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There is an urgent need for a paradigm shift from group-wise comparisons to individual diagnosis in diffusion MRI (dMRI) to enable the analysis of rare cases and clinically-heterogeneous groups. Deep autoencoders have shown great potential…

Accurate segmentation of punctate white matter lesions (PWMLs) are fundamental for the timely diagnosis and treatment of related developmental disorders. Automated PWMLs segmentation from infant brain MR images is challenging, considering…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Zehua Ren , Yongheng Sun , Miaomiao Wang , Yuying Feng , Xianjun Li , Chao Jin , Jian Yang , Chunfeng Lian , Fan Wang

AI-assisted surgeries have drawn the attention of the medical image research community due to their real-world impact on improving surgery success rates. For image-guided surgeries, such as Cochlear Implants (CIs), accurate object…

Image and Video Processing · Electrical Eng. & Systems 2023-02-17 Yike Zhang , Jack Noble

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

Numerous studies have highlighted that atypical brain development, particularly during infancy and toddlerhood, is linked to an increased likelihood of being diagnosed with a neurodevelopmental condition, such as autism. Accurate brain…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Yilan Dong , Vanessa Kyriakopoulou , Irina Grigorescu , Grainne McAlonan , Dafnis Batalle , Maria Deprez

Purpose: Segmentation of the breast region in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for the automatic measurement of breast density and the quantitative analysis of imaging findings. This study aims to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Sam Narimani , Solveig Roth Hoff , Kathinka Dæhli Kurz , Kjell-Inge Gjesdal , Jurgen Geisler , Endre Grovik

Accurate classification of second-trimester fetal ultrasound images remains challenging due to low image quality, high intra-class variability, and significant class imbalance. In this work, we introduce a simple yet powerful, biologically…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Rinat Prochii , Elizaveta Dakhova , Pavel Birulin , Maxim Sharaev

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

Manual segmentation of medical images is labor intensive and especially challenging for images with poor contrast or resolution. The presence of disease exacerbates this further, increasing the need for an automated solution. To this…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Selena Huisman , Matteo Maspero , Marielle Philippens , Joost Verhoeff , Szabolcs David

Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that…

Methodology · Statistics 2015-06-18 Brian P. Kent , Alessandro Rinaldo , Fang-Cheng Yeh , Timothy Verstynen

Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

Image segmentation is pivotal in medical image analysis, facilitating clinical diagnosis, treatment planning, and disease evaluation. Deep learning has significantly advanced automatic segmentation methodologies by providing superior…

Image and Video Processing · Electrical Eng. & Systems 2026-01-22 Zhengyong Huang , Ning Jiang , Xingwen Sun , Lihua Zhang , Peng Chen , Jens Domke , Yao Sui

White matter tract segmentation is crucial for studying brain structural connectivity and neurosurgical planning. However, segmentation remains challenging due to issues like class imbalance between major and minor tracts, structural…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Anoushkrit Goel , Bipanjit Singh , Ankita Joshi , Ranjeet Ranjan Jha , Chirag Ahuja , Aditya Nigam , Arnav Bhavsar

We propose a geometric deep-learning-based framework, TractGeoNet, for performing regression using diffusion magnetic resonance imaging (dMRI) tractography and associated pointwise tissue microstructure measurements. By employing a point…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yuqian Chen , Leo R. Zekelman , Chaoyi Zhang , Tengfei Xue , Yang Song , Nikos Makris , Yogesh Rathi , Alexandra J. Golby , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Purpose: To implement a brain segmentation pipeline based on convolutional neural networks, which rapidly segments 3D volumes into 27 anatomical structures. To provide an extensive, comparative study of segmentation performance on various…

Image and Video Processing · Electrical Eng. & Systems 2020-08-12 Jonathan Zopes , Moritz Platscher , Silvio Paganucci , Christian Federau

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Our understanding of organs at risk is progressing to include physical small tissues such as coronary arteries and the radiosensitivities of many small organs and tissues are high. Therefore, the accurate segmentation of small volumes in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Jianxin Zhou , Kadishe Fejza , Massimiliano Salvatori , Daniele Della Latta , Gregory M. Hermann , Angela Di Fulvio

We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method…

Neurons and Cognition · Quantitative Biology 2015-12-24 Demian Wassermann , Makris Nikos , Yogesh Rathi , Shenton Martha , Ron Kikinis , Marek Kubicki , Carl-Fredrik Westin