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Medical vision-language pretraining (VLP) that leverages naturally-paired medical image-report data is crucial for medical image analysis. However, existing methods struggle to accurately characterize associations between images and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Xinjie Liang , Xiangyu Li , Fanding Li , Jie Jiang , Qing Dong , Wei Wang , Kuanquan Wang , Suyu Dong , Gongning Luo , Shuo Li

Medical vision-and-language pre-training (Med-VLP) has received considerable attention owing to its applicability to extracting generic vision-and-language representations from medical images and texts. Most existing methods mainly contain…

Computation and Language · Computer Science 2022-09-16 Zhihong Chen , Guanbin Li , Xiang Wan

Automatic phenotype concept recognition from unstructured text remains a challenging task in biomedical text mining research. Previous works that address the task typically use dictionary-based matching methods, which can achieve high…

Computation and Language · Computer Science 2021-01-26 Ling Luo , Shankai Yan , Po-Ting Lai , Daniel Veltri , Andrew Oler , Sandhya Xirasagar , Rajarshi Ghosh , Morgan Similuk , Peter N. Robinson , Zhiyong Lu

Vision-and-language pretraining (VLP) in the medical field utilizes contrastive learning on image-text pairs to achieve effective transfer across tasks. Yet, current VLP approaches with the masked modeling strategy face two challenges when…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Biao Wu , Yutong Xie , Zeyu Zhang , Minh Hieu Phan , Qi Chen , Ling Chen , Qi Wu

Vision-Language Models (VLMs) trained via contrastive learning have achieved notable success in natural image tasks. However, their application in the medical domain remains limited due to the scarcity of openly accessible, large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Muhammad Uzair Khattak , Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

Fine-grained entity typing (FET), which assigns entities in text with context-sensitive, fine-grained semantic types, is a basic but important task for knowledge extraction from unstructured text. FET has been studied extensively in natural…

Computation and Language · Computer Science 2024-06-12 Tanay Komarlu , Minhao Jiang , Xuan Wang , Jiawei Han

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Despite the large number of patients in Electronic Health Records (EHRs), the subset of usable data for modeling outcomes of specific phenotypes are often imbalanced and of modest size. This can be attributed to the uneven coverage of…

Machine Learning · Computer Science 2021-03-25 Mohamed Ghalwash , Zijun Yao , Prithwish Chakraborty , James Codella , Daby Sow

Recent years have witnessed the fast development of large-scale pre-training frameworks that can extract multi-modal representations in a unified form and achieve promising performances when transferred to downstream tasks. Nevertheless,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Xuran Pan , Tianzhu Ye , Dongchen Han , Shiji Song , Gao Huang

In this paper, we focus on monolithic Multimodal Large Language Models (MLLMs) that integrate visual encoding and language decoding into a single LLM. In particular, we identify that existing pre-training strategies for monolithic MLLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Gen Luo , Xue Yang , Wenhan Dou , Zhaokai Wang , Jiawen Liu , Jifeng Dai , Yu Qiao , Xizhou Zhu

Early detection of eye diseases like glaucoma, macular degeneration, and diabetic retinopathy is crucial for preventing vision loss. While artificial intelligence (AI) foundation models hold significant promise for addressing these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Danli Shi , Weiyi Zhang , Jiancheng Yang , Siyu Huang , Xiaolan Chen , Mayinuer Yusufu , Kai Jin , Shan Lin , Shunming Liu , Qing Zhang , Mingguang He

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Recent advancements in vision-language models (VLMs), such as CLIP, have demonstrated substantial success in self-supervised representation learning for vision tasks. However, effectively adapting VLMs to downstream applications remains…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Contrastive Language-Image Pretraining (CLIP) has demonstrated strong generalization for vision-language tasks in computer vision and medical domains, yet its text encoder accepts only up to 77 tokens, which limits its ability to represent…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Xiaoyang Wei , Camille Kurtz , Florence Cloppet

Integrating functional magnetic resonance imaging (fMRI) connectivity data with phenotypic textual descriptors (e.g., disease label, demographic data) holds significant potential to advance our understanding of neurological conditions.…

Machine Learning · Computer Science 2025-03-31 Yanting Yang , Xiaoxiao Li

Vision-language pretraining (VLP) has emerged as a powerful paradigm in medical image analysis, enabling representation learning from large-scale image-text pairs without relying on expensive manual annotations. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Xieji Li , Siyuan Yan , Yingsheng Liu , H. Peter Soyer , Monika Janda , Victoria Mar , Zongyuan Ge

Vision-Language Pretraining (VLP) has achieved remarkable success across various downstream tasks, but such gains are largely driven by scaling up on training data. Yet, literature methods treat image-text pairs as isolated training…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Wenbo Lu

The scarcity of annotated data has sparked significant interest in unsupervised pre-training methods that leverage medical reports as auxiliary signals for medical visual representation learning. However, existing research overlooks the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Zhe Li , Laurence T. Yang , Bocheng Ren , Xin Nie , Zhangyang Gao , Cheng Tan , Stan Z. Li

We introduce Quantized Language-Image Pretraining (QLIP), a visual tokenization method that combines state-of-the-art reconstruction quality with state-of-the-art zero-shot image understanding. QLIP trains a…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Yue Zhao , Fuzhao Xue , Scott Reed , Linxi Fan , Yuke Zhu , Jan Kautz , Zhiding Yu , Philipp Krähenbühl , De-An Huang
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