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Deep learning models often achieve expert-level accuracy in medical image classification but suffer from a critical flaw: semantic incoherence. These high-confidence mistakes that are semantically incoherent (e.g., classifying a malignant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Abolfazl Mohammadi-Seif , Ricardo Baeza-Yates

Recent vision language models (VLMs) have made remarkable strides in generative modeling with multimodal inputs, particularly text and images. However, their susceptibility to generating harmful content when exposed to unsafe queries raises…

Artificial Intelligence · Computer Science 2026-03-06 Yiwei Chen , Yuguang Yao , Yihua Zhang , Bingquan Shen , Gaowen Liu , Sijia Liu

Fine-tuning on task-specific data to boost downstream performance is a crucial step for leveraging Large Language Models (LLMs). However, previous studies have demonstrated that fine-tuning the models on several adversarial samples or even…

Machine Learning · Computer Science 2024-10-14 Han Shen , Pin-Yu Chen , Payel Das , Tianyi Chen

Backdoor attacks are a significant threat to the performance and integrity of pre-trained language models. Although such models are routinely fine-tuned for downstream NLP tasks, recent work shows they remain vulnerable to backdoor attacks…

Machine Learning · Computer Science 2025-08-28 Santosh Chapagain , Shah Muhammad Hamdi , Soukaina Filali Boubrahimi

Fine-tuning is an essential and pervasive functionality for applying large language models (LLMs) to downstream tasks. However, it has the potential to substantially degrade safety alignment, e.g., by greatly increasing susceptibility to…

Machine Learning · Computer Science 2026-01-16 Jiawen Zhang , Yangfan Hu , Kejia Chen , Lipeng He , Jiachen Ma , Jian Lou , Dan Li , Jian Liu , Xiaohu Yang , Ruoxi Jia

Recent AI agents, such as ChatGPT and LLaMA, primarily rely on instruction tuning and reinforcement learning to calibrate the output of large language models (LLMs) with human intentions, ensuring the outputs are harmless and helpful.…

Computation and Language · Computer Science 2025-02-14 Jingxin Xu , Guoshun Nan , Sheng Guan , Sicong Leng , Yilian Liu , Zixiao Wang , Yuyang Ma , Zhili Zhou , Yanzhao Hou , Xiaofeng Tao

Fine-tuning Large Language Models (LLMs) on specific datasets is a common practice to improve performance on target tasks. However, this performance gain often leads to overfitting, where the model becomes too specialized in either the task…

Computation and Language · Computer Science 2024-09-10 Sonam Gupta , Yatin Nandwani , Asaf Yehudai , Mayank Mishra , Gaurav Pandey , Dinesh Raghu , Sachindra Joshi

In recent years there has been enormous interest in vision-language models trained using self-supervised objectives. However, the use of large-scale datasets scraped from the web for training also makes these models vulnerable to potential…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Alvi Md Ishmam , Christopher Thomas

As large language models (LLMs) become ubiquitous, parameter-efficient fine-tuning methods and safety-first defenses have proliferated rapidly. However, the number of approaches and their recent increase have resulted in diverse…

Machine Learning · Computer Science 2025-06-03 Saad Hossain , Samanvay Vajpayee , Sirisha Rambhatla

Large language models (LLMs) are frequently fine-tuned or unlearned to adapt to new tasks or eliminate undesirable behaviors. While existing evaluation methods assess performance after such interventions, there remains no general approach…

Computation and Language · Computer Science 2025-07-30 Aly M. Kassem , Zhuan Shi , Negar Rostamzadeh , Golnoosh Farnadi

Backdoor attacks represent one of the major threats to machine learning models. Various efforts have been made to mitigate backdoors. However, existing defenses have become increasingly complex and often require high computational resources…

Cryptography and Security · Computer Science 2022-12-20 Zeyang Sha , Xinlei He , Pascal Berrang , Mathias Humbert , Yang Zhang

Recent work has shown that fine-tuning large language models (LLMs) on code with security vulnerabilities can result in misaligned and unsafe behaviors across broad domains. These results prompted concerns about the emergence of harmful…

Machine Learning · Computer Science 2025-07-08 Jeremiah Giordani

Large language models (LLMs) are increasingly deployed in security-sensitive applications, where they must follow system- or developer-specified instructions that define the intended task behavior, while completing benign user requests.…

Cryptography and Security · Computer Science 2026-01-13 Shawn Li , Chenxiao Yu , Zhiyu Ni , Hao Li , Charith Peris , Chaowei Xiao , Yue Zhao

Language models often exhibit undesirable behavior, e.g., generating toxic or gender-biased text. In the case of neural language models, an encoding of the undesirable behavior is often present in the model's representations. Thus, one…

Machine Learning · Computer Science 2025-06-05 Shashwat Singh , Shauli Ravfogel , Jonathan Herzig , Roee Aharoni , Ryan Cotterell , Ponnurangam Kumaraguru

Large Language Models (LLMs) are often trained with safety guards intended to prevent harmful text generation. However, such safety training can be removed by fine-tuning the LLM on harmful datasets. While this emerging threat (harmful…

Computation and Language · Computer Science 2024-10-04 Domenic Rosati , Jan Wehner , Kai Williams , Łukasz Bartoszcze , Jan Batzner , Hassan Sajjad , Frank Rudzicz

Large language models (LLMs) have shown great potential as general-purpose AI assistants in various domains. To meet the requirements of different applications, LLMs are often customized by further fine-tuning. However, the powerful…

Machine Learning · Computer Science 2023-11-07 Xin Zhou , Yi Lu , Ruotian Ma , Tao Gui , Qi Zhang , Xuanjing Huang

Black-box finetuning is an emerging interface for adapting state-of-the-art language models to user needs. However, such access may also let malicious actors undermine model safety. To demonstrate the challenge of defending finetuning…

Cryptography and Security · Computer Science 2024-07-01 Danny Halawi , Alexander Wei , Eric Wallace , Tony T. Wang , Nika Haghtalab , Jacob Steinhardt

As large language models (LLMs) gain popularity, their vulnerability to adversarial attacks emerges as a primary concern. While fine-tuning models on domain-specific datasets is often employed to improve model performance, it can…

Computation and Language · Computer Science 2026-02-24 Punya Syon Pandey , Samuel Simko , Kellin Pelrine , Zhijing Jin

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

Multi-modal large language models (MLLMs) have made significant progress, yet their safety alignment remains limited. Typically, current open-source MLLMs rely on the alignment inherited from their language module to avoid harmful…

Cryptography and Security · Computer Science 2025-04-15 Yanbo Wang , Jiyang Guan , Jian Liang , Ran He