongwon Lim , Woojin Ahn , Minjae Oh , Jeonghoon Shim , Yohan Jo

The optimization of composition and processing to obtain materials that exhibit desirable characteristics has historically relied on a combination of scientist intuition, trial and error, and luck. We propose a methodology that can…

Machine Learning · Statistics 2017-07-20 Julia Ling , Max Hutchinson , Erin Antono , Sean Paradiso , Bryce Meredig

Large Language Models (LLMs) have shown significant advances in text generation but often lack the reliability needed for autonomous deployment in high-stakes domains like healthcare, law, and finance. Existing approaches rely on external…

Artificial Intelligence · Computer Science 2024-11-12 Ninad Naik

Key Information Extraction (KIE) from visually-rich documents (VrDs) is a critical task, for which recent Large Language Models (LLMs) and Multi-Modal Large Language Models (MLLMs) have demonstrated strong potential. However, their reliance…

Computation and Language · Computer Science 2026-01-28 Xinzhong Wang , Ya Guo , Jing Li , Huan Chen , Yi Tu , Yijie Hong , Gongshen Liu , Huijia Zhu

Reinforcement learning with verifiable rewards (RLVR) has improved the reasoning ability of large language models, yet training remains costly because many rollouts contribute little to optimization, considering the amount of computation…

Machine Learning · Computer Science 2026-02-20 Yan Sun , Jia Guo , Stanley Kok , Zihao Wang , Zujie Wen , Zhiqiang Zhang

Medical Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities across diverse healthcare tasks. However, current post-training strategies, such as supervised fine-tuning and reinforcement learning, heavily depend…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Dunyuan Xu , Xikai Yang , Juzheng Miao , Yaoqian Li , Jinpeng Li , Pheng-Ann Heng

Large Language Models (LLMs) demonstrate strong few-shot generalization through in-context learning, yet their reasoning in dynamic and stochastic environments remains opaque. Prior studies mainly focus on static tasks and overlook the…

Artificial Intelligence · Computer Science 2025-12-23 Jensen Zhang , Jing Yang , Keze Wang

Efficient exploration remains a central challenge in reinforcement learning, serving as a useful pretraining objective for data collection, particularly when an external reward function is unavailable. A principled formulation of the…

Machine Learning · Computer Science 2026-03-16 Jacob Adamczyk , Adam Kamoski , Rahul V. Kulkarni

Retrieval-augmented in-context learning has emerged as a powerful approach for addressing knowledge-intensive tasks using frozen language models (LM) and retrieval models (RM). Existing work has combined these in simple "retrieve-then-read"…

Computation and Language · Computer Science 2023-01-24 Omar Khattab , Keshav Santhanam , Xiang Lisa Li , David Hall , Percy Liang , Christopher Potts , Matei Zaharia

We present BEEP (Biomedical Evidence-Enhanced Predictions), a novel approach for clinical outcome prediction that retrieves patient-specific medical literature and incorporates it into predictive models. Based on each individual patient's…

Computation and Language · Computer Science 2022-11-17 Aakanksha Naik , Sravanthi Parasa , Sergey Feldman , Lucy Lu Wang , Tom Hope

Bayesian optimization is normally performed within fixed variable bounds. In cases like hyperparameter tuning for machine learning algorithms, setting the variable bounds is not trivial. It is hard to guarantee that any fixed bounds will…

Optimization and Control · Mathematics 2020-01-15 Wei Chen , Mark Fuge

Many real-world optimization problems are guided by complex, subjective preferences that are difficult to express as explicit closed-form objectives. In response, we introduce Language-in-the-Loop Optimization (LILO), a Bayesian…

Machine Learning · Computer Science 2026-05-12 Katarzyna Kobalczyk , Zhiyuan Jerry Lin , Benjamin Letham , Zhuokai Zhao , Maximilian Balandat , Eytan Bakshy

Scientific discovery is a cumulative process and requires new ideas to be situated within an ever-expanding landscape of existing knowledge. An emerging and critical challenge is how to identify conceptually relevant prior work from rapidly…

Information Retrieval · Computer Science 2026-01-15 Yuexi Shen , Minqian Liu , Dawei Zhou , Lifu Huang

The rapid advancement of Large Language Models (LLMs) has outpaced traditional evaluation methods. Static benchmarks fail to capture the depth and breadth of LLM capabilities and eventually become obsolete, while most dynamic approaches…

Artificial Intelligence · Computer Science 2025-04-11 Vahid Majdinasab , Amin Nikanjam , Foutse Khomh

A framework to boost the efficiency of Bayesian inference in probabilistic programs is introduced by embedding a sampler inside a variational posterior approximation. We call it the refined variational approximation. Its strength lies both…

Machine Learning · Computer Science 2020-02-25 Victor Gallego , David Rios Insua

Large language models (LLMs) have shown promising abilities as cost-effective and reference-free evaluators for assessing language generation quality. In particular, pairwise LLM evaluators, which compare two generated texts and determine…

Computation and Language · Computer Science 2024-10-15 Han Zhou , Xingchen Wan , Yinhong Liu , Nigel Collier , Ivan Vulić , Anna Korhonen
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