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Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

On-policy reinforcement learning methods like GRPO suffer from mode collapse: they exhibit reduced solution diversity, concentrating probability mass on a single solution once discovered and ceasing exploration of alternative strategies. We…

Artificial Intelligence · Computer Science 2026-05-20 Xiaozhe Li , Yang Li , Xinyu Fang , Shengyuan Ding , Peiji Li , Yongkang Chen , Yichuan Ma , Tianyi Lyu , Linyang Li , Dahua Lin , Qipeng Guo , Qingwen Liu , Kai Chen

GRPO is a standard approach to endowing pretrained LLMs with reasoning capabilities. It estimates the advantage of an outcome from a group of $K$ outcomes, and promotes those with positive advantages inside a trust region. Since GRPO…

Machine Learning · Computer Science 2026-02-02 Wenzheng Zhang , Karl Stratos

Trust region policy optimization (TRPO) is a popular and empirically successful policy search algorithm in Reinforcement Learning (RL) in which a surrogate problem, that restricts consecutive policies to be 'close' to one another, is…

Machine Learning · Computer Science 2019-12-13 Lior Shani , Yonathan Efroni , Shie Mannor

Group-based reinforcement learning methods, like Group Relative Policy Optimization (GRPO), are widely used nowadays to post-train large language models. Despite their empirical success, they exhibit structural mismatches between reward…

Machine Learning · Computer Science 2026-01-09 Aleksandar Fontana , Marco Simoni , Giulio Rossolini , Andrea Saracino , Paolo Mori

LoRA achieves remarkable resource efficiency and comparable performance when adapting LLMs for specific tasks. Since ChatGPT demonstrated superior performance on various tasks, there has been a growing desire to adapt one model for all…

Machine Learning · Computer Science 2023-11-21 Yiming Wang , Yu Lin , Xiaodong Zeng , Guannan Zhang

Proximal Policy Optimization (PPO) is central to aligning Large Language Models (LLMs) in reasoning tasks with verifiable rewards. However, standard token-level PPO struggles in this setting due to the instability of temporal credit…

Artificial Intelligence · Computer Science 2026-04-13 Tianyi Wang , Yixia Li , Long Li , Yibiao Chen , Shaohan Huang , Yun Chen , Peng Li , Yang Liu , Guanhua Chen

Multimodal Large Language Models (MLLMs) are powerful at integrating diverse data, but they often struggle with complex reasoning. While Reinforcement learning (RL) can boost reasoning in LLMs, applying it to MLLMs is tricky. Common issues…

Machine Learning · Computer Science 2025-06-30 Minjie Hong , Zirun Guo , Yan Xia , Zehan Wang , Ziang Zhang , Tao Jin , Zhou Zhao

Reinforcement learning (RL) training is inherently unstable due to factors such as moving targets and high gradient variance. Reinforcement Learning from Human Feedback (RLHF) and Reinforcement Learning from AI Feedback (RLAIF) can…

Machine Learning · Computer Science 2025-06-24 Ju-Seung Byun , Andrew Perrault

Most of the traditional Applicant Tracking Systems (ATS) depend on strict matching using keywords, where candidates that are highly qualified are many times disqualified because of minor semantic differences. In this article, the two-stage…

Machine Learning · Computer Science 2026-01-21 Shreyansh Jain , Madhav Singhvi , Shreya Rahul Jain , Pranav S , Dishaa Lokesh , Naren Chittibabu , Akash Anandhan

Effective information seeking in multi-turn medical dialogues is critical for accurate diagnosis, especially when dealing with incomplete information. Aligning Large Language Models (LLMs) for these interactive scenarios is challenging due…

Machine Learning · Computer Science 2026-03-04 Ruike Cao , Shaojie Bai , Fugen Yao , Liang Dong , Jian Xu , Li Xiao

Modern meta-reinforcement learning (Meta-RL) methods are mainly developed based on model-agnostic meta-learning, which performs policy gradient steps across tasks to maximize policy performance. However, the gradient conflict problem is…

Artificial Intelligence · Computer Science 2022-09-22 Haozhi Wang , Qing Wang , Yunfeng Shao , Dong Li , Jianye Hao , Yinchuan Li

Multimodal large language models (MLLMs) have demonstrated impressive reasoning and instruction-following capabilities, yet their expanded modality space introduces new compositional safety risks that emerge from complex text-image…

Cryptography and Security · Computer Science 2025-11-18 Xuankun Rong , Wenke Huang , Tingfeng Wang , Daiguo Zhou , Bo Du , Mang Ye

Recent advancements in Large Reasoning Models (LRMs), exemplified by DeepSeek-R1, have underscored the potential of scaling inference-time compute through Group Relative Policy Optimization (GRPO). However, GRPO frequently suffers from…

Artificial Intelligence · Computer Science 2026-02-09 Yu Zhao , Fan Jiang , Tianle Liu , Bo Zeng , Yu Liu , Longyue Wang , Weihua Luo

Prompt engineering, as an efficient and effective way to leverage Large Language Models (LLM), has drawn a lot of attention from the research community. The existing research primarily emphasizes the importance of adapting prompts to…

Computation and Language · Computer Science 2024-07-08 Yuyan Chen , Zhihao Wen , Ge Fan , Zhengyu Chen , Wei Wu , Dayiheng Liu , Zhixu Li , Bang Liu , Yanghua Xiao

Recent advances in large language models (LLMs) have shown strong reasoning capabilities through large-scale pretraining and post-training reinforcement learning, demonstrated by DeepSeek-R1. However, current post-training methods, such as…

Artificial Intelligence · Computer Science 2025-12-04 Boyang Gu , Hongjian Zhou , Bradley Max Segal , Jinge Wu , Zeyu Cao , Hantao Zhong , Lei Clifton , Fenglin Liu , David A. Clifton

Reinforcement learning (RL) has proven remarkably effective at improving the accuracy of language models in verifiable and deterministic domains like mathematics. Here, we examine if current RL methods are also effective at optimizing…

Machine Learning · Computer Science 2025-08-19 Michael Bereket , Jure Leskovec

Large language models (LLMs) trained via pretraining and supervised fine-tuning (SFT) can still produce harmful and misaligned outputs, or struggle in domains like math and coding. Reinforcement learning (RL)-based post-training methods,…

Computation and Language · Computer Science 2026-05-19 Zhichao Wang , Kiran Ramnath , Bin Bi , Shiva Kumar Pentyala , Sougata Chaudhuri , Shubham Mehrotra , Zixu , Zhu , Xiang-Bo Mao , Sitaram Asur , Na , Cheng

Recent advances in constrained reinforcement learning (RL) have endowed reinforcement learning with certain safety guarantees. However, deploying existing constrained RL algorithms in continuous control tasks with general hard constraints…

Machine Learning · Computer Science 2023-12-22 Shutong Ding , Jingya Wang , Yali Du , Ye Shi

Recent advances in Multimodal Large Language Models (MLLMs) have spurred significant progress in Chain-of-Thought (CoT) reasoning. Building on the success of Deepseek-R1, researchers extended multimodal reasoning to post-training paradigms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Jianyu Qi , Ding Zou , Wenrui Yan , Rui Ma , Jiaxu Li , Zhijie Zheng , Zhiguo Yang , Rongchang Zhao
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